Non-cholinergic excitation in neurons after a chronic glutamate receptor blockade

NeuroReport

Volumn 15, Issue 1, 2004, Pages 113-117

  Belousov, Andrei B ^a   Arumugam, Harsha ^a   Denisova, Janna V ^a  

^a Tulane University   (United States)

Author keywords

Acetylcholine; ATP; Gap junctions; Glutamate; Histamine; Metabotropic glutamate receptors; Nitric oxide; Noradrenaline

Indexed keywords

ADRENERGIC RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; HISTAMINE RECEPTOR; METABOTROPIC RECEPTOR; PURINE P2 RECEPTOR; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT;

ANIMAL TISSUE; ARTICLE; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; EMBRYO; GAP JUNCTION; HYPOTHALAMUS; NERVE CONDUCTION; NEUROIMAGING; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; ACTION POTENTIAL; ANIMAL; CELL CULTURE; DRUG EFFECT; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANIMALS; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUTAMATE;

EID: 3042698848     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200401190-00023     Document Type: Article

References (15)

1. Belousov AB, O'Hara BF and Denisova JV. Acetylcholine becomes the major excitatory neurotransmitter in the hypothalamus in vitro in the absence of glutamate excitation. J Neurosci 21, 2015-2027 (2001).
2. Belousov AB, Hunt ND, Raju RP and Denisova JV. Calcium-dependent regulation of cholinergic cell phenotype in the hypothalamus in vitro. J Neurophysiol 88, 1352-1362 (2002).
3. Belousov AB and van den Pol AN. Local synaptic release of glutamate from neurons in the rat hypothalamic arcuate nucleus. J Physiol (Lond) 499, 747-761 (1997).
4. van den Pol AN, Wuarin JP and Dudek FE. Glutamate, the dominant excitatory transmitter in neuroendocrine regulation. Science 250, 1276-1278 (1990).
5. Jo YH and Role LW. Coordinate release of ATP and GABA at in vitro synapses of lateral hypothalamic neurons. J Neurosci 22, 4794-4804 (2002).
6. Haas H and Panula P. The role of histamine and the tuberomamillary nucleus in the nervous system. Nature Rev Neurosci 4, 121-130 (2003).
7. Ghosh PK, Baskaran N and van den Pol AN. Developmentally regulated gene expression of all eight metabotropic glutamate receptors in hypothalamic suprachiasmatic and arcuate nuclei - a PCR analysis. Brain Res Dev Brain Res 102, 1-12 (1997).
8. Xiang Z, Bo X, Oglesby I, Ford A and Burnstock G. Localization of ATP-gated P2X2 receptor immunoreactivity in the rat hypothalamus. Brain Res 813, 390-397 (1998).
9. Yang QZ and Hatton GI. Histamine H1-receptor modulation of interneuronal coupling among vasopressinergic neurons depends on nitric oxide synthase activation. Brain Res 955, 115-122 (2002).
10. Hatakeyama S, Kawai Y, Ueyama T and Senba E. Nitric oxide synthase-containing magnocellular neurons of the rat hypothalamus synthesize oxytocin and vasopressin and express Fos following stress stimuli. J Chem Neuroanat 11, 243-256 (1996).
11. Wanaka A, Matsumoto M, Murakami T, Kamada T, Malbon CC and Tohyama M. Immunohistochemical demonstration of beta-adrenoreceptor in the rat brain - with reference to the central control of blood pressure. Clin Exp Hypertens A 10(Suppl 1), 249-255 (1988).
12. Toufexis DJ, Thrivikraman KV, Plotsky PM, Morilak DA, Huang N and Walker CD. Reduced noradrenergic tone to the hypothalamic paraventricular nucleus contributes to the stress hyporesponsiveness of lactation. J Neuroendocrinol 10, 417-427 (1998).
13. Palkovits M. Catecholamines in the hypothalamus: an anatomical review. Neuroendocrinology 33, 123-128 (1981).
14. Obrietan K and van den Pol AN. Calcium hyperexcitability in neurons cultured with glutamate receptor blockade. J Neurophysiol 73, 1524-1536 (1995).
15. Virgili M, Facchinetti F, Sparapani M, Tregnago M, Lucchi R, Dall'Olio R et al. Neuronal nitric oxide synthase is permanently decreased in the cerebellum of rats subjected to chronic neonatal blockade of N-methyl-D-aspartate receptors. Neurosci Lett 258, 1-4 (1998).