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Volumn 1024, Issue , 2004, Pages 147-152

L-Carnitine is a modulator of the glucocorticoid receptor alpha

Author keywords

Cytokines; Glucocorticoid receptor alpha; Immunity

Indexed keywords

BETAMETHASONE; CARNITINE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ALPHA; INTERLEUKIN 12; RECEPTOR SUBTYPE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 3042759103     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1321.012     Document Type: Conference Paper
Times cited : (20)

References (35)
  • 1
    • 0031816464 scopus 로고    scopus 로고
    • Carnitine metabolism and its regulation in microorganisms and mammals
    • REBOUCHE, C.J. & H. SEIM. 1998. Carnitine metabolism and its regulation in microorganisms and mammals. Annu. Rev. Nutr. 18: 39-61.
    • (1998) Annu. Rev. Nutr. , vol.18 , pp. 39-61
    • Rebouche, C.J.1    Seim, H.2
  • 2
    • 0002632388 scopus 로고    scopus 로고
    • The role of carnitine in cell metabolism
    • C. De Simone & G. Famularo, Eds.: R.G. Landes Company. Austin, TX
    • BREMER, J. 1997. The role of carnitine in cell metabolism. In Carnitine Today. C. De Simone & G. Famularo, Eds.: 1-37. R.G. Landes Company. Austin, TX.
    • (1997) Carnitine Today , pp. 1-37
    • Bremer, J.1
  • 3
    • 0027049235 scopus 로고
    • Carnitine function and requirements during the life cycle
    • REBOUCHE, C.J. 1992. Carnitine function and requirements during the life cycle. FASEB J. 6: 3379-3386.
    • (1992) FASEB J. , vol.6 , pp. 3379-3386
    • Rebouche, C.J.1
  • 4
    • 0002188416 scopus 로고    scopus 로고
    • Acetyl-L-carnitine: Metabolism and applications in clinical practice
    • FURLONG, J.H. 1996. Acetyl-L-carnitine: metabolism and applications in clinical practice. Altern. Med. Rev. 1.
    • (1996) Altern. Med. Rev. , vol.1
    • Furlong, J.H.1
  • 5
    • 0026622948 scopus 로고
    • Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes
    • ARDUINI, A. et al. 1992. Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes. J. Biol. Chem. 267: 12673-12681.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12673-12681
    • Arduini, A.1
  • 6
    • 0013803903 scopus 로고
    • The role of acylcarnitine esters and carnitine palmityltransferase in the transport of fatty acyl groups across mitochondrial membranes
    • FRITZ, I.B. & N.R. MARQUIS. 1965. The role of acylcarnitine esters and carnitine palmityltransferase in the transport of fatty acyl groups across mitochondrial membranes. Proc. Natl. Acad. Sci. USA 54: 1226-1233.
    • (1965) Proc. Natl. Acad. Sci. USA , vol.54 , pp. 1226-1233
    • Fritz, I.B.1    Marquis, N.R.2
  • 7
    • 0017158408 scopus 로고
    • Carnitine deficiency of skeletal muscle: Report of a treated case
    • ANGELINI, C., S. LUCKE & F. CANTARUTTI. 1976. Carnitine deficiency of skeletal muscle: report of a treated case. Neurology 26: 633-637.
    • (1976) Neurology , vol.26 , pp. 633-637
    • Angelini, C.1    Lucke, S.2    Cantarutti, F.3
  • 8
    • 0021159299 scopus 로고
    • The effect of intravenous L-carnitine on propionic acid excretion in acute propionic acidaemia
    • BOHLES, H. & W. LEHNERT. 1984. The effect of intravenous L-carnitine on propionic acid excretion in acute propionic acidaemia. Eur. J. Pediatr. 143: 61-63.
    • (1984) Eur. J. Pediatr. , vol.143 , pp. 61-63
    • Bohles, H.1    Lehnert, W.2
  • 9
    • 0021238320 scopus 로고
    • L-Carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia
    • ROE, C.R. et al. 1984. L-Carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia. J. Clin. Invest. 73: 1785-1788.
    • (1984) J. Clin. Invest. , vol.73 , pp. 1785-1788
    • Roe, C.R.1
  • 10
    • 0742316797 scopus 로고    scopus 로고
    • L-Carnitine, a "vitamin-like substance" for functional food
    • Proceedings of the Symposium on L-Carnitine, April 28-May 1, 2000, Zermatt, Switzerland
    • WALTER, P. & A.O. SCHAFFHAUSER 2000. L-Carnitine, a "vitamin-like substance" for functional food. Proceedings of the Symposium on L-Carnitine, April 28-May 1, 2000, Zermatt, Switzerland. Ann. Nutr. Metab. 44: 75-96.
    • (2000) Ann. Nutr. Metab. , vol.44 , pp. 75-96
    • Walter, P.1    Schaffhauser, A.O.2
  • 11
    • 0033846487 scopus 로고    scopus 로고
    • Supplements: Questions to ask to reduce confusion
    • BORUM, P.R. 2000. Supplements: questions to ask to reduce confusion. Am. J. Clin. Nutr. 72: 538S-40S.
    • (2000) Am. J. Clin. Nutr. , vol.72
    • Borum, P.R.1
  • 12
    • 0027106265 scopus 로고
    • Control of steroid receptor function and cytoplasmic-nuclear transport by heat shock proteins
    • PRATT, W.B. 1992. Control of steroid receptor function and cytoplasmic-nuclear transport by heat shock proteins. Bioessays 14: 841-848.
    • (1992) Bioessays , vol.14 , pp. 841-848
    • Pratt, W.B.1
  • 13
    • 0029681032 scopus 로고    scopus 로고
    • Molecular chaperoning of steroid hormone receptors
    • PRATT, W.B., U. GEHRING & D.O. TOFT. 1996. Molecular chaperoning of steroid hormone receptors. Experientia Suppl. 77: 79-95.
    • (1996) Experientia Suppl. , vol.77 , pp. 79-95
    • Pratt, W.B.1    Gehring, U.2    Toft, D.O.3
  • 14
    • 0030026713 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
    • BAMBERGER, C.M., H.M. SCHULTE & G.P. CHROUSOS. 1996. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr. Rev. 17: 245-261.
    • (1996) Endocr. Rev. , vol.17 , pp. 245-261
    • Bamberger, C.M.1    Schulte, H.M.2    Chrousos, G.P.3
  • 15
    • 0024246492 scopus 로고
    • Association of the glucocorticoid receptor binding subunit with the 90K nonsteroid-binding component is stabilized by both steroidal and non-steroidal antiglucocorticoids in intact cells
    • LEFEBVRE, P. et al. 1988. Association of the glucocorticoid receptor binding subunit with the 90K nonsteroid-binding component is stabilized by both steroidal and non-steroidal antiglucocorticoids in intact cells. Biochemistry 27: 9186-9194.
    • (1988) Biochemistry , vol.27 , pp. 9186-9194
    • Lefebvre, P.1
  • 16
    • 0030987768 scopus 로고    scopus 로고
    • Disruption of the glucocorticoid receptor assembly with heat shock protein 90 by a peptidic antiglucocorticoid
    • DAO-PHAN, H.P., P. FORMSTECHER & P. LEFEBVRE. 1997. Disruption of the glucocorticoid receptor assembly with heat shock protein 90 by a peptidic antiglucocorticoid. Mol. Endocrinol. 11: 962-972.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 962-972
    • Dao-Phan, H.P.1    Formstecher, P.2    Lefebvre, P.3
  • 17
    • 0030930051 scopus 로고    scopus 로고
    • Inhibition of mineralocorticoid and glucocorticoid receptor function by the heat shock protein 90-binding agent geldanamycin
    • BAMBERGER, C.M. et al. 1997. Inhibition of mineralocorticoid and glucocorticoid receptor function by the heat shock protein 90-binding agent geldanamycin. Mol. Cell Endocrinol. 131: 233-240.
    • (1997) Mol. Cell Endocrinol. , vol.131 , pp. 233-240
    • Bamberger, C.M.1
  • 18
    • 0028887004 scopus 로고
    • Effects of L-carnitine on serum triglyceride and cytokine levels in rat models of cachexia and septic shock
    • WINTER, B.K., G. FISKUM & L.L. GALLO. 1995. Effects of L-carnitine on serum triglyceride and cytokine levels in rat models of cachexia and septic shock. Br. J. Cancer 72: 1173-1179.
    • (1995) Br. J. Cancer , vol.72 , pp. 1173-1179
    • Winter, B.K.1    Fiskum, G.2    Gallo, L.L.3
  • 19
    • 0027358577 scopus 로고
    • LPS-induced serum TNF production and lethality in mice: Effect of L-carnitine and some acyl-derivatives
    • RUGGIERO, V. et al. 1993. LPS-induced serum TNF production and lethality in mice: effect of L-carnitine and some acyl-derivatives. Med. Inflamm. 2: S43-S50.
    • (1993) Med. Inflamm. , vol.2
    • Ruggiero, V.1
  • 20
    • 0027367182 scopus 로고
    • Regulation of normal human polymorphonuclear leucocytes by carnitine
    • FATTOROSSI, A. et al. 1993. Regulation of normal human polymorphonuclear leucocytes by carnitine. Med. Inflamm. 2: S37-S41.
    • (1993) Med. Inflamm. , vol.2
    • Fattorossi, A.1
  • 21
    • 0027515067 scopus 로고
    • Anaesthetics modulate tumour necrosis factor alpha: Effects of L-carnitine supplementation in surgical patients. Preliminary results
    • DELOGU, G. et al. 1993. Anaesthetics modulate tumour necrosis factor alpha: effects of L-carnitine supplementation in surgical patients. Preliminary results. Med. Inflamm. 2: S33-S36.
    • (1993) Med. Inflamm. , vol.2
    • Delogu, G.1
  • 22
    • 0027405265 scopus 로고
    • High dose L-carnitine improves immunologic and metabolic parameters in AIDS patients
    • DE SIMONE, C. et al. 1993. High dose L-carnitine improves immunologic and metabolic parameters in AIDS patients. Immunopharmacol. Immunotoxicol. 15: 1-12.
    • (1993) Immunopharmacol. Immunotoxicol. , vol.15 , pp. 1-12
    • De Simone, C.1
  • 23
    • 0030460718 scopus 로고    scopus 로고
    • Prenatal effects of betamethasone-L-carnitine combinations on fetal rat lung
    • LOHNINGER, A. et al. 1996. Prenatal effects of betamethasone-L-carnitine combinations on fetal rat lung. J. Perinat. Med. 24: 591-599.
    • (1996) J. Perinat. Med. , vol.24 , pp. 591-599
    • Lohninger, A.1
  • 24
    • 0021689334 scopus 로고
    • Comparison of the effects of betamethasone and L-carnitine on dipalmitoylphosphatidylcholine content and phosphatidylcholine species composition in fetal rat lungs
    • LOHNINGER, A. et al. 1984. Comparison of the effects of betamethasone and L-carnitine on dipalmitoylphosphatidylcholine content and phosphatidylcholine species composition in fetal rat lungs. Pediatr. Res. 18: 1246-1252.
    • (1984) Pediatr. Res. , vol.18 , pp. 1246-1252
    • Lohninger, A.1
  • 25
    • 84941841269 scopus 로고
    • Studies on the effects of betamethasone, L-carnitine, and betamethasone-L-carnitine combinations on the dipalmitoyl phosphatidylcholine content and phosphatidylcholine species composition in foetal rat lungs
    • LOHNINGER, A. et al. 1986. Studies on the effects of betamethasone, L-carnitine, and betamethasone-L-carnitine combinations on the dipalmitoyl phosphatidylcholine content and phosphatidylcholine species composition in foetal rat lungs. J. Clin. Chem. Clin. Biochem. 24: 361-368.
    • (1986) J. Clin. Chem. Clin. Biochem. , vol.24 , pp. 361-368
    • Lohninger, A.1
  • 26
    • 0020635012 scopus 로고
    • 1st Report: Alternatives to cortisone therapy. 1st Clinical experiences with a carnitine-betamethasone combination for the stimulation of fetal lung maturity
    • SALZER, H. et al. 1983. 1st report: alternatives to cortisone therapy. 1st clinical experiences with a carnitine-betamethasone combination for the stimulation of fetal lung maturity. Wien Klin. Wochenschr. 95: 724-728.
    • (1983) Wien Klin. Wochenschr. , vol.95 , pp. 724-728
    • Salzer, H.1
  • 27
    • 0027448724 scopus 로고
    • L-Carnitine-betamethasone combination therapy versus betamethasone therapy alone in prevention of respiratory distress syndrome
    • KURZ, C. et al. 1993. L-Carnitine-betamethasone combination therapy versus betamethasone therapy alone in prevention of respiratory distress syndrome. Z. Geburtshilfe Perinatol. 197: 215-219.
    • (1993) Z. Geburtshilfe Perinatol. , vol.197 , pp. 215-219
    • Kurz, C.1
  • 28
    • 0041703026 scopus 로고    scopus 로고
    • L-carnitine: A nutritional modulator of glucocorticoid receptor functions
    • ALESCI, S. et al. 2003. L-carnitine: a nutritional modulator of glucocorticoid receptor functions. FASEB J. 17: 1553-1555.
    • (2003) FASEB J. , vol.17 , pp. 1553-1555
    • Alesci, S.1
  • 29
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • FEARON, D.T. & R.M. LOCKSLEY. 1996. The instructive role of innate immunity in the acquired immune response. Science 272: 50-53.
    • (1996) Science , vol.272 , pp. 50-53
    • Fearon, D.T.1    Locksley, R.M.2
  • 30
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • TRINCHIERI, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13: 251-276.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 31
    • 0030227883 scopus 로고    scopus 로고
    • Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: Clinical implications
    • ELENKOV, I.J. et al. 1996. Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc. Assoc. Am. Physicians 108: 374-381.
    • (1996) Proc. Assoc. Am. Physicians , vol.108 , pp. 374-381
    • Elenkov, I.J.1
  • 32
    • 0027417843 scopus 로고
    • Production of TNF alpha by LPS-stimulated murine, rat and human blood and its pharmacological modulation
    • FOSTER, S.J. et al. 1993. Production of TNF alpha by LPS-stimulated murine, rat and human blood and its pharmacological modulation. Agents Actions 38: C77-79.
    • (1993) Agents Actions , vol.38
    • Foster, S.J.1
  • 33
    • 0025995796 scopus 로고
    • Suppressive effect of 1,25(OH)2D3 and glucocorticoids on production of tumor necrosis factor alpha by human peripheral blood adherent cells
    • KATAKAMI, N., Y. NAKAO & T. FUJITA. 1991. Suppressive effect of 1,25(OH)2D3 and glucocorticoids on production of tumor necrosis factor alpha by human peripheral blood adherent cells. Kobe J. Med. Sci. 37: 179-188.
    • (1991) Kobe J. Med. Sci. , vol.37 , pp. 179-188
    • Katakami, N.1    Nakao, Y.2    Fujita, T.3
  • 34
    • 0032984367 scopus 로고    scopus 로고
    • Carnitine and dehydroepiandrosterone sulfate induce protein synthesis in porcine primary osteoblast-like cells
    • CHIU, K.M. et al. 1999. Carnitine and dehydroepiandrosterone sulfate induce protein synthesis in porcine primary osteoblast-like cells. Calcif. Tissue Int. 64: 527-533.
    • (1999) Calcif. Tissue Int. , vol.64 , pp. 527-533
    • Chiu, K.M.1
  • 35
    • 0034880632 scopus 로고    scopus 로고
    • Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: A randomized, double-blind, placebo-controlled clinical trial
    • BENVENGA, S. et al. 2001. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J. Clin. Endocrinol. Metab. 86: 3579-3594.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 3579-3594
    • Benvenga, S.1


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