Modulation of the response to estradiol-17β of rat vascular tissues by a non calcemic vitamin D analog

Journal of Steroid Biochemistry and Molecular Biology

Volumn 89-90, Issue , 2004, Pages 339-341

  Somjen, Dalia ^a   Katzburg, Sara ^a   Baz, Merav ^a   Stern, Naftali ^a   Posner, Gary H ^b  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

"Non hypercalcemic" vitamin D analogs; Creatine kinase; Estrogen; Estrogen receptors and

Indexed keywords

CREATINE KINASE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; JK 1624 F2 2; RALOXIFENE; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; HEART LEFT VENTRICLE; HORMONE RESPONSE; NONHUMAN; RAT; REGULATORY MECHANISM; UPREGULATION; VASCULAR TISSUE;

ANIMALS; AORTA; CALCITRIOL; ESTRADIOL; FEMALE; HEART VENTRICLES; RATS; RATS, WISTAR;

ANIMALIA;

EID: 3042687356     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2004.03.022     Document Type: Conference Paper

References (17)

1. Hays J., Ockrene J.K., Brunner R.L., Kotchen J.M., Manson J.A.E., Patterson R.E., Aragaki A.K., Shumaker S.A., Bryski R.G., LaCroix A.Z., Granek I.A., Valanis B.G. Effects of estrogen plus progestin on health-related quality of life. New Engl. J. Med. 348:2003;1839-1854
2. Iafrati M.D., Karas R.H., Aronovitz M., Kim S., Sullivan T.R. Jr., Lubahn D.B., O'Donnell T.F. Jr., Korach K.S., Mendelsohn M.E. Estrogen inhibits the vascular injury response in estrogen receptor alpha-deficient mice. Nat Med. 3:1997;545-548
3. Seed M. Sex hormones, lipoproteins, and cardiovascular risk. Atherosclerosis. 90:1991;1-7
4. Sourander L., Rajala T., Raiha I., Makinen J., Erkkola R., Helenius H. Cardiovascular and cancer morbidity and mortality and sudden cardiac death in postmenopausal women on estrogen replacement therapy (ERT). Lancet. 352:1998;1965-1969
5. Shewmon D.A., Stock J.L., Rosen C.J., Heiniluoma K.M., Hogue M.M., Morrison A., Doyle E.M., Ukena T., Weale V., Baker S. Tamoxifen and estrogen lower circulating lipoprotein (a) concentrations in healthy postmenopausal women. Arterioscler Thromb. 14:1994;1586-1593
6. Kapiotis S., Hermann M., Held I. Genistein, and the dietary-derived angiogenesis inhibitor, prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL. Arterioscler. Thromb. Vasc. Biol. 17:1997;2868-2874
7. Honore E.K., Williams J.K., Anthony M.S., Clarkson T.B. Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques. Fertil. Steril. 67:1997;148-154
8. Lissin L.W., Cooke J.P. Phytoestrogens and cardiovascular health. J. Am. Coll. Cardiol. 35:2000;1403-1410
9. Hodges Y.K., Tung L., Yan X.D. Estrogen receptors alpha and beta: prevalence of estrogen receptor beta mRNA in human vascular smooth muscle and transcriptional effects. Circulation. 101:2000;1792-1798
10. Iafrati M.D., Karas R.H., Aronovitz M. Estrogen inhibits the vascular injury response in estrogen receptor alpha-deficient mice. Nat. Med. 3:1997;545-548
11. Malnick S.D., Shaer A., Soreq H., Kaye A.M. Estrogen-induced creatine kinase in the reproductive system of the immature female rat. Endocrinology. 113:1983;1907-1909
12. Somjen D., Waisman A., Weisman J., Kaye A.M. Non hypercalcemic analogs of vitamin D stimulate creatine kinase B activity in osteoblast-like ROS 17/2.8 cells and up-regulate their responsiveness to estrogens. Steroids. 63:1998;340-343
13. 3. Synthesis and preliminary biological evaluation. J. Med. Chem. 41:1998;3008-3014
14. 3 (JKF) upregulates the induction of creatine kinase B by 17β estradiol in osteoblast-like ROS 17/2.8 cells and in rat diaphysis. J. Steroid Biochem. Mol. Biol. 77:2001;205-212
15. Somjen D., Kohen F., Amir- Zaltsman Y., Knoll E., Stern N. Vitamin D analogs modulate the action of gonadal steroids in human vascular cells in vitro. Am. J. Hypertens. 13:2000;396-404
16. Somjen D., Weisman Y., Harell A., Berger E., Kaye A.M. Direct and sex-specific stimulation by sex steroids of creatine kinase activity and DNA synthesis in rat bone. Proc. Natl. Acad. Sci. U.S.A. 86:1998;3361-3365
17. Somjen D., Waisman A., Kaye A.M. Tissue selective action of tamoxifen methiodide, raloxifene and tamoxifen on creatine kinase B activity in vitro and in vivo. J. Steroid Biochem. Mol. Biol. 59:1996;389-396