Comparison in a rat thigh abscess model of imipenem, meropenem and cefoperazone-sulbactam against Acinetobacter baumannii strains in terms of bactericidal efficacy and resistance selection

Annals of Clinical Microbiology and Antimicrobials

Volumn 3, Issue , 2004, Pages

  Fetiye, Kolayli ^a   Karadenizli, Aynur ^a   Okay, Erdem ^a   Oz, Sarpkaya ^a   Budak, Fatma ^a   Gundes, Sibel ^a   Vahaboglu, Haluk ^a  

^a KOCAELI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

IMIPENEM; MEROPENEM; SULPERAZON;

ABSCESS; ACINETOBACTER BAUMANNII; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIUM COLONY; BIOASSAY; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFICACY; MALE; NONHUMAN; RAT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 3042563381     PISSN: 14760711     EISSN: None     Source Type: Journal    
DOI: 10.1186/1476-0711-3-2     Document Type: Article

References (16)

1. Fagon JY, Chastre J, Hance AJ, Montravers P, Novara A, Gibert C: Nosocomial pneumonia in ventilated patients: a cohort study evaluating attributable mortality and hospital stay. Am J Med 1993, 94:281-288.
2. Akca O, Koltka K, Uzel S, Cakar N, Pembeci K, Sayan MA, Tutuncu AS, Karakas SE, Calangu S, Ozkan T, Esen F, Telci L, Sessler DI, Akpir K: Risk factors for early-onset, ventilator-associated pneumonia in critical care patients: selected multiresistant versus nonresistant bacteria. Anesthesiology 2000, 93:638-645.
3. Baraibar J, Correa H, Mariscal D, Gallego M, Valles J, Rello J: Risk factors for infection by Acinetobacter baumannii in intubated patients with nosocomial pneumonia. Chest 1997, 112:1050-1054.
4. Gomez J, Simarro E, Banos V, Requena L, Ruiz J, Garcia F, Canteras M, Valdes M: Six-year prospective study of risk and prognostic factors in patients with nosocomial sepsis caused by Acinetobacter baumannii. Eur J Clin Microbiol Infect Dis 1999, 18:358-361.
5. Hancock RE: Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative gram-negative bacteria. Clin Infect Dis 1998, 27 Suppl 1:S93-9.
6. Bou G, Cervero G, Dominguez MA, Quereda C, Martinez-Beltran J: Characterization of a nosocomial outbreak caused by a multiresistant Acinetobacter baumannii strain with a carbapenem-hydrolyzing enzyme: high-level carbapenem resistance in A. baumannii is not due solely to the presence of beta-lactamases. J Clin Microbiol 2000, 38:3299-3305.
7. Perilli M, Felici A, Oratore A, Cornaglia G, Bonfiglio G, Rossolini GM, Amicosante G: Characterization of the chromosomal cephalosporinases produced by Acinetobacter Iwoffii and Acinetobacter baumannii clinical isolates. Antimicrob Agents Chemother 1996, 40:715-719.
8. Obara M, Nakae T: Mechanisms of resistance to beta-lactam antibiotics in Acinetobacter calcoaceticus. J Antimicrob Chemother 1991, 28:791-800.
9. Livermore DM: Interplay of impermeability and chromosomal beta-lactamase activity in imipenem-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 1992, 36:2046-2048.
10. Chow JW, Fine MJ, Shlaes DM, Quinn JP, Hooper DC, Johnson MP, Ramphal R, Wagener MM, Miyashiro DK, Yu VL: Enterobacter bacteremia: clinical features and emergence of antibiotic resistance during therapy. Ann Intern Med 1991, 115:585-590.
11. Karadenizli A, Mutlu B, Okay E, Kolayli F, Vahaboglu H: Piperacillin with and without tazobactam against extended-spectrum beta-lactamase-producing Pseudomonas aeruginosa in a rat thigh abscess model. Chemotherapy 2001, 47:292-296.
12. Bergogne-Berezin E, Towner KJ: Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin Microbiol Rev 1996, 9:148-165.
13. Sato K, Nakae T: Outer membrane permeability of Acinetobacter calcoaceticus and its implication in antibiotic resistance. J Antimicrob Chemother 1991, 28:35-45.
14. Aksaray S, DokuzoGuz B, Guvener E, Yucesoy M, Yulug N, Kocagoz S, Unal S, Cetin S, Calangu S, Gunaydin M, Leblebicioglu H, Esen S, Bayar B, Willke A, Findik D, Tuncer I, Baysal B, Gunseren F, Mamikoglu L: Surveillance of antimicrobial resistance among gram-negative isolates from intensive care units in eight hospitals in Turkey. J Antimicrob Chemother 2000, 45:695-699.
15. Vahaboglu H, Ozturk R, Aygun G, Coskunkan F, Yaman A, Kaygusuz A, Leblebicioglu H, Balik I, Aydin K, Otkun M: Widespread detection of PER-1-type extended-spectrum beta-lactamases among nosocomial Acinetobacter and Pseudomonas aeruginosa isolates in Turkey: a nationwide multicenter study. Antimicrob Agents Chemother 1997, 41:2265-2269.
16. Wolff M, Joly-Guillou ML, Farinotti R, Carbon C: In vivo efficacies of combinations of beta-lactams, beta-lactamase inhibitors, and rifampin against Acinetobacter baumannii in a mouse pneumonia model. Antimicrob Agents Chemother 1999, 43:1406-1411.