Conjugates of gadolinium complexes to bile acids as hepatocyte-directed contrast agents for magnetic resonance imaging

Journal of Medicinal Chemistry

Volumn 47, Issue 14, 2004, Pages 3629-3641

  Anelli, Pier Lucio ^a   Lattuada, Luciano ^a   Lorusso, Vito ^a   Lux, Giovanna ^a   Morisetti, Alberto ^a   Morosini, Pierfrancesco ^a   Serleti, Michele ^a   Uggeri, Fulvio ^a  

^a Bracco Imaging SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; BILE ACID; CARBOXYL GROUP; CARBOXYLIC ACID DERIVATIVE; CHELATING AGENT; CHOLIC ACID; CHOLIC ACID DERIVATIVE; CHOLYLLYSINE; CONTRAST MEDIUM; GADOLINIUM; GADOLINIUM PENTETATE; GADOTERIC ACID; GLYCOCHOLIC ACID; HYDROXYL GROUP; LIGAND; LYSINE DERIVATIVE; NITROGEN; PENTETIC ACID; STEROID; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BILIARY EXCRETION; CONJUGATE; CONTROLLED STUDY; DRUG SAFETY; DRUG TOLERABILITY; DRUG TRANSPORT; FEMALE; LD 50; LIVER CELL; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT; STRUCTURE ANALYSIS;

ANIMALS; BILE ACIDS AND SALTS; CHELATING AGENTS; CONTRAST MEDIA; FEMALE; GADOLINIUM; HEMODYNAMIC PHENOMENA; HEPATOCYTES; HETEROCYCLIC COMPOUNDS, 1-RING; LETHAL DOSE 50; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED ICR; ORGANOMETALLIC COMPOUNDS; PENTETIC ACID; RABBITS; RATS;

EID: 3042643035     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0310683     Document Type: Article

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