The Plasmodium falciparum Vps4 homolog mediates multivesicular body formation

Journal of Cell Science

Volumn 117, Issue 17, 2004, Pages 3831-3838

  Yang, Mei ^a   Coppens, Isabelle ^a   Wormsley, Steve ^a   Baevova, Pavlina ^a   Hoppe, Heinrich C ^a   Joiner, Keith A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cholesterol; Endosome; Multivesicular body; Plasmodium; Rhoptry; Toxoplasma

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CHOLESTEROL; PROTEIN VPS4; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

APICOMPLEXA; ARTICLE; BINDING KINETICS; CELL STRAIN COS1; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; ENDOSOME; GENE EXPRESSION; GENE LOCATION; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; MOLECULAR PROBE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE DEVELOPMENT; PHYLOGENY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; SECRETORY VESICLE; TOXOPLASMA GONDII; TROPHOZOITE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; CELL PROLIFERATION; CHOLESTEROL; CLONING, MOLECULAR; COS CELLS; CYTOPLASM; CYTOSOL; DNA; ELECTROPORATION; ENDOSOMES; FIBROBLASTS; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROLYSIS; IMMUNOBLOTTING; LIPOPROTEINS, LDL; MICROSCOPY, ELECTRON; MUTATION; PHYLOGENY; PLASMODIUM FALCIPARUM; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; SUBCELLULAR FRACTIONS; TOXOPLASMA; TRANSFECTION; TRANSGENES;

APICOMPLEXA; PLASMODIUM FALCIPARUM; PROTOZOA; TOXOPLASMA; TOXOPLASMA GONDII;

EID: 3042667972     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01237     Document Type: Article

References (32)

1. Babst, M., Sato, T. K., Banta, L. M. and Emr, S. D. (1997). Endosomal transport function in yeast requires a novel AAA-type ATPase, Yps4p. EMBO J. 16, 1820-1831.
2. Babst, M., Wendland, B., Estepa, E. J. and Emr, S. D. (1998). The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J. 17, 2982-2993.
3. Bahl, A., Brunk, B., Coppel, R. L., Crabtree, J., Diskin, S. J., Fraunholz, M. J., Grant, G. R., Gupta, D., Huestis, R. L., Kissinger, J. C. et al. (2002). PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished). Nucleic Acids Res. 30, 87-90.
4. Bannister, L. H., Mitchell, G. H., Butcher, G. A. and Dennis, E. D. (1986). Lamellar membranes associated with rhoptries in erythourocyte merozoites of Plasmodium knowlesi: a clue to the mechanism of invasion. Parasitology 92, 291-303.
5. Beckers, C. J. M., Wakefield, T., Dubey, J. P. and Joiner, K. A. (1997). The expression of Toxoplasma proteins in Neospora caninum and the identification of a gene encoding a novel rhoptry protein. Mol. Biochem. Parasitol. 89, 209-223.
6. Bishop, N. and Woodman, P. (2000). ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking. Mol. Biol. Cell 11, 227-239.
7. Blott, E. J. and Griffiths, G. M. (2002). Secretory lysosomes. Nat. Rev. Mol. Cell Biol. 3, 122-131.
8. Conibear, E. (2002). An ESCRT into the endosome. Mol. Cell 10, 215-216.
9. Coppens, I. and Joiner, K. A. (2003). Host but not parasite cholesterol controls Toxoplasma entry by modulating organelle discharge. Mol. Biol. Cell 14, 3804-3820.
10. Crabb, B. S., Triglia, T., Waterkeyn, J. G. and Cowman, A. F. (1997). Stable transgene expression in Plasmodium falciparum. Mol. Biochem. Parasitol. 90, 131-144.
11. Deitsch, K., Driskill, C. and Wellems, T. (2001). Transformation of malaria parasites by the spontaneous uptake and expression of DNA from human erythourocytes. Nucleic Acids Res. 29, 850-853.
12. Donald, R. G. K. and Roos, D. S. (1993). Stable molecular transformation of Toxoplasma gondii: a selectable dihydrofolate reductase-thymidylate synthase marker based on drug resistance mutations in malaria. Proc. Natl. Acad. Sci. USA 90, 11703-11707.
13. El-Jack, A. K., Kandror, K. V. and Pilch, P. F. (1999). The formation of an insulin-responsive vesicular cargo compartment is an early event in 3T3-L1 adipocyte differentiation. Mol. Biol. Cell 10, 1584-1594.
14. Fidock, D. A. and Wellems, T. E. (1987). Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Proc. Natl. Acad. Sci. USA 94, 10931-10936.
15. Folsch, H., Pypaert, M., Schu, P. and Mellman, I. (2001). Distribution and function of AP-1 clathrin adaptor complexes in polarized epithelial cells. J. Cell Biol. 152, 595-606.
16. Foussard, F., Leriche, M. A. and Dubremetz, J. F. (1991). Characterization of the lipid content of Toxoplasma gondii rhoptries. Parasitology 102, 367-370.
17. Hoppe, H. C., Ngo, H. M., Yang, M. and Joiner, K. A. (2000). Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms. Nat. Cell. Biol. 2, 449-456.
18. Jiang, L., Erickson, A. and Rogers, J. (2092). Multivesicular bodies: a mechanism to package lytic and storage functions in one organelle? Trends Cell. Biol. 12, 362-367.
19. Joiner, K. A. and Roos, D. S. (2002). Secretory traffic in the eukaryotic parasite Toxoplasma gondii: less is more. J. Cell Biol. 157, 557-563.
20. Karsten, V., Qi, H., Beckers, C. J. M. and Joiner, K. A. (1997). Targeting the secretory pathway of Toxoplasma gondii. Methods 13, 103-111.
21. Kissinger, J. C., Brunk, B. P., Crabtree, J., Fraunholz, M. J., Gajria, B., Milgram, A. J., Pearson, D. S., Schug, J., Bahl, A., Diskin, S. J. et al. (2002). The Plasmodium genome database. Nature 419, 490-492.
22. Ngô, H. M., Yang, M., Pypaert, M., Hoppe, H. C. and Joiner, K. A. (2003). Biogenesis of secretory organelles in an apicomplexan parasite is dependent on the AP-1 adaptin. J. Biol. Chem. 278, 5343-5352.
23. Odorizzi, G., Babst, M. and Emr, S. D. (1998). Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell 95, 847-858.
24. Piper, R. C. and Luzio, J. P. (2001). Late endosomes: sorting and partitioning in multivesicular bodies, Traffic 2, 612-621.
25. Que, X., Ngo, H., Lawton, J., Gray, M., Liu, Q., Engel, J., Brinen, L., Ghosh, P., Joiner, K. A. and Reed, S. L. (2002). The cathepsin B of Toxoplasma gondii, toxopain-1, is critical for parasite invasion and rhoptry protein processing. J. Biol. Chem. 277, 25791-25797.
26. Raymond, C. K., Howald-Stevenson, I., Vater, C. A. and Stevens, T. H. (1992). Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol. Biol. Cell 3, 1389-1402
27. Robibaro, B., Stedman, T. T., Coppens, I., Ngo, H. M., Pypaert, M., Bivona, T., Nam, H. W. and Joiner, K. A. (2002). Toxoplasma gondii Rab5 enhances cholesterol acquisition from host cells. Cell. Microbiol. 4, 139-152.
28. Roos, D. S., Donald, R. G. K., Morrissette, N. S. and Moulton, A. L. C. (1994). Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii. Methods Cell Biol. 45, 27-63.
29. Stoorvogel, W., Kleijmeer, M. J., Geuze, H. J. and Raposo, G. (2002). The biogenesis and functions of exosomes. Traffic 3, 321-330.
30. Teter, S. A. and Klionsky, D. J. (2000). Transport of proteins to the yeast vacuole: autophagy, cytoplasm-to-vacuole targeting, and role of the vacuole in degradation. Semin. Cell Dev. Biol. 11, 173-179.
31. Valdivia, R. H., Baggott, D., Chuang, J. S. and Schekman, R. W. (2002). The yeast clathourin adaptor protein complex 1 is required for the efficient retention of a subset of late Golgi membrane proteins. Dev. Cell 2, 283-294.
32. Vielemeyer, O., McIntosh, M. T., Joiner, K. A. and Coppens, I. (2004). Neutral lipid synthesis and storage in the intraerythourocytic stages of Plasmodium falciparum. Mol. Biochem. Parasitol. 135, 197-209.