Treatment of pancreatic cancer cells with dicumarol induces cytotoxicity and oxidative stress

Clinical Cancer Research

Volumn 10, Issue 13, 2004, Pages 4550-4558

  Lewis, Anne ^c   Ough, Matthew ^c   Li, Ling ^a   Hinkhouse, Marilyn M ^d   Ritchie, Justine M ^b   Spitz, Douglas R ^a,b   Cullen, Joseph J ^a,b,c,d  

^a Department of Surgery ^*  (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CYTOCHROME C; DIAMINOBENZIDINE; DICOUMAROL; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROQUINONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (QUINONE); SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER INHIBITION; CATALYSIS; CELL KILLING; CELL VIABILITY; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PANCREAS CANCER; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; DICUMAROL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRONS; ENZYME INHIBITORS; FLOW CYTOMETRY; GLUTATHIONE; HUMANS; HYDROQUINONES; MICE; MICE, NUDE; NAD(P)H DEHYDROGENASE (QUINONE); OXIDATIVE STRESS; OXYGEN; PANCREATIC NEOPLASMS; PHENOTYPE; POLY(ADP-RIBOSE) POLYMERASES; QUINONE REDUCTASES; TIME FACTORS; UNCOUPLING AGENTS; VITAMIN K 3;

EID: 3042856798     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-03-0667     Document Type: Article

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