Regioselective quinazolinone-directed ortho lithiation of quinazolinoylquinoline: Practical synthesis of naturally occurring human DNA topoisomerase I poison luotonin A and luotonins B and E

Journal of Organic Chemistry

Volumn 69, Issue 13, 2004, Pages 4563-4566

  Mhaske, Santosh B ^a   Argade, Narshinha P ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENZYMES; FORMALDEHYDE; METHANOL; SYNTHESIS (CHEMICAL);

LITHIATION; METHYLATION; QUINOLINE MOIETY;

KETONES;

DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; LUOTONIN A; LUOTONIN B; LUOTONIN E; QUINAZOLINONE DERIVATIVE; QUINAZOLINOYLQUINOLINE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; LITHIATION; MITSUNOBU REACTION; REACTION ANALYSIS; SYNTHESIS;

DNA TOPOISOMERASES, TYPE I; ENZYME INHIBITORS; HUMANS; LITHIUM; MOLECULAR STRUCTURE; PYRROLES; QUINAZOLINES; QUINONES; STEREOISOMERISM;

EID: 3042698774     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo040153v     Document Type: Article

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