Ventricular fibrillation: New insights into mechanisms

Annals of the New York Academy of Sciences

Volumn 1015, Issue , 2004, Pages 122-132

  Weiss, James N ^a   Chen, Peng Sheng ^a   Wu, Tsu Juey ^b   Siegerman, Carin ^a   Garfinkel, Alan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Action potential; Arrhythmias; Restitution; Sudden cardiac death

Indexed keywords

CALCIUM CHANNEL L TYPE;

CELL HETEROGENEITY; CONFERENCE PAPER; DISEASE CLASSIFICATION; HEART CONDUCTION; HEART VENTRICLE FIBRILLATION; HUMAN; MOLECULAR DYNAMICS; NONHUMAN; SUDDEN DEATH;

EID: 3042840735     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1302.010     Document Type: Conference Paper

References (61)

1. MOSS, A.J., W. ZAREBA, W.J. HALL, et al. 2002. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N. Engl. J. Med. 346: 877-883.
2. WEISS, J.N., P.S. CHEN, Z. QU, et al. 2000. Ventricular fibrillation: how do we stop the waves from breaking? Circ. Res. 87: 1103-1107.
3. KARMA, A. 1993. Spiral breakup in model equations of action potential propagation in cardiac tissue. Phys. Rev. Lett. 71: 1103-1106.
4. KOLLER, M.L., M.L. RICCIO & R.F. GILMOUR. 1998. Dynamic restitution of the action potential during electrical alternans and ventricular fibrillation. Am. J. Physiol. 275: H1635-1642.
5. QU, Z., J. KIL, F. XIE, et al. 2000 Scroll wave dynamics in a three-dimensional cardiac tissue model: roles of restitution, thickness, and fiber rotation. Biophys. J. 78: 2761-2775.
6. QU, Z., J.N. WEISS & A. GARFINKEL. 1999. Cardiac electrical restitution properties and stability of reentrant spiral waves: a simulation study. Am. J. Physiol. 45: H69-283.
7. RICCIO, M., M. KOLLER & J. GILMOUR. 1999. Electrical restitution and spatiotemporal organization during ventricular fibrillation. Circ. Res. 84: 955-963.
8. GARFINKEL, A., Y.H. KIM, O. VOROSHILOVSKY, et al. 2000. Preventing ventricular fibrillation by flattening cardiac restitution. Proc. Natl. Acad. Sci. USA 97: 6061-6066.
9. LEE, M.H., S.F. LIN, T. OHARA, et al. 2002. Effects of diacetyl monoxime and cytochalasin D on ventricular fibrillation in swine right ventricles. Am J Physiol. 280: H2689-2696.
10. OMICHI, C., S. ZHOU, M.H. LEE, et al. 2002. Effects of amiodarone on wave front dynamics during ventricular fibrillation in isolated swine right ventricle. Am. J. Physiol. 282: H1063-1070.
11. WU, T.J., S.F. LIN, J.N. WEISS, et al. 2002. Two types of ventricular fibrillation in isolated rabbit hearts: importance of excitability and action potential duration restitution. Circulation 106: 1859-1866.
12. NANASI, P.P., A. VARRO & C. PANKUCSI. 1996. Electrical restitution in ventricular myocardium. Clin. Physiol. 16: 561.
13. KARAGUEUZIAN, H.S., S.S. KHAN, K. HONG, et al. 1993. Action potential alternans and irregular dynamics in quinidine-intoxicated ventricular muscle cells. Implications for ventricular proarrhythmia. Circulation 87: 1661-1672.
14. MORGAN, J.M., D. CUNNINGHAM & E. ROWLAND. 1992. Dispersion of monophasic action potential duration: demonstrable in humans after premature ventricular stimulation but not in the steady-state. J. Am. Coll. Cardiol. 19: 1244-1253.
15. COLATSKY, T.J. & P.M. HOGAN. 1980. Effects of external calcium, calcium channel-blocking agents, and stimulation frequency on cycle length-dependent changes in canine cardiac action potential duration. Circ. Res. 46: 543-552.
16. TAGGART, P., M.I. SUTTON, M.R. BOYETT, et al. 1997. Human ventricular action potential duration during short and long cycles: rapid modulation by ischemia. Circulation 94: 2526-2534.
17. DAVIDENKO, J.M., A.V. PERTSOV, J.R. SALOMONSZ, et al. 1992. Stationary and drifting spiral waves of excitation in isolated cardiac muscle. Nature 355: 349-351.
18. FRANZ, M.R., C.D. SWERDLOW, L.B. LIEM & J. SCHAEFER. 1988 Cycle length dependence of human action potential duration in vivo. J. Clin. Invest. 82: 972-979.
19. ELHARRAR, V. & B. SURAWICZ. 1983 Cycle length effect on restitution of action potential duration in dog cardiac fibers. Am. J. Physiol. 244: H782-792.
20. SAGER, P.T., C. FOLLMER, P. UPPAL, et al. 1994. The effects of beta-adrenergic stimulation on the frequency-dependent electrophysiologic actions of amiodarone and sematilide in humans. Circulation 90: 1811-1819.
21. VARRO, A. & D.A. LATHROP. 1990. Sotalol and mexiletine: combination of rate-dependent electrophysiological effects. J. Cardiovasc. Pharmacol. 16: 557-567.
22. MORGAN, J.M., D. CUNNINGHAM & E. ROWLAND. 1992. Electrical restitution in the endocardium of the intact human right ventricle. Br. Heart J. 67: 42-46.
23. VARRO, A., V. ELHARRAR & B. SURAWICZ. 1985. Effect of antiarrhythmic drugs on the premature action potential duration in canine cardiac Purkinje fibers. J. Pharmacol. Exp. Ther. 233: 304-311.
24. TAGGART, P., P. SUTTON, Z. CHALABI, et al. 2003. Effect of adrenergic stimulation on action potential duration restitution in humans. Circulation 107: 285-289.
25. ROBINSON, R.B., P.A. BOYDEN, B.F. HOFFMAN & K.W. HEWETT. 1987. Electrical restitution process in dispersed canine cardiac Purkinje and ventricular cells. Am. J. Physiol. 253: H1018-1025.
26. KIM, B.S., Y.H. KIM, G.S. HWANG, et al. 2002. Action potential duration restitution kinetics in human atrial fibrillation. J. Am. Coll. Cardiol. 39: 1329-1336.
27. max. Br. J. Pharmacol. 103: 1568-1572.
28. WU, T.J., M. YASHIMA, R. DOSHI, et al. 1999. Relation between cellular repolarization characteristics and critical mass for human ventricular fibrillation. J. Cardiovasc. Electrophysiol. 10: 1077-1086.
29. SAITOH, H., J.C. BAILEY & B. SURAWICZ. 1989. Action potential duration alternans in dog Purkinje and ventricular muscle fibers. Further evidence in support of two different mechanisms. Circulation 80: 1421-1431.
30. FRANZ, M.R., P.L. KARASIK, C. LI, et al. 1997. Electrical remodeling of the human atrium: similar effects in patients with chronic atrial fibrillation and atrial flutter. J. Am. Coll. Cardiol. 30: 1785-1792.
31. WATANABE, M., N.F. OTANI & R.F. GILMOUR. 1995. Biphasic restitution of action potential duration and complex dynamics in ventricular myocardium. Circ. Res. 76: 915-921.
32. SAITOH, H., J.C. BAILEY & B. SURAWICZ. 1988. Alternans of action potential duration after abrupt shortening of cycle length: differences between dog Purkinje and ventricular muscle fibers. Circ. Res. 62: 1027-1040.
33. OMICHI, C., M.H. LEE, T. OHARA, et al. 2000. Comparing cardiac action potentials recorded with metal and glass microelectrodes. Am. J. Physiol. 279: H3113-3117.
34. CHINUSHI, M., D. KOZHEVNIKOV, E.B. CAREF, et al. 2003. Mechanism of discordant T wave alternans in the in vivo heart. J. Cardiovasc. Electrophysiol. 14: 632-638.
35. YAMAUCHI, S., M. YAMAKI, T. WATANABE, et al. 2002. Restitution properties and occurrence of ventricular arrhythmia in LQT2 type of long QT syndrome. J. Cardiovasc. Electrophysiol. 13: 910-914.
36. KIM, Y.H., F. XIE, M. YASHIMA, et al. 1999. Role of papillary muscle in the generation and maintenance of reentry during ventricular tachycardia and fibrillation in isolated swine right ventricle. Circulation 100: 1450-1459.
37. WATANABE, T., M. YAMAKI, S. YAMAUCHI, et al. 2002. Regional prolongation of ARI and altered restitution properties cause ventricular arrhythmia in heart failure. Am. J. Physiol. 282: H212-218.
38. SWISSA, M., Z. QU, T. OHARA, et al. 2002. Action potential duration restitution and ventricular fibrillation due to rapid focal excitation. Am. J. Physiol. 282: H1915-1923.
39. SIMURDA, J., M. SIMURDOVA, M. PASEK & P. BRAVENY. 2001. Quantitative analysis of cardiac electrical restitution. Eur. Biophys. J. 30: 500-514.
40. BJORNSTAD, H., P.M. TANDE, D.A. LATHROP & H. REFSUM. 1993. Effects of temperature on cycle length dependent changes and restitution of action potential duration in guinea pig ventricular muscle. Cardiovasc. Res. 27: 946-950.
41. YASHIMA, M., T. OHARA, J.M. CAO, et al. 2000. Nicotine increases ventricular vulnerability to fibrillation in hearts with healed myocardial infarction. Am. J. Physiol. 278: H2124-2133.
42. LAURITA, K.R., S.D. GIROUARD & D.S. ROSENBAUM. 1994. Arrhythmogenic preconditioning by single premature stimuli. PACE 17: 762.
43. CAO, J.M., Z. QU, Y.H. KIM, et al. 1999. Spatiotemporal heterogeneity in the induction of ventricular fibrillation by rapid pacing: importance of cardiac restitution properties. Circ. Res. 84: 1318-1331.
44. ZENG, J., K.R. LAURITA, D.S. ROSENBAUM & Y. RUDY. 1995. Two components of the delayed rectifier K current in ventricular myoytes of the guinea pig type - theoretical formulation and their role in repolarization. Circ. Res. 77: 140-152.
45. LAURITA, K.R., S.D. GIROUARD & D.S. ROSENBAUM. 1996. Modulation of ventricular repolarization by a premature stimulus: role of epicardial dispersion of dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea pig heart. Circ. Res. 79: 493-503.
46. LAURITA, K.R., S.D. GIROUARD, Y. RUDY & D.S. ROSENBAUM. 1997. Role of passive electrical properties during action potential restitution in intact heart. Am. J. Physiol. 273: H1205-1214.
47. LITOVSKY, S.H. & C. ANTZELEVITCH. 1989. Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: role of the transient outward current. J. Am. Coll. Cardiol. 14: 1053-1066.
48. KURZ, R. W., X.L. REN & M.R. FRANZ. 1994. Dispersion and delay of electrical restitution in the globally ischaemic heart. Eur. Heart J. 15: 547-554.
49. BOYETT, M.R. & B.R. JEWELL. 1978. A study of the factors responsible for rate-dependent shortening of the action potential in mammalian ventricular muscle. J. Physiol. 285: 359-380.
50. NOLASCO, J.B. & R.W. DAHLEN. 1968. A graphic method for the study of alternation in cardiac action potentials. J. Appl. Physiol. 25: 191-196.
51. YEHIA, A.R., D. JEANDUPEUX, F. ALONSO & M.R. GUEVARA. 1999. Hysteresis and bistability in the direct transition from 1:1 to 2:1 rhythm in periodically driven single ventricular cells. Chaos 9: 916-931.
52. MOE, G.K., W.C. RHEINBOLDT & J.A. ABILDSKOV. 1964. A computer model of atrial fibrillation. Am. Heart J. 67: 200-220.
53. SAMIE, F.H., R. MANDAPATI, R.A. GRAY, et al. 2000. A mechanism of transition from ventricular fibrillation to tachycardia: effect of calcium channel blockade on the dynamics of rotating waves. Circ. Res. 86: 684-691.
54. WEISFELDT, M.L. & L.B. BECKER. 2002. Resuscitation after cardiac arrest: a 3-phase time-sensitive model. J. Am. Med. Assoc. 288: 3035-3038.
55. ALSEIKHAN, B.A., C.D. DEMARIA, H.M. COLECRAFT & D.T. YUE. 2002. Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation. Proc. Natl. Acad. Sci. USA 99: 17185-17190.
56. GOLDHABER, J.I., C. MOTTER, T.K. DUOUNG & J.N. WEISS. 2002. Cellular basis of action potential duration alternans: role of the L-type Ca current and intracellular Ca cycling. Circulation 106: 11-228.
57. CHUDIN, E., J. GOLDHABER, A. GARFINKEL, et al. 1999. Intracellular Ca dynamics and the stability of ventricular tachycardia. Biophys. J. 77: 2930-2941.
58. XIE, F., J. YANG, Z. QU, et al. 2004. Scroll wave dynamics in anatomically realistic simulated canine ventricles. J. Clin. Invest. In press.
59. VISWANATHAN, P.C., R.M. SHAW & Y. RUDY. 1999. Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation 99: 2466-2474.
60. FOX, J.J., J.L. MCHARG & R.F. GILMOUR, JR. 2002. Ionic mechanism of electrical alternans. Am. J. Physiol. 282: H516-530.
61. FOX J.J., E. BODENSCHATZ & R.F. GILMOUR, JR. 2002. Period-doubling instability and memory in cardiac tissue. Phys. Rev. Lett. 89: 138101.