K-ras gene mutational analysis supports a monoclonal origin of biphasic pleomorphic carcinoma of the lung

Modern Pathology

Volumn 17, Issue 5, 2004, Pages 538-546

  Pelosi, Giuseppe ^a,c   Scarpa, Aldo ^b   Manzotti, Michela ^a   Veronesi, Giulia ^c   Spaggiari, Lorenzo ^c   Fraggetta, Filippo ^d   Nappi, Oscar ^e   Benini, Elvira ^a   Pasini, Felice ^b   Antonello, Davide ^b   Iannucci, Antonio ^f   Maisonneuve, Patrick ^c   Viale, Giuseppe ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^d CANNIZZARO HOSPITAL   (Italy)

^e CARDARELLI HOSPITAL   (Italy)

^f City Hosp   (Italy)

Author keywords

Clonality; Histogenesis; Immunohistochemistry; K ras; Lung; Mutation; Pleomorphic carcinoma

Indexed keywords

ALANINE; CYSTEINE; GLYCINE; K RAS PROTEIN; VALINE;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; DISEASE ASSOCIATION; EXON; FEMALE; GENE MUTATION; GENE SEQUENCE; GIANT CELL; HUMAN; IMMUNOHISTOCHEMISTRY; LARGE CELL CARCINOMA; LUNG CARCINOMA; LUNG PLEOMORPHIC CARCINOMA; MALE; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; SPINDLE CELL; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; CARCINOMA, LARGE CELL; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CLONE CELLS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENES, RAS; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; MUTATION, MISSENSE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SMOKING; SURVIVAL ANALYSIS; VIMENTIN;

EID: 3042845278     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3800058     Document Type: Article

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