메뉴 건너뛰기




Volumn 29, Issue 9, 2004, Pages 1101-1108

Impaired hypothalamic-pituitary-adrenocortical (HPA) system is related to severity of benzodiazepine withdrawal in patients with depression

Author keywords

Benzodiazepine withdrawal; Cortisol; Depression; DEX CRH test; Hypothalamic pituitary adrenocortical system

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE; BROMAZEPAM; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; DIAZEPAM; HYDROCORTISONE; LITHIUM; LORAZEPAM; OXCARBAZEPINE;

EID: 3042687907     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2003.11.004     Document Type: Article
Times cited : (26)

References (45)
  • 1
    • 0021201239 scopus 로고
    • Effects of lormetazepam and of flurazepam on sleep
    • Adam K., Oswald I. Effects of lormetazepam and of flurazepam on sleep. Br. J. Clin. Pharmacol. 17:1984;531-538
    • (1984) Br. J. Clin. Pharmacol. , vol.17 , pp. 531-538
    • Adam, K.1    Oswald, I.2
  • 2
    • 0010833462 scopus 로고
    • Diagnostic and Statistical Manual of Mental Disorders
    • Washington, DC: American Psychiatric Press
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. 1994;American Psychiatric Press, Washington, DC
    • (1994) 4th Ed.
  • 4
    • 0033337584 scopus 로고    scopus 로고
    • The inhibitory effect of alprazolam, a benzodiazepine, overrides the stimulatory effect of metyrapone-induced lack of negative cortisol feedback on corticotroph secretion in humans
    • Arvat E., Maccagno B., Ramunni J., Di Vito L., Giordano R., Gianotti L., Broglio F., Camanni F., Ghigo E. The inhibitory effect of alprazolam, a benzodiazepine, overrides the stimulatory effect of metyrapone-induced lack of negative cortisol feedback on corticotroph secretion in humans. J Clin. Endocrinol. Metab. 84:1999;2611-2615
    • (1999) J Clin. Endocrinol. Metab. , vol.84 , pp. 2611-2615
    • Arvat, E.1    MacCagno, B.2    Ramunni, J.3    Di Vito, L.4    Giordano, R.5    Gianotti, L.6    Broglio, F.7    Camanni, F.8    Ghigo, E.9
  • 8
    • 0026541479 scopus 로고
    • Benzodiazepine-induced sedation and cortisol suppression. A placebo-controlled comparison of oxazepam and nitrazepam in healthy male volunteers
    • Christensen P., Lolk A., Gram L.F., Kragh-Sorensen P. Benzodiazepine-induced sedation and cortisol suppression. A placebo-controlled comparison of oxazepam and nitrazepam in healthy male volunteers. Psychopharmacology (Berl). 106:1992;511-516
    • (1992) Psychopharmacology (Berl) , vol.106 , pp. 511-516
    • Christensen, P.1    Lolk, A.2    Gram, L.F.3    Kragh-Sorensen, P.4
  • 9
    • 0024523844 scopus 로고
    • Cortisol and treatment of depression: Predictive value of spontaneous and suppressed cortisol levels and course of spontaneous plasma cortisol
    • Christensen P., Lolk A., Gram L.F., Kragh-Sorensen P., Pedersen O.L., Nielsen S. Cortisol and treatment of depression: predictive value of spontaneous and suppressed cortisol levels and course of spontaneous plasma cortisol. Psychopharmacology (Berl). 97:1989;471-475
    • (1989) Psychopharmacology (Berl) , vol.97 , pp. 471-475
    • Christensen, P.1    Lolk, A.2    Gram, L.F.3    Kragh-Sorensen, P.4    Pedersen, O.L.5    Nielsen, S.6
  • 11
    • 0031417418 scopus 로고    scopus 로고
    • CRF/NPY interactions: A potential role in sleep dysregulation in depression and anxiety
    • Ehlers C.L., Somes C., Seifritz E., Rivier J.E. CRF/NPY interactions: a potential role in sleep dysregulation in depression and anxiety. Depress. Anxiety. 6:1997;1-9
    • (1997) Depress. Anxiety , vol.6 , pp. 1-9
    • Ehlers, C.L.1    Somes, C.2    Seifritz, E.3    Rivier, J.E.4
  • 12
    • 0035025922 scopus 로고    scopus 로고
    • Is antidepressant-benzodiazepine combination therapy clinically more useful? a meta-analytic study
    • Furukawa T.A., Streiner D.L., Young L.T. Is antidepressant-benzodiazepine combination therapy clinically more useful? A meta-analytic study. J. Affect. Disord. 65:2001;173-177
    • (2001) J. Affect. Disord. , vol.65 , pp. 173-177
    • Furukawa, T.A.1    Streiner, D.L.2    Young, L.T.3
  • 14
    • 0022631967 scopus 로고
    • Benzodiazepine suppression of cortisol secretion: A measure of anxiolytic activity?
    • Gram L.F., Christensen P. Benzodiazepine suppression of cortisol secretion: a measure of anxiolytic activity? Pharmacopsychiatry. 19:1986;19-22
    • (1986) Pharmacopsychiatry , vol.19 , pp. 19-22
    • Gram, L.F.1    Christensen, P.2
  • 15
    • 0036774434 scopus 로고    scopus 로고
    • The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans
    • Grottoli S., Giordano R., Maccagno B., Pellegrino M., Ghigo E., Arvat E. The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans. J. Clin. Endocrinol. Metab. 87:2002;4616-4620
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 4616-4620
    • Grottoli, S.1    Giordano, R.2    MacCagno, B.3    Pellegrino, M.4    Ghigo, E.5    Arvat, E.6
  • 18
    • 0030870660 scopus 로고    scopus 로고
    • Corticotropin-releasing factor CRF1, but not CRF2, receptors mediate anxiogenic-like behavior
    • Heinrichs S.C., Lapsansky J., Lovenberg T.W., De Souza E.B., Chalmers D.T. Corticotropin-releasing factor CRF1, but not CRF2, receptors mediate anxiogenic-like behavior. Regul. Pept. 71:1997;15-21
    • (1997) Regul. Pept. , vol.71 , pp. 15-21
    • Heinrichs, S.C.1    Lapsansky, J.2    Lovenberg, T.W.3    De Souza, E.B.4    Chalmers, D.T.5
  • 19
    • 0027988726 scopus 로고
    • The combined dexamethasone/CRH test: A refined laboratory test for psychiatric disorders
    • Heuser I., Yassouridis A., Holsboer F. The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. J. Psychiatr. Res. 28:1994;341-356
    • (1994) J. Psychiatr. Res. , vol.28 , pp. 341-356
    • Heuser, I.1    Yassouridis, A.2    Holsboer, F.3
  • 20
    • 0030029615 scopus 로고    scopus 로고
    • Pituitary-adrenal-system regulation and psychopathology during amitriptyline treatment in elderly depressed patients and normal comparison subjects
    • Heuser I.J., Schweiger U., Gotthardt U., Schmider J., Lammers C.H., Dettling M., Yassouridis A., Holsboer F. Pituitary-adrenal-system regulation and psychopathology during amitriptyline treatment in elderly depressed patients and normal comparison subjects. Am. J. Psychiatry. 153:1996;93-99
    • (1996) Am. J. Psychiatry. , vol.153 , pp. 93-99
    • Heuser, I.J.1    Schweiger, U.2    Gotthardt, U.3    Schmider, J.4    Lammers, C.H.5    Dettling, M.6    Yassouridis, A.7    Holsboer, F.8
  • 21
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology. 23:2000;477-501
    • (2000) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 22
    • 0023749351 scopus 로고
    • Effects of intravenous corticotropin-releasing hormone upon sleep-related growth hormone surge and sleep EEG in man
    • Holsboer F., von Bardeleben U., Steiger A. Effects of intravenous corticotropin-releasing hormone upon sleep-related growth hormone surge and sleep EEG in man. Neuroendocrinology. 48:1988;32-38
    • (1988) Neuroendocrinology , vol.48 , pp. 32-38
    • Holsboer, F.1    Von Bardeleben, U.2    Steiger, A.3
  • 23
    • 0023086315 scopus 로고
    • Serial assessment of corticotropin-releasing hormone response after dexamethasone in depression. Implications for pathophysiology of DST nonsuppression
    • Holsboer F., von Bardeleben U., Wiedemann K., Muller O.A., Stalla G.K. Serial assessment of corticotropin-releasing hormone response after dexamethasone in depression. Implications for pathophysiology of DST nonsuppression. Biol. Psychiatry. 22:1987;228-234
    • (1987) Biol. Psychiatry , vol.22 , pp. 228-234
    • Holsboer, F.1    Von Bardeleben, U.2    Wiedemann, K.3    Muller, O.A.4    Stalla, G.K.5
  • 24
    • 0025305415 scopus 로고
    • In vitro and in vivo effects of the triazolobenzodiazepine alprazolam on hypothalamic-pituitary-adrenal function: Pharmacological and clinical implications
    • Kalogeras K.T., Calogero A.E., Kuribayiashi T., Khan I., Gallucci W.T., Kling M.A., Chrousos G.P., Gold P.W. In vitro and in vivo effects of the triazolobenzodiazepine alprazolam on hypothalamic-pituitary-adrenal function: pharmacological and clinical implications. J. Clin. Endocrinol. Metab. 70:1990;1462-1471
    • (1990) J. Clin. Endocrinol. Metab. , vol.70 , pp. 1462-1471
    • Kalogeras, K.T.1    Calogero, A.E.2    Kuribayiashi, T.3    Khan, I.4    Gallucci, W.T.5    Kling, M.A.6    Chrousos, G.P.7    Gold, P.W.8
  • 25
    • 0037251858 scopus 로고    scopus 로고
    • The high-affinity non-peptide CRH1 receptor antagonist R121919 attenuates stress-induced alterations in plasma oxytocin, prolactin and testosterone secretion in rats
    • Keck M.E., Welt T., Muller M.B., Landgraf R., Holsboer F. The high-affinity non-peptide CRH1 receptor antagonist R121919 attenuates stress-induced alterations in plasma oxytocin, prolactin and testosterone secretion in rats. Pharmacopsychiatry. 36:2003;27-31
    • (2003) Pharmacopsychiatry , vol.36 , pp. 27-31
    • Keck, M.E.1    Welt, T.2    Muller, M.B.3    Landgraf, R.4    Holsboer, F.5
  • 26
    • 0035122647 scopus 로고    scopus 로고
    • The anxiolytic effect of the CRH(1) receptor antagonist R121919 depends on innate emotionality in rats
    • Keck M.E., Welt T., Wigger A., Renner U., Engelmann M., Holsboer F., Landgraf R. The anxiolytic effect of the CRH(1) receptor antagonist R121919 depends on innate emotionality in rats. Eur. J. Neurosci. 13:2001;373-380
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 373-380
    • Keck, M.E.1    Welt, T.2    Wigger, A.3    Renner, U.4    Engelmann, M.5    Holsboer, F.6    Landgraf, R.7
  • 27
    • 0036147367 scopus 로고    scopus 로고
    • Vasopressin mediates the response of the combined dexamethasone/CRH test in hyper-anxious rats: Implications for pathogenesis of affective disorders
    • Keck M.E., Wigger A., Welt T., Muller M.B., Gesing A., Reul J.M., Holsboer F., Landgraf R., Neumann I.D. Vasopressin mediates the response of the combined dexamethasone/CRH test in hyper-anxious rats: implications for pathogenesis of affective disorders. Neuropsychopharmacology. 26:2002;94-105
    • (2002) Neuropsychopharmacology , vol.26 , pp. 94-105
    • Keck, M.E.1    Wigger, A.2    Welt, T.3    Muller, M.B.4    Gesing, A.5    Reul, J.M.6    Holsboer, F.7    Landgraf, R.8    Neumann, I.D.9
  • 28
    • 0028973118 scopus 로고
    • Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats
    • Liebsch G., Landgraf R., Gerstberger R., Probst J.C., Wotjak C.T., Engelmann M., Holsboer F., Montkowski A. Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats. Regul. Pept. 59:1995;229-239
    • (1995) Regul. Pept. , vol.59 , pp. 229-239
    • Liebsch, G.1    Landgraf, R.2    Gerstberger, R.3    Probst, J.C.4    Wotjak, C.T.5    Engelmann, M.6    Holsboer, F.7    Montkowski, A.8
  • 29
    • 0022976272 scopus 로고
    • Withdrawal syndrome with gradual tapering of alprazolam
    • Mellman T.A., Uhde T.W. Withdrawal syndrome with gradual tapering of alprazolam. Am. J. Psychiatry. 143:1986;1464-1466
    • (1986) Am. J. Psychiatry. , vol.143 , pp. 1464-1466
    • Mellman, T.A.1    Uhde, T.W.2
  • 30
    • 0031027742 scopus 로고    scopus 로고
    • Corticosteroid receptor function is decreased in depressed patients
    • Modell S., Yassouridis A., Huber J., Holsboer F. Corticosteroid receptor function is decreased in depressed patients. Neuroendocrinology. 65:1997;216-222
    • (1997) Neuroendocrinology , vol.65 , pp. 216-222
    • Modell, S.1    Yassouridis, A.2    Huber, J.3    Holsboer, F.4
  • 31
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery S.A., Asberg M. A new depression scale designed to be sensitive to change. Br. J. Psychiatry. 134:1979;382-389
    • (1979) Br. J. Psychiatry. , vol.134 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 34
    • 0025895457 scopus 로고
    • The effects of alprazolam on corticotropin-releasing factor neurons in the rat brain: Acute time course, chronic treatment and abrupt withdrawal
    • Owens M.J., Vargas M.A., Knight D.L., Nemeroff C.B. The effects of alprazolam on corticotropin-releasing factor neurons in the rat brain: acute time course, chronic treatment and abrupt withdrawal. J. Pharmacol. Exp. Ther. 258:1991;349-356
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 349-356
    • Owens, M.J.1    Vargas, M.A.2    Knight, D.L.3    Nemeroff, C.B.4
  • 35
    • 0027753019 scopus 로고
    • The effects of alprazolam on corticotropin-releasing factor neurons in the rat brain: Implications for a role for CRF in the pathogenesis of anxiety disorders
    • Owens M.J., Vargas M.A., Nemeroff C.B. The effects of alprazolam on corticotropin-releasing factor neurons in the rat brain: implications for a role for CRF in the pathogenesis of anxiety disorders. J. Psychiatr. Res. 27:(suppl. 1):1993;209-220
    • (1993) J. Psychiatr. Res. , vol.27 , Issue.SUPPL. 1 , pp. 209-220
    • Owens, M.J.1    Vargas, M.A.2    Nemeroff, C.B.3
  • 36
    • 0028216999 scopus 로고
    • The stress-, but not corticotropin-releasing hormone-induced activation of the pituitary-adrenal axis in man is blocked by alprazolam
    • Rohrer T., von R.V., Schulz C., Beyer J., Lehnert H. The stress-, but not corticotropin-releasing hormone-induced activation of the pituitary-adrenal axis in man is blocked by alprazolam. Horm. Metab. Res. 26:1994;200-206
    • (1994) Horm. Metab. Res. , vol.26 , pp. 200-206
    • Rohrer, T.1    Von R., V.2    Schulz, C.3    Beyer, J.4    Lehnert, H.5
  • 37
    • 0031722787 scopus 로고    scopus 로고
    • Benzodiazepine dependence and withdrawal: A review of the syndrome and its clinical management
    • Schweizer E., Rickels K. Benzodiazepine dependence and withdrawal: a review of the syndrome and its clinical management. Acta Psychiatr. Scand. Suppl. 393:1998;95-101
    • (1998) Acta Psychiatr. Scand. Suppl. , vol.393 , pp. 95-101
    • Schweizer, E.1    Rickels, K.2
  • 38
    • 0034143267 scopus 로고    scopus 로고
    • Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems
    • Skelton K.H., Nemeroff C.B., Knight D.L., Owens M.J. Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems. J. Neurosci. 20:2000;1240-1248
    • (2000) J. Neurosci. , vol.20 , pp. 1240-1248
    • Skelton, K.H.1    Nemeroff, C.B.2    Knight, D.L.3    Owens, M.J.4
  • 40
    • 0028625387 scopus 로고
    • Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats
    • Skutella T., Montkowski A., Stohr T., Probst J.C., Landgraf R., Holsboer F., Jirikowski G.F. Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats. Cell Mol. Neurobiol. 14:1994;579-588
    • (1994) Cell Mol. Neurobiol. , vol.14 , pp. 579-588
    • Skutella, T.1    Montkowski, A.2    Stohr, T.3    Probst, J.C.4    Landgraf, R.5    Holsboer, F.6    Jirikowski, G.F.7
  • 43
    • 0021857125 scopus 로고
    • Combined administration of human corticotropin-releasing factor and lysine vasopressin induces cortisol escape from dexamethasone suppression in healthy subjects
    • von Bardeleben U., Holsboer F., Stalla G.K., Muller O.A. Combined administration of human corticotropin-releasing factor and lysine vasopressin induces cortisol escape from dexamethasone suppression in healthy subjects. Life Sci. 37:1985;1613-1618
    • (1985) Life Sci. , vol.37 , pp. 1613-1618
    • Von Bardeleben, U.1    Holsboer, F.2    Stalla, G.K.3    Muller, O.A.4
  • 44
    • 0034993647 scopus 로고    scopus 로고
    • Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression. A prospective study
    • Zobel A.W., Nickel T., Sonntag A., Uhr M., Holsboer F., Ising M. Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression. a prospective study. J. Psychiatr. Res. 35:2001;83-94
    • (2001) J. Psychiatr. Res. , vol.35 , pp. 83-94
    • Zobel, A.W.1    Nickel, T.2    Sonntag, A.3    Uhr, M.4    Holsboer, F.5    Ising, M.6
  • 45
    • 0033012264 scopus 로고    scopus 로고
    • Prediction of medium-term outcome by cortisol response to the combined dexamethasone-CRH test in patients with remitted depression
    • Zobel A.W., Yassouridis A., Frieboes R.M., Holsboer F. Prediction of medium-term outcome by cortisol response to the combined dexamethasone-CRH test in patients with remitted depression. Am. J. Psychiatry. 156:1999;949-951
    • (1999) Am. J. Psychiatry. , vol.156 , pp. 949-951
    • Zobel, A.W.1    Yassouridis, A.2    Frieboes, R.M.3    Holsboer, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.