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Volumn 21, Issue 6, 2004, Pages 460-470

The systemic absorption and disposition of levobupivacaine 0.5% after epidural administration in surgical patients: A stable-isotope study

Author keywords

Anaesthetic techniques, epidural; Anaesthetics, local, levobupivacaine; Human experimentation; Pharmacokinetics, levobupivacaine

Indexed keywords

DEUTERIUM; ISOTOPE; LEVOBUPIVACAINE;

EID: 3042742657     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0265021504006088     Document Type: Article
Times cited : (21)

References (31)
  • 1
    • 0025768176 scopus 로고
    • Disposition of mepivacaine and bupivacaine enantiomers in sheep
    • Mather LE. Disposition of mepivacaine and bupivacaine enantiomers in sheep. Br J Anaesth 1991; 67: 239-246.
    • (1991) Br J Anaesth , vol.67 , pp. 239-246
    • Mather, L.E.1
  • 2
    • 0028674588 scopus 로고
    • Pharmacokinetics of bupivacaine enantiomers in sheep: Influence of dosage regimen and study design
    • Mather LE, Rutten AJ, Plummer JL. Pharmacokinetics of bupivacaine enantiomers in sheep: influence of dosage regimen and study design. J Pharmacokinet Biopharm 1994; 22: 481-498.
    • (1994) J Pharmacokinet Biopharm , vol.22 , pp. 481-498
    • Mather, L.E.1    Rutten, A.J.2    Plummer, J.L.3
  • 4
    • 0031937088 scopus 로고    scopus 로고
    • Pharmacokinetics of the enantiomers of bupivacaine and mepivacaine after epidural administration of the racemates
    • Groen K, Mantel M, Zeijlmans PWM, et al. Pharmacokinetics of the enantiomers of bupivacaine and mepivacaine after epidural administration of the racemates. Anesth Analg 1998; 86: 361-366.
    • (1998) Anesth Analg , vol.86 , pp. 361-366
    • Groen, K.1    Mantel, M.2    Zeijlmans, P.W.M.3
  • 5
    • 0026751014 scopus 로고
    • Stereoselective inhibition of neuronal sodium channels by local anesthetics
    • Lee-Son S, Wang GK, Concus A, Crill E, Strichartz G. Stereoselective inhibition of neuronal sodium channels by local anesthetics. Anesthesiology 1992; 77: 324-335.
    • (1992) Anesthesiology , vol.77 , pp. 324-335
    • Lee-Son, S.1    Wang, G.K.2    Concus, A.3    Crill, E.4    Strichartz, G.5
  • 6
    • 0033951932 scopus 로고    scopus 로고
    • Comparisons of the anesthetic potency and intracellular concentrations of S(-) and R(+) bupivacaine and ropivacaine in crayfish giant axon in vitro
    • Kanai Y, Katsuki H, Takasaki M. Comparisons of the anesthetic potency and intracellular concentrations of S(-) and R(+) bupivacaine and ropivacaine in crayfish giant axon in vitro. Anesth Analg 2000; 90: 415-420.
    • (2000) Anesth Analg , vol.90 , pp. 415-420
    • Kanai, Y.1    Katsuki, H.2    Takasaki, M.3
  • 7
    • 0025860073 scopus 로고
    • Stereoselective effects of the enantiomers of bupivacaine on the electrophysiological properties of the guinea-pig papillary muscle
    • Vanhoutte F, Vereecke J, Verbeke N, Carmeliet E. Stereoselective effects of the enantiomers of bupivacaine on the electrophysiological properties of the guinea-pig papillary muscle. Br J Pharmacol 1991; 103: 1275-1281.
    • (1991) Br J Pharmacol , vol.103 , pp. 1275-1281
    • Vanhoutte, F.1    Vereecke, J.2    Verbeke, N.3    Carmeliet, E.4
  • 8
    • 0027049954 scopus 로고
    • Enantiomer-specific effects of an intravenously administered arrhythmogenic dose of bupivacaine on neurons of the nucleus tractus solitarius and the cardiovascular system in the anesthetized rat
    • Denson DD, Behbehani MM, Gregg RV. Enantiomer-specific effects of an intravenously administered arrhythmogenic dose of bupivacaine on neurons of the nucleus tractus solitarius and the cardiovascular system in the anesthetized rat. Reg Anesth 1992; 17: 311-316.
    • (1992) Reg Anesth , vol.17 , pp. 311-316
    • Denson, D.D.1    Behbehani, M.M.2    Gregg, R.V.3
  • 9
    • 0033812844 scopus 로고    scopus 로고
    • Comparative ventricular electrophysiologic effect of racemic bupivacaine, levobupivacaine, and ropivacaine on the isolated rabbit heart
    • Mazoit JX, Decaux A, Bouaziz H, Edouard A. Comparative ventricular electrophysiologic effect of racemic bupivacaine, levobupivacaine, and ropivacaine on the isolated rabbit heart. Anesthesiology 2000; 93: 784-792.
    • (2000) Anesthesiology , vol.93 , pp. 784-792
    • Mazoit, J.X.1    Decaux, A.2    Bouaziz, H.3    Edouard, A.4
  • 10
    • 0032901485 scopus 로고    scopus 로고
    • Recent advances in the pharmacokinetics of local anaesthetics. Long-acting amide enantiomers and continuous infusions
    • Thomas JM, Schug SA. Recent advances in the pharmacokinetics of local anaesthetics. Long-acting amide enantiomers and continuous infusions. Clin Pharmacokinet 1999; 36: 67-83.
    • (1999) Clin Pharmacokinet , vol.36 , pp. 67-83
    • Thomas, J.M.1    Schug, S.A.2
  • 11
    • 0033936439 scopus 로고    scopus 로고
    • Levobupivacaine: New preclinical and clinical data
    • Gennery B, Mather LE, Strichartz G. Levobupivacaine: new preclinical and clinical data. Semin Anesth 2000; 19: 132-148.
    • (2000) Semin Anesth , vol.19 , pp. 132-148
    • Gennery, B.1    Mather, L.E.2    Strichartz, G.3
  • 12
    • 0023414508 scopus 로고
    • Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration. Simultaneous investigation of absorption and disposition kinetics using stable isotopes
    • Burm AGL, Vermeulen NPE, Van Kleef JW, De Boer AG, Spierdijk J, Breimer DD. Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration. Simultaneous investigation of absorption and disposition kinetics using stable isotopes. Clin Pharmacokinet 1987; 13: 191-203.
    • (1987) Clin Pharmacokinet , vol.13 , pp. 191-203
    • Burm, A.G.L.1    Vermeulen, N.P.E.2    Van Kleef, J.W.3    De Boer, A.G.4    Spierdijk, J.5    Breimer, D.D.6
  • 13
    • 0023833237 scopus 로고
    • Pharmacokinetics of lidocaine and bupivacaine and stable isotope labelled analogues: A study in healthy volunteers
    • Burm AGL, De Boer AG, Van Kleef JW, et al. Pharmacokinetics of lidocaine and bupivacaine and stable isotope labelled analogues: a study in healthy volunteers. Biopharm Drug Dispos 1988; 9: 85-95.
    • (1988) Biopharm Drug Dispos , vol.9 , pp. 85-95
    • Burm, A.G.L.1    De Boer, A.G.2    Van Kleef, J.W.3
  • 14
    • 0032983947 scopus 로고    scopus 로고
    • Clinical effects and maternal and fetal plasma concentrations of 0.5% epidural levobupivacaine versus bupivacaine for cesarean delivery
    • Bader AM, Tsen LC, Camann WR, Nephew E, Datta S. Clinical effects and maternal and fetal plasma concentrations of 0.5% epidural levobupivacaine versus bupivacaine for cesarean delivery. Anesthesiology 1999; 90: 1596-1601.
    • (1999) Anesthesiology , vol.90 , pp. 1596-1601
    • Bader, A.M.1    Tsen, L.C.2    Camann, W.R.3    Nephew, E.4    Datta, S.5
  • 15
    • 0034051447 scopus 로고    scopus 로고
    • A comparison of epidural levobupivacaine 0.75% with racemic bupivacaine for lower abdominal surgery
    • Kopacz DJ, Allen HW, Thompson GE. A comparison of epidural levobupivacaine 0.75% with racemic bupivacaine for lower abdominal surgery. Anesth Analg 2000; 90: 642-648.
    • (2000) Anesth Analg , vol.90 , pp. 642-648
    • Kopacz, D.J.1    Allen, H.W.2    Thompson, G.E.3
  • 16
    • 0019274427 scopus 로고
    • The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time
    • Riegelman S, Collier P. The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time. J Pharmacokinet Biopharm 1980; 8: 509-534.
    • (1980) J Pharmacokinet Biopharm , vol.8 , pp. 509-534
    • Riegelman, S.1    Collier, P.2
  • 17
    • 0018606615 scopus 로고
    • Noncompartmental determination of the steady-state volume of distribution
    • Benet LZ, Galeazzi RL. Noncompartmental determination of the steady-state volume of distribution. J Pharm Sci 1979; 68: 1071-1074.
    • (1979) J Pharm Sci , vol.68 , pp. 1071-1074
    • Benet, L.Z.1    Galeazzi, R.L.2
  • 18
    • 0019974468 scopus 로고
    • Noncompartmental determination of the steady-state volume of distribution for any mode of administration
    • Perrier D, Mayersohn M. Noncompartmental determination of the steady-state volume of distribution for any mode of administration. J Pharm Sci 1982; 71: 372-373.
    • (1982) J Pharm Sci , vol.71 , pp. 372-373
    • Perrier, D.1    Mayersohn, M.2
  • 19
    • 0022541667 scopus 로고
    • Estimation of drug absorption rates using a deconvolution method with nonequal sampling times
    • Iga K, Ogawa Y, Yashiki T, Shimamoto T. Estimation of drug absorption rates using a deconvolution method with nonequal sampling times. J Pharmacokinet Biopharm 1986; 14: 213-225.
    • (1986) J Pharmacokinet Biopharm , vol.14 , pp. 213-225
    • Iga, K.1    Ogawa, Y.2    Yashiki, T.3    Shimamoto, T.4
  • 21
    • 0025137182 scopus 로고
    • Review of methods and criteria for the evaluation of bioequivalence studies
    • Pabst G, Jaeger H. Review of methods and criteria for the evaluation of bioequivalence studies. Eur J Clin Pharmacol 1990; 38: 5-10.
    • (1990) Eur J Clin Pharmacol , vol.38 , pp. 5-10
    • Pabst, G.1    Jaeger, H.2
  • 22
    • 0023615056 scopus 로고
    • A comparison of the two one-sided tests procedure and the power approach for assessing the equivalence of average bioavailability
    • Schuirmann DJ. A comparison of the two one-sided tests procedure and the power approach for assessing the equivalence of average bioavailability. J Pharmacokinet Biopharm 1987; 15: 657-680.
    • (1987) J Pharmacokinet Biopharm , vol.15 , pp. 657-680
    • Schuirmann, D.J.1
  • 24
    • 0033052870 scopus 로고    scopus 로고
    • Levobupivacaine: A new safer long acting local anaesthetic agent
    • Gristwood RW, Greaves JL. Levobupivacaine: a new safer long acting local anaesthetic agent. Expert Opin Invest Drug 1999; 8: 861-876.
    • (1999) Expert Opin Invest Drug , vol.8 , pp. 861-876
    • Gristwood, R.W.1    Greaves, J.L.2
  • 25
    • 0016467703 scopus 로고
    • Pharmacology of local anaesthetic agents. Pharmacokinetics of local anaesthetic agents
    • Tucker GT, Mather LE. Pharmacology of local anaesthetic agents. Pharmacokinetics of local anaesthetic agents. Br J Anaesth 1975; 47: 213-224.
    • (1975) Br J Anaesth , vol.47 , pp. 213-224
    • Tucker, G.T.1    Mather, L.E.2
  • 26
    • 0031439403 scopus 로고    scopus 로고
    • Systemic absorption and block after epidural injection of ropivacaine in healthy volunteers
    • Emanuelsson BM, Persson J, Alm C, Heller A, Gustafsson LL. Systemic absorption and block after epidural injection of ropivacaine in healthy volunteers. Anesthesiology 1997; 87: 1309-1317.
    • (1997) Anesthesiology , vol.87 , pp. 1309-1317
    • Emanuelsson, B.M.1    Persson, J.2    Alm, C.3    Heller, A.4    Gustafsson, L.L.5
  • 27
    • 0017819596 scopus 로고
    • An intradermal study of the local anaesthetic and vascular effects of the isomers of bupivacaine
    • Aps C, Reynolds F. An intradermal study of the local anaesthetic and vascular effects of the isomers of bupivacaine. Br J Clin Pharmacol 1978; 6: 63-68.
    • (1978) Br J Clin Pharmacol , vol.6 , pp. 63-68
    • Aps, C.1    Reynolds, F.2
  • 28
    • 0033856091 scopus 로고    scopus 로고
    • The addition of dilute epinephrine produces equieffectiveness of bupivacaine enantiomers for cutaneous analgesia in the rat
    • Khodorova AB, Strichartz GR. The addition of dilute epinephrine produces equieffectiveness of bupivacaine enantiomers for cutaneous analgesia in the rat. Anesth Analg 2000; 91: 410-416.
    • (2000) Anesth Analg , vol.91 , pp. 410-416
    • Khodorova, A.B.1    Strichartz, G.R.2
  • 29
    • 0033749362 scopus 로고    scopus 로고
    • Skin blood flow changes in response to intradermal injection of bupivacaine and levobupivacaine, assessed by laser Doppler imaging
    • Newton DJ, Burke D, Khan F, et al. Skin blood flow changes in response to intradermal injection of bupivacaine and levobupivacaine, assessed by laser Doppler imaging. Reg Anesth Pain Med 2000; 25: 626-631.
    • (2000) Reg Anesth Pain Med , vol.25 , pp. 626-631
    • Newton, D.J.1    Burke, D.2    Khan, F.3
  • 30
    • 0032983947 scopus 로고    scopus 로고
    • Clinical effects and maternal and fetal plasma concentrations of 0.5% epidural levobupivacaine versus bupivacaine for cesarean delivery
    • Bader AM, Tsen LC, Camann WR, Nephew E, Datta S. Clinical effects and maternal and fetal plasma concentrations of 0.5% epidural levobupivacaine versus bupivacaine for cesarean delivery. Anesthesiology 1999; 90: 1596-1601.
    • (1999) Anesthesiology , vol.90 , pp. 1596-1601
    • Bader, A.M.1    Tsen, L.C.2    Camann, W.R.3    Nephew, E.4    Datta, S.5


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