Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population

Biochemical Journal

Volumn 380, Issue 3, 2004, Pages 897-905

  Wäsle, Barbara ^a   Hays, Lori B ^b   Rhodes, Christopher J ^b   Edwardson, J Michael ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

AtT 20 cells; Corticotropin; Exocytosis; Secretory vesicle; Syncollin

Indexed keywords

CELL MEMBRANES; CELLS; ENZYMES; FLUORESCENCE; HORMONES; MECHANICAL PERMEABILITY; OLIGOMERS;

CORTICOTROPIN; HOMO-OLIGOMERS;

BIOCHEMISTRY;

ADENOVIRUS VECTOR; ALKALINE PHOSPHATASE; CORTICOTROPIN; GREEN FLUORESCENT PROTEIN; OLIGOMER; PROTEIN; SYNCOLLIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PERMEABILIZATION; CELL STRAIN; CONTROLLED STUDY; CORTICOTROPIN RELEASE; ERYTHROCYTE; EXOCYTOSIS; EXPERIMENTAL INFECTION; MOUSE; NEUROSECRETORY CELL; NONHUMAN; PANCREAS; PLASMACYTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SECRETION; RAT; SECRETORY VESICLE;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; CARRIER PROTEINS; CELL LINE; HUMANS; MEMBRANE PROTEINS; MICE; NEURONS; NEUROSECRETORY SYSTEMS; SECRETORY VESICLES;

ADENOVIRIDAE; ANIMALIA; HOMO;

EID: 3042699603     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031726     Document Type: Article

References (29)

1. 2+-sensitive manner. Cell (Cambridge, Mass.) 90, 325-333
2. An, S. J., Hansen, N. J., Hodel, A., Jahn, R. and Edwardson, J. M. (2000) Analysis of the association of syncollin with the membrane of the pancreatic zymogen granule. J. Biol. Chem. 275, 11306-11311
3. Geisse, N. A., Wäsle, B., Saslowsky, D. E., Henderson, R. M. and Edwardson, J. M. (2002) Syncollin homo-oligomers associate with lipid bilayers in the form of doughnut-shaped structures. J. Membr. Biol. 89, 83-92
4. Hodel, A., An, S. J., Hansen, N. J., Lawrence, J., Wäsle, B., Schrader, M. and Edwardson, J. M. (2001) Cholesterol-dependent interaction of syncollin with the membrane of the pancreatic zymogen granule. Biochem. J. 356, 843-850
5. Kalus, I., Hodel, A., Koch, A., Kleene, R., Edwardson, J. M. and Schrader, M. (2002) Interaction of syncollin with GP-2, the major membrane protein of pancreatic zymogen vesicles, and association with lipid microdomains. Biochem. J. 362, 433-442
6. Tan, S. and Hooi, S. C. (2000) Syncollin is differentially expressed in rat proximal small intestine and regulated by feeding behaviour. Am. J. Physiol. 278, G308-G320
7. Antonin, W., Wagner, M., Riedel, D., Brose, N. and Jahn, R. (2002) Loss of the zymogen granule protein syncollin affects pancreatic synthesis and transport but not secretion. Moll. Cell. Biol. 22, 1545-1554
8. He, T. C., Zhou, S., da Costa, L. T., Yu, J., Kinzler, K. W. and Vogelstein, B. (1998) A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. U.S.A. 95, 2509-2514
9. Dickson, L. M., Lingohr, M. K., McCuag, J., Hugl, S. R., Snow, L., Kahn, B. B., Myers, Jr. M. G. and Rhodes, C. J. (2001) Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic β-cells (INS-1). J. Biol. Chem 276, 21110-21120
10. Molinete, M., Lilla, V., Jain, R., Joyce, P. B., Gorr, S. U., Ravazzola, M. and Halban, P. A. (2000) Trafficking of non-regulated secretory proteins in insulin secreting (INS-1) cells. Diabetologia 43, 1157-1164
11. 4 receptors in NG108-15 cells. Eur. J. Pharmacol. 428, 9-18
12. McFerran, B. W. and Guild, S. B. (1994) Effects of protein kinase C activators upon the late stages of the ACTH secretory pathway of AtT-20 cells. Br. J. Pharmacol. 113, 171-178
13. McFerran, B. W. and Guild, S. B. (1995) Effects of mastoparan upon the late stages of the ACTH secretory pathway of AtT-20 cells. Br. J. Pharmacol. 115, 696-702
14. Majó, G., Aguado, F., Blasi, J. and Marsal, J. (1998) Synaptobrevin isoforms in secretory vesicles and synaptic-like micravesicles in anterior pituitary cells. Life Sci. 62, 607-616
15. Hodel, A. and Edwardson, J. M. (2000) Targeting of the zymogen-granule protein syncollin in AR42J and AtT-20 cells. Biochem. J. 350, 637-643
16. Navone, F., Di Gioia, G., Jahn, R., Browning, M., Greengard, P. and De Camilli, P. (1989) Microvesicles of the neurohypophysis are biochemically related to small synaptic vesicles of presynaptic nerve teminals. J. Cell Biol. 109, 3425-3433
17. Reetz, A., Solimena, M., Matteoli, M., Folli, F., Takei, K. and De Camilli, P. (1991) GABA and pancreatic β-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion. EMBO J. 10, 1275-1284
18. Baumert, M., Maycox, P. R., Navone, F., De Camilli, P. and Jahn, R. (1989) Synaptobrevin: an integral membrane protein of 18 000 daltons present in small synaptic vesicles of rat brain. EMBO J. 8, 379-384
19. Castro, M. G., Goya, R. G., Sosa, Y. E., Rowe, J., Larregina, A., Morelli, A. and Lowenstein, P. R. (1997) Expression of transgenes in normal and neoplastic anterior pituitary cells using recombinant adenoviruses: long term expression, cell cycle dependency, and effects on hormone secertion. Endocrinology 138, 2184-2194
20. Hess, O. T., Slater, T. M., Wilson, M. C. and Skene, J. H. (1992) The 25 kDa synaptosomal-associaled protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS. J. Neurosci. 12, 4634-4641
21. Jain, R. K., Joyce, P. B., Molinete, M., Halban, P. A. and Gorr, S. U. (2001) Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells. Biochem. J. 360, 645-649
22. Cabana, C., Magny, P., Nadeau, D., Grondin, G. and Beaudoin, A. (1987) Freeze-fracture study of the zymogen granule membrane of pancreas: two novel types of intramembrane particles. Eur. J. Cell Biol. 45, 246-255
23. Orci, L., Miller, R. G., Montesano, R., Perrelet, A., Amherdt, M. and Vassalli, P. (1980) Opposite polarity of filipin-induced deformations in the membrane of condensing vacuoles and zymogen granules. Science 210, 1019-1021
24. Hertle, R. (2002) Serratia marcescens hemolysin (ShlA) binds artificial membranes and forms pores in a receptor-independent manner. J. Membr. Biol. 189, 1-14
25. Goncz, K. K. and Rothman, S. (1992) Protein flux across the membrane of single secretion granules. Biochim. Biophys. Acta 1109, 7-16
26. Goncz, K. K. and Rothman, S. (1992) A trans-membrane pore can account for protein movement across zymogen granule membranes. Biochim. Biophys. Acta 1238, 91-93
27. Edelmann, L., Hanson, P. I., Chapman, E. R. and Jahn, R. (1995) Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic membrane fusion machine. EMBO J. 14, 224-231
28. Barnstable, C. J., Hofstein, R. and Akagawa, K. (1985) A marker of early amacrine cell development in rat retina. Dev. Brain Res. 20, 286-290
29. Xu, T., Rammner, B., Margittai, M., Artalejo, A. R., Neher, E. and Jahn, R. (1999) Inhibition of SNARE complex assembly differentially affects kinetic components of exocytosis. Cell (Cambridge, Mass.) 99, 713-722