Key residues contributing to dominant conformational autoantigenic epitopes on thyroid peroxidase identified by mutagenesis

Biochemical and Biophysical Research Communications

Volumn 320, Issue 3, 2004, Pages 795-801

  Gora, Monika ^a   Gardas, Andrzej ^a   Watson, Philip F ^c   Hobby, Paul ^b   Weetman, Anthony P ^c   Sutton, Brian J ^b   Banga, J Paul ^b  

^a MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Autoimmune disease; Immunodominant conformational epitopes; Thyroid peroxidase

Indexed keywords

AMINO ACID; AUTOANTIBODY; AUTOANTIGEN; EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; THYROID PEROXIDASE;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CHO CELL; EUKARYOTE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN LOCALIZATION;

AMINO ACIDS; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; IMMUNODOMINANT EPITOPES; IODIDE PEROXIDASE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EUKARYOTA; MURINAE;

EID: 3042763968     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.06.028     Document Type: Article

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