Phosphorylation of ERK and CREB in cultured hippocampal neurons after haloperidol and risperidone administration

Psychiatry and Clinical Neurosciences

Volumn 58, Issue 3, 2004, Pages 262-267

  Yang, Byung Hwan ^a   Son, Hyeon ^a   Hyeon Kim, Seok ^a   Nam, Jung Hyun ^a   Choi, Joon Ho ^a   Lee, Jun Seok ^b  

^a Hanyang University   (South Korea)

^b Catholic Kwandong University   (South Korea)

Author keywords

CREB; ERK; Haloperidol; Hippocampal neuron; Risperidone

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; FORSKOLIN; HALOPERIDOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; NEUROLEPTIC AGENT; RISPERIDONE; SERINE; THREONINE;

ANTIBODY SPECIFICITY; ANTIGEN RECOGNITION; ARTICLE; CELL MATURATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PSYCHOSIS; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTIPSYCHOTIC AGENTS; BLOTTING, WESTERN; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FORSKOLIN; HALOPERIDOL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHORYLATION; RATS; RISPERIDONE;

EID: 3042743789     PISSN: 13231316     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1819.2004.01229.x     Document Type: Article

References (28)

1. Joyce JN, Goldsmith SG, Gurevich EV. Limbic circuits and monoamine receptors: dissecting the effects of antipsychotics from disease processes. J. Psychiatr. Res. 1997; 31: 197-217.
2. Creese I, Burt DR, Snyder SH. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 1976; 192: 481-483.
3. Konradi C, Hecker S. Antipsychotic drugs and neuroplasticity: insights into the treatment and neurobiology of schizophrenia. Biol. Psychiatry 2001; 50: 729-742.
4. Impey S, Obrietan K, Wong ST et al. Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron 1998; 21: 869-883.
5. Kyosseva SV, Elbein AD, Griffin WS, Mrak RE, Lyon M, Karson CN. Mitogen-activated protein kinases in schizophrenia. Biol. Psychiatry 1999; 46: 689-696.
6. Meyer TE, Habener JF. Cyclic adenosine 3′,5′-monophosphate response element binding protein (CREB) and related transcription-activating deoxyribonueleic acid-binding proteins. Endocr. Rev. 1993; 14: 269-290.
7. Montminy MR, Gonzalez GA, Yamamoto KK. Regulation of cAMP-inducible genes by CREB. Trends Neurosci. 1990; 13: 184-188.
8. Imaki J, Yoshida K, Yamashita K. A developmental study of cyclic AMP-response element binding protein (CREB) by in situ hybridization histochemistry and immunocytochemistry in the rat neocortex. Brain Res. 1994; 651: 269-274.
9. Ginty DD, Kornhauser JM, Thompson MA et al. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and circadian clock. Science 1993; 260: 238-241.
10. Miyasaka T, Chao MV, Sherline P, Saltiel AR. Nerve growth factor stimulates a protein kinase in PC-12 cells that phosphorylate microtubule-associated protein-2. J. Biol. Chem. 1990; 265: 4730-4735.
11. Boulton TG, Nye SH, Robbins DJ et al. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in responses to insulin and NGF. Cell 1991; 65: 663-675.
12. Bading H, Greenberg ME. Stimulation of protein tyrosine phosphorylation by NMDA receptor activation. Science 1991; 253: 912-914.
13. Fiore RS, Murphy TH, Sanghera JS, Pelech SL, Baraban JM. Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures. J. Neurochem. 1993; 61: 1626-1633.
14. Rosenblum K, Futter M, Jones M, Hulme EC, Bliss TV. ERKI/II regulation by the muscarinic acetylcholine receptors in neurons. J. Neurosci. 2000; 20: 977-985.
15. Kanterewicz BI, Knapp LT, Klann E. Stimulation of p42 and p44 mitogen-activated protein kinases by reactive oxygen species and nitric oxide in hippocampus. J. Neurochem. 1998; 70: 1009-1016.
16. Lewis TS, Shapiro PS, Ahn NG. Signal transduction through MAP kinase cascades. Adv. Cancer Res. 1998; 74: 49-139.
17. Berman DE, Hazvi S, Rosenblum K, Seger R, Dudai Y. Specific and differential activation of mitogen-activated protein cascades by unfamiliar taste in insular cortex of the behaving rat. J. Neurosci. 1998; 18: 10 037-10 044.
18. Blum S, Moore AN, Adams F, Dash PK. A mitogen-activated protein cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory. J. Neurosci. 1999; 19: 3535-3544.
19. Sgambato V, Pages C, Rogard M, Besson MJ, Caboche J. Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation. J. Neurosci. 1998; 18: 8814-8825.
20. Bartlett WP, Banker GA. An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts. J. Neurosci. 1984; 4: 1944-1953.
21. Sheng M, Thompson MA, Greenberg ME. CREB: a Ca (2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 1991; 252: 1427-1430.
22. Seeman P, Lee T. Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 1975; 188: 1217-1219.
23. Albert PR, Neve KA, Bunzow JR, Civelli O. Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion. J. Biol. Chem. 1990; 265: 2098-2104.
24. Gonzalez GA, Montminy MR. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 1989; 59: 675-680.
25. Adams MR, Brandon EP, Chartoff EH, Idzerda RL, Dorsa DM, McKnight GS. Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice. Proc. Natl Acad. Sci. USA 1997; 94: 12 157-12 161.
26. Troadec JD, Marien M, Mourlevat S et al. Activation of the mitogen-activated protein kinase (ERK1/2) signaling pathway by cyclic AMP potentiates the neuroprotective effect of the neurotransmitter noradrenaline on dopaminergic neurons. Mol. Pharmacol. 2002; 62: 1043-1052.
27. Lidow MS, Goldman-Rakic PS. Differential regulation of D2 and D4 dopamine receptor mRNAs in the primate cerebral cortex vs. neostriatum: effects of chronic treatment with typical and atypical antipsychotic drugs. J. Pharmacol. Exp. Ther. 1997; 283: 939-946.
28. Hsieh HC, Li HY, Lin MY et al. Spatial and temporal profile of haloperidol-induced immediate-early gene expression and phosphoCREB binding in the dorsal and ventral striatum of amphetamine-sensitized rats. Synapse 2002; 45: 230-244.