The generation of neural stem cells: Induction of neural stem cells from embryonic stem (ES) cells

Clinical Neurology

Volumn 43, Issue 11, 2003, Pages 827-829

  Hitoshi, Seiji ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Embryonic stem cell; Neural stem cell; Notch signaling; Primitive neural stem cell

Indexed keywords

LEUKEMIA INHIBITORY FACTOR; NOTCH RECEPTOR;

ANIMAL CELL; CONFERENCE PAPER; ECTODERM; EMBRYO; EMBRYO CELL; INNER CELL MASS; MOUSE; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYO; FETAL TISSUE TRANSPLANTATION; HUMANS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; MEMBRANE PROTEINS; MICE; MULTIPOTENT STEM CELLS; NEURONS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL;

EID: 3042637106     PISSN: 0009918X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (6)

1. Tropepe V, Hitoshi S, Sirard C, et al: Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 2001; 30: 65-78
2. Smith A: Embryonic stem cells. In stem cell biology. ed by Marshank DR, Gardner RL, Gottlieb D, Cold Spring Harbor Laboratory Press, New York, 2001, pp205-230
3. Lee SH, Lumelsky N, Studer L, et al: Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 2000; 18: 675-679
4. Tropepe V, Sibilia M, Ciruna BG, et al: Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev Biol 1999; 208: 166-188
5. Gaiano N, Nye JS, Fishell G: Radial glial identity is promoted by Notchl signaling in the murine forebrain. Neuron 2000; 26: 395-404
6. Hitoshi S, Alexson T, Tropepe V, et al: Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes & Dev 2002; 16: 846-858