Vitamin D antagonist, TEI-9647, inhibits osteoclast formation induced by 1α,25-dihydroxyvitamin D3 from pagetic bone marrow cells

Journal of Steroid Biochemistry and Molecular Biology

Volumn 89-90, Issue , 2004, Pages 331-334

  Ishizuka, Seiichi ^a,b   Kurihara, Noriyoshi ^b   Miura, Daishiro ^a   Takenouchi, Kazuya ^a   Cornish, Jillian ^c   Cundy, Tim ^c   Reddy, Sakamuri V ^b   Roodman, G David ^b,d  

^a TEIJIN LTD   (Japan)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Bone resorption; Coactivator; Measles virus; Osteoclast; Paget's disease; Vitamin D antagonist; Vitamin D receptor

Indexed keywords

25 DEHYDRO 1ALPHA HYDROXYVITAMIN D3 26,23 LACTONE; CALCITRIOL; COLONY STIMULATING FACTOR 1; LACTONE DERIVATIVE; OSTEOCLAST DIFFERENTIATION FACTOR; TEI 9647; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

BONE MARROW CELL; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEUKEMIA CELL; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOLYSIS; PAGET BONE DISEASE;

BASE SEQUENCE; BONE MARROW CELLS; BONE RESORPTION; CALCITRIOL; DNA PRIMERS; GENE EXPRESSION REGULATION; HUMANS; OSTEITIS DEFORMANS; OSTEOCLASTS; VITAMIN D;

MEASLES VIRUS;

EID: 3042600952     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2004.03.025     Document Type: Conference Paper

References (6)

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3. 3 responsivity of osteoclast (OCL) precursors from Paget's disease. J. Bone Miner. Res. 17(suppl 1):2002;S380-S389
4. Kukita T., Chenu C., McManus L.M., Mundy G.R., Roodman G.D. A typical multinucleated cells form in long-term marrow cultures from patients with Paget's disease. J. Clin. Invest. 85:1990;1280-1286
5. 3 in human serum. J. Nutr. Sci. Vitam. 27:1981;71-75
6. Reddy S.V., Kurihara N., Menaa C., Landucci G., Forthal D., Koop B.A., Windle J.J., Roodman G.D. Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts. Endocrinology. 142:2001;2898-2905