Characterization of the chromosomal cephalosporinases produced by Acinetobacter Iwoffii and Acinetobacter baumannii clinical isolates

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 3, 1996, Pages 715-719

  Perilli, Mariagrazia ^a   Felici, Antonio ^a   Oratore, Arduino ^a   Cornaglia, Giuseppe ^b   Bonfiglio, Giovanni ^c   Rossolini, Gian Maria ^d   Amicosante, Gianfranco ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c UNIVERSITY OF CATANIA   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

6BETA IODOPENICILLANIC ACID; AZTREONAM; BETA LACTAM ANTIBIOTIC; CARBENICILLIN; CEFALORIDINE; CEFALOTIN; CEFOTAXIME; CEFPIROME; CEFTAZIDIME; CEPHALOSPORINASE; CLAVULANIC ACID; IMIPENEM; NITROCEFIN; PENICILLIN G; PIPERACILLIN; SULBACTAM;

ACINETOBACTER; ARTICLE; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME INHIBITION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

ACINETOBACTER; ACINETOBACTER INFECTIONS; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CEPHALOSPORINASE; CHROMOSOMES, BACTERIAL; CLAVULANIC ACID; CLAVULANIC ACIDS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; HUMANS; ISOELECTRIC FOCUSING; KINETICS; MICROBIAL SENSITIVITY TESTS; SULBACTAM;

EID: 0030030554     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.3.715     Document Type: Article

References (27)

1. Bergogne-Berezin, E., and M. I. Joly-Guillou. 1985. An underestimated nosocomial pathogen, Acinetobacter calcoaceticus. J Antimicrob. Chemother 16:535-538.
2. Blechschmidt, B., P. Borneleit, and H.-P. Kleber. 1992. Purification and characterization of an extracellular β-lactamase produced by Acinetobacter calcoaceticus. J Gen. Microbiol. 138:1197-1202.
3. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:248-254.
4. Bush, K., J. S. Freudenberger, and R. B. Sykes. 1982. Interaction of azthreonam and related monobactams with β-lactamases from gram-negative bacteria. Antimicrob. Agents Chemother. 22:414-420.
5. Bush, K., G. A. Jacoby, and A. A. Medeiros. 1995. A functional classification scheme for β-lactamases and its correlation with molecular structure Antimicrob. Agents Chemother. 39:1211-1233.
6. De Meester, F., J.-M. Frère, S. G. Waley, S. J. Cartwright, R. Virden, and F. Lindberg. 1986. 6-β-Iodopenicillanate as a probe for the classification of β-lactamases. Biochem. .T. 239:575-580.
7. De Meester, F., B. Joris, G. Reckinger, C. Bellefroid-Bourguignon, J.-M. Frère, and S. G. Waley. 1987. Automated analysis of enzyme mactivation phenomena. Biochem. Pharmacol. 36:2393-2403.
8. Felici, A., and G. Amicosante. 1995. Kinetic analysis of extension of substrate specificity with Xanthomonas malthophilia, Aeromonas hydrophila, and Bacillus cereus metallo-β-lactamases. Antimicrob. Agents Chemother. 39:192-199.
9. Frère. J.-M., C. Dormans, C. Duyckaerts, and J. De Graeve. 1982. Interaction of 6-β-iodopenicillanate with the β-lactamases of Streptomyces albus G and Actinomadura R39. Biochem. J. 207:437-444.
10. Galleni, M.. G. Amicosante, and J.-M. Frère. 1988. A survey of the kinetic-parameters of class C β-lactamases Cephalosporins and other β-lactam compounds Biochem J 255:123-129
11. Galleni, M., and J.-M. Frère. 1988. A survey of the kinetic parameters of class C β-lactamases. Penicillins Biochem. J 255:119-122
12. Gehrlein, M., H. L. Leying, W. Cullmann, S. Wendt, and W. Opferkuch. 1991. Imipenem resistance in Acinetobacter baumannu is due to altered penicillin-binding protein. Chemotherapy (Basel) 37:405-412.
13. Hikida, M., M. Yoshida, S. Mitsuhashi, and M. Inoue. 1989. Purification and properties of a cephalosporinase from Acinetobacter calcoaceticus. J. Antibiot. 42:123-126.
14. Hood, J., and S. G. B. Amyes. 1991. The chromosomal β-lactamases of the genus Acinetobacter: enzymes which challenge our imagination, p. 117-132. In K. J. Towner (ed.). The biology of Acinetobacter. Plenum Press. New York.
15. Joly-Guillou, M. L., E. Bergogne-Berezin, and N. Moreau. 1987. Enzymatic resistance to β-lactams and aminoglycosides in Acinetobacter calcoaceticus. J. Antimicrob Chemother 20:773-778.
16. Joly-Guillou, M. L., L. Vallée, E. Bergogne-Bèrezin, and A. Philippen. 1988. Distribution of β-lactamases and phenotype analysis in clinical strains of Acinetobacter calcoaceticus. J. Antimicrob. Chemother. 22:597-604.
17. Kuah, B. G., G. Kumarasinghe, J. Doran, and H. R. Chang. 1994. Antimicrobial susceptibilities of clinical isolates of Acinetobacter baumannii from Singapore. Antimicrob. Agents Chemother. 38:2502-2503.
18. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bactenophage T4 Nature (London) 227:680-685
19. Matagne, A., A.-M. Messelyn-Bauduin, B. Joris, T. Erpicum, B. Granier, and J.-M. Frère. 1990. The diversity of the catalytic properties of class A β-lactamases. Biochem J. 265:131-146.
20. Morohoshi, T., and T. Saito. 1977. β-Lactamase and β-lactam antibiotics resistance in Acinetobacter anuratum (syn: A. calcoaceticus). J. Antibiot 30: 969-973.
21. National Committee for Clinical Laboratory Standards. 1990. Reference methods for the determination of minimum inhibitory concentrations (MICs) of aerobic bacteria by broth macrodilution, broth microdilution. and agar dilution. Approved standard M7-A2. National Committee for Clinical Laboratory Standards. Villanova, Pa.
22. Obara, M., and T. Nakae. 1991. Mechanisms of resistance to β-lactam antibiotics in Acinetobacter calcoaceticus. J. Antimicrob. Chemother. 28: 791-800.
23. Paul, G., M. L. Joly-Gouillou, E. Bergogne-Bèrezin, P. Nèvot, and A. Philippon. 1989. Novel carbenicillin-hydrolyzing β-lactamase (CARB-5) from Acinetobacter calcoaceticus var. anitratus. FKMS Microbiol Lett. 59:45-50.
24. Sato, K., and T. Nakae. 1991. Outer membrane permeability of Acinetobacter calcoaceticus and its implications in antibiotic resistance. J Antimicrob. Chemother. 28:35-45.
25. Segel, I. H. 1976. Biochemical calculations, p. 236-241. John Wiley & Sons, Inc., New York.
26. Traub, W. H., and M. Spohr. 1989. Antimicrobial drug susceptibility of clinical isolates of Acinetobacter species (A. baumannii, A haemolyticus, genospecies 3, and genospecies 6). Antimicrob. Agents Chemother. 33:1617-1619.
27. Von Graevenilz, A. 1995. Acinetobacter, Alcaligenes, Moraxella, and other non fermentative gram-negative bacteria, p. 520-532 In P. R. Murray. E. J Baron, M. A Pfaller, F C. Tenover, and R H. Yolken (ed.), Manual of clinical microbiology, 6th ed. American Society for Microbiology, Washington, D.C.