Identification of an I-Ed-restricted T-cell epitope of Escherichia coli outer membrane protein F

Infection and Immunity

Volumn 72, Issue 7, 2004, Pages 3907-3913

  Williams, Kristina M ^a   Bigley III, Elmer C ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 2; OUTER MEMBRANE PROTEIN F; PHENYLALANINE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; THREONINE; TYROSINE; AMINO ACID; HLA ANTIGEN CLASS 2; I E ANTIGEN; I-E-ANTIGEN; PORIN;

AMINO ACID SUBSTITUTION; ANTIGEN PRESENTING CELL; ARTICLE; BACTERIUM IDENTIFICATION; CANCER CELL CULTURE; CYTOKINE RELEASE; ESCHERICHIA COLI; HYBRIDOMA; LYMPHOMA CELL; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MASTOCYTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SPLEEN CELL; ANIMAL; IMMUNOLOGY; MAJOR HISTOCOMPATIBILITY COMPLEX; METABOLISM; MOUSE; T LYMPHOCYTE;

AMINO ACIDS; ANIMALS; EPITOPES; ESCHERICHIA COLI; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYBRIDOMAS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; PORINS; T-LYMPHOCYTES;

EID: 3042538082     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.7.3907-3913.2004     Document Type: Article

References (70)

1. Alurkar, V., and R. Kamat. 1997. Immunomodulatory properties of porins of some members of the family Enterobacteriaceae. Infect. Immun. 65:2382-2388.
2. + T cells that are dependent on MHC class II-bound peptide-flanking residues. J. Immunol. 169:739-749.
3. Arockiasamy, A., and S. Krishnaswamy. 2000. Homology model of surface antigen OmpC from Salmonella typhi and its functional implications. J. Biomol. Struct. Dyn. 18:261-271.
4. Banos, D. M., S. Lopez, C. F. Arias, and F. R. Esquivel. 1997. Identification of a T-helper cell epitope on the rotavirus VP6 protein. J. Virol. 71:419-426.
5. Bavoil, P., H. Nikaido, and K. von Meyenburg. 1977. Pleiotropic transport mutants of Escherichia coli lack porin, a major outer membrane protein. Mol. Gen. Genet. 158:23-33.
6. Bernardini, M. L., M. G. Sanna, A. Fontaine, and P. J. Sansonetti. 1993. OmpC is involved in invasion of epithelial cells by Shigella flexneri. Infect. Immun. 61:3625-3635.
7. Bhayani, H., and Y. Paterson. 1989. Analysis of peptide binding patterns in different major histocompatibility complex/T cell receptor complexes using pigeon cytochrome c-specific T cell hybridomas: evidence that a single peptide binds major histocompatibility complex in different conformations. J. Exp. Med. 170:1609-1625.
8. Blanco, F., A. Isibasi, C. R. Gonzalez, V. Ortiz, J. Paniagua, C. Arreguin, and J. Kumate. 1993. Human cell mediated immunity to porins from Salmonella typhi. Scand. J. Infect. Dis. 25:73-80.
9. Brown, J. H., T. S. Jardetzky, J. C. Gorga, L. J. Stern, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1993. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364:33-39.
10. Chen, J. S., R. G. Lorenz, J. Goldberg, and P. M. Allen. 1991. Identification and characterization of a T cell-inducing epitope of bovine ribonuclease that can be restricted by multiple class II molecules. J. Immunol. 147:3672-3678.
11. Chen, R., C. Kramer, W. Schmidmayr, U. Chen-Schmeisser, and U. Henning. 1982. Primary structure of major outer-membrane protein I (ompF protein, porin) of Escherichia coli B/r. Biochem. J. 203:33-43.
12. Chianese-Bullock, K. A., H. I. Russell, C. Moller, W. Gerhard, J. J. Monaco, and L. C. Eisenlohr. 1998. Antigen processing of two H2-IEd-restricted epitopes is differentially influenced by the structural changes in a viral glycoprotein. J. Immunol. 161:1599-1607.
13. Chicz, R. M., R. G. Urban, J. C. Gorga, D. A. Vignali, W. S. Lane, and J. L. Strominger. 1993. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J. Exp. Med. 178:27-47.
14. Chicz, R. M., R. G. Urban, W. S. Lane, J. C. Gorga, L. J. Stern, D. A. Vignali, and J. L. Strominger. 1992. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size. Nature 358:764-768.
15. Cowan, S. W., T. Schirmer, G. Rummel, M. Steiert, R. Ghosh, R. A. Pauptit, J. N. Jansonius, and J. P. Rosenbusch. 1992. Crystal structures explain functional properties of two E. coli porins. Nature 358:727-733.
16. Dai, G., N. K. Steede, and S. J. Landry. 2001. Allocation of helper T-cell epitope immunodominance according to three-dimensional structure in the human immunodeficiency virus type I envelope glycoprotein gp120. J. Biol. Chem. 276:41913-41920.
17. Demotz, S., H. M. Grey, E. Appella, and A. Sette. 1989. Characterization of a naturally processed MHC class II-restricted T-cell determinant of hen egg lysozyme. Nature 342:682-684.
18. Doolan, D. L., S. Southwood, R. Chesnut, E. Appella, E. Gomez, A. Richards, Y. I. Higashimoto, A. Maewal, J. Sidney, R. A. Gramzinski, C. Mason, D. Koech, S. L. Hoffman, and A. Sette. 2000. HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles. J. Immunol. 165:1123-1137.
19. Fahrer, A. M., H. M. Geysen, D. O. White, D. C. Jackson, and L. E. Brown. 1995. Analysis of the requirements for class II-restricted T cell recognition of a single determinant reveals considerable diversity in the T cell response and degeneracy of peptide binding to I-ed. J. Immunol. 155:2849-2857.
20. k. J. Exp. Med. 195:1043-1052.
21. Fremont, D. H., W. A. Hendrickson, P. Marrack, and J. Kappler. 1996. Structures of an MHC class II molecule with covalently bound single peptides. Science 272:1001-1004.
22. Fremont, D. H., D. Monnaie, C. A. Nelson, W. A. Hendrickson, and E. R. Unanue. 1998. Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. Immunity 8:305-317.
23. Galdiero, F., C. de L'ero, G., N. Benedetto, M. Galdiero, and M. A. Tufano. 1993. Release of cytokines induced by Salmonella typhimurium porins. Infect. Immun. 61:155-161.
24. Galdiero, M., G. Cipollaro de L'ero, G. Donnarumma, A. Marcatili, and F. Galdiero. 1995. Interleukin-1 and interleukin-6 gene expression in human monocytes stimulated with Salmonella typhimurium porins. Immunology 86:612-619.
25. Godkin, A. J., K. J. Smith, A. Willis, M. V. Tejada-Simon, J. Zhang, T. Elliott, and A. V. Hill. 2001. Naturally processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide-MHC interactions. J. Immunol. 166:6720-6727.
26. Guery, J. C., A. Sette, E. Appella, and L. Adorini. 1995. Constitutive presentation of dominant epitopes from endogenous naturally processed self-β2-microglobulin to class II-restricted T cells leads to self-tolerance. J. Immunol. 154:545-554.
27. Harris, D. P., H. M. Vordermeier, A. Arya, C. Moreno, and J. Ivanyi. 1995. Permissive recognition of a mycobacterial T-cell epitope: localization of overlapping epitope core sequences recognized in association with multiple major histocompatibility complex class II I-A molecules. Immunology 84: 555-561.
28. Hernandez, H. J., and M. J. Stadecker. 1999. Elucidation and role of critical residues of immunodominant peptide associated with T cell-mediated parasitic disease. J. Immunol. 163:3877-3882.
29. Isibasi, A., V. Ortiz-Navarrete, J. Paniagua, R. Pelayo, C. R. Gonzalez, J. A. Garcia, and J. Kumate. 1992. Active protection of mice against Salmonella typhi by immunization with strain-specific porins. Vaccine 10:811-813.
30. Jensen, P. E., D. A. Weber, W. P. Thayer, L. E. Westerman, and C. T. Dao. 1999. Peptide exchange in MHC molecules. Immunol. Rev. 172:229-238.
31. Kappler, J. W., B. Skidmore, J. White, and P. Marrack. 1981. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas: lack of independent antigen and H-2 recognition. J. Exp. Med. 153:1198-1214.
32. Katoh, M., Y. Itoh, K. Ogasawara, K. Kajino, H. Nishihori, A. Takahashi, N. Matsuki, K. Iwabuchi, T. O. Yoshida, R. A. Good, and K. Onoe. 1996. A promiscuous T cell hybridoma restricted to various I-A molecules. Eur. J. Immunol. 26:976-980.
33. Kilgus, J., T. Jardetzky, J. C. Gorga, A. Trzeciak, D. Gillessen, and F. Sinigaglia. 1991. Analysis of the permissive association of a malaria T cell epitope with DR molecules. J. Immunol. 146:307-315.
34. Klebba, P. E., S. A. Benson, S. Bala, T. Abdullah, J. Reid, S. P. Singh, and H. Nikaido. 1990. Determinants of OmpF porin antigenicity and structure. J. Biol. Chem. 265:6800-6810.
35. Kurata, A., and J. A. Berzofsky. 1990. Analysis of peptide residues interacting with MHC molecule or T cell receptor: can a peptide bind in more than one way to the same MHC molecule? J. Immunol. 144:4526-4535.
36. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
37. Leighton, J., A. Sette, J. Sidney, E. Appella, C. Ehrhardt, S. Fuchs, and L. Adorini. 1991. Comparison of structural requirements for interaction of the same peptide with I-Ek and I-ed. molecules in the activation of MHC class II-restricted T cells. J. Immunol. 147:198-204.
38. Maillere, B., G. Mourier, M. Herve, and A. Menez. 1995. Fine chemical modifications at N- and C-termini enhance peptide presentation to T cells by increasing the lifespan of both free and MHC-complexed peptides. Mol. Immunol. 32:1377-1385.
39. McClelland, M., K. E. Sanderson, J. Spieth, S. W. Clifton, P. Latreille, L. Courtney, S. Porwollik, J. Ali, M. Dante, F. Du, S. Hou, D. Layman, S. Leonard, C. Nguyen, K. Scott, A. Holmes, N. Grewal, E. Mulvaney, E. Ryan, H. Sun, L. Florea, W. Miller, T. Stoneking, M. Nhan, R. Waterston, and R. K. Wilson. 2001. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature 413:852-856.
40. d class II histocompatibility molecules. Mol. Immunol. 34:145-155.
41. Nelson, C. A., N. J. Viner, and E. R. Unanue. 1996. Appreciating the complexity of MHC class II peptide binding: lysozyme peptide and I-Ak. Immunol. Rev. 151:81-105.
42. Nurminen, M. 1978. A mild procedure to isolate the 34K, 35K and 36K porins of the outer membrane of Salmonella typhimurium. FEMS Microbiol. Lett. 3:331-334.
43. O'Sullivan, D., T. Arrhenius, J. Sidney, M. F. Del Guercio, M. Albertson, M. Wall, C. Oseroff, S. Southwood, S. M. Colon, F. C. Gaeta, et al. 1991. On the interaction of promiscuous antigenic peptides with different DR alleles: identification of common structural motifs. J. Immunol. 147:2663-2669.
44. Panina-Bordignon, P., A. Tan, A. Termijtelen, S. Demotz, G. Corradin, and A. Lanzavecchia. 1989. Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur. J. Immunol. 19:2237-2242.
45. Parkhill, J., G. Dougan, K. D. James, N. R. Thomson, D. Pickard, J. Wain, C. Churcher, K. L. Mungall, S. D. Bentley, M. T. Holden, M. Sebaihia, S. Baker, D. Basham, K. Brooks, T. Chillingworth, P. Connerton, A. Cronin, P. Davis, R. M. Davies, L. Dowd, N. White, J. Farrar, T. Feltwell, N. Hamlin, A. Haque, T. T. Hien, S. Holroyd, K. Jagels, A. Krogh, T. S. Larsen, S. Leather, S. Moule, P. O'Gaora, C. Parry, M. Quail, K. Rutherford, M. Simmonds, J. Skelton, K. Stevens, S. Whitehead, and B. G. Barrell. 2001. Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature 413:848-852.
46. Reiser, J. B., C. Darnault, A. Guimezanes, C. Gregoire, T. Mosser, A. M. Schmitt-Verhulst, J. C. Fontecilla-Camps, B. Malissen, D. Housset, and G. Mazza. 2000. Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat. Immunol. 1:291-297.
47. Robadey, C., H. J. Wallny, and S. Demotz. 1996. Cell type-specific processing of the I-ed-restricted hen egg lysozyme determinant 107-116. Eur. J. Immunol. 26:1656-1659.
48. Romagnani, S. 2000. T-cell subsets (Th1 versus Th2). Ann. Allergy Asthma Immunol. 85:9-18.
49. Roman, E., D. P. Harris, S. Jurcevic, J. Ivanyi, and C. Moreno. 1995. H-2-associated effects of flanking residues on the recognition of a permissive mycobacterial T-cell epitope. Immunology 86:183-189.
50. Ruberti, G., K. S. Sellins, C. M. Hill, R. N. Germain, C. G. Fathman, and A. Livingstone. 1992. Presentation of antigen by mixed isotype class II molecules in normal H-2d mice. J. Exp. Med. 175:157-162.
51. Schild, H., U. Gruneberg, G. Pougialis, H. J. Wallny, W. Keilholz, S. Stevanovic, and H. G. Rammensee. 1995. Natural ligand motifs of H-2E mulecules ara allele specific and illustrate homology to HLA-DR molecules. Int. Immunol. 7:1957-1965.
52. Scott, C. A., P. A. Peterson, L. Teyton, and I. A. Wilson. 1998. Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity 8:319-329.
53. Sette, A., S. Buus, E. Appella, J. A. Smith, R. Chesnut, C. Miles, S. M. Colon, and H. M. Grey. 1989. Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis. Proc. Natl. Acad. Sci. USA 86:3296-3300.
54. Sette, A., J. Sidney, F. C. Gaeta, E. Appella, S. M. Colon, M. F. del Guercio, J. C. Guery, and L. Adorini. 1993. MHC class II molecules bind indiscriminately self and non-self peptide homologs: effect on the immunogenicity of non-self peptides. Int. Immunol. 5:631-638.
55. Sidney, J., M. F. del Guercio, S. Southwood, and A. Sette. 2002. The HLA molecules DQA1*0501/B1*0201 and DQA1*0301/B1*0302 share an extensive overlap in peptide binding specificity. J. Immunol. 169:5098-5108.
56. Simonet, V., M. Mallea, D. Fourel, J. M. Bolla, and J. M. Pages. 1996. Crucial domains are conserved in Enterobacteriaceae porins. FEMS Microbiol. Lett. 136:91-97.
57. Singh, S. P., S. Miller, Y. U. Williams, K. E. Rudd, and H. Nikaido. 1996. Immunochemical structure of the OmpD porin from Salmonella typhimurium. Microbiology 142(Pt. 11):3201-3210.
58. Singh, S. P., S. R. Singh, Y. U. Williams, L. Jones, and T. Abdullah. 1995. Antigenic determinants of the OmpC porin from Salmonella typhimurium. Infect. Immun. 63:4600-4605.
59. Singh, S. P., Y. Upshaw, T. Abdullah, S. R. Singh, and P. E. Klebba. 1992. Structural relatedness of enteric bacterial porins assessed with monoclonal antibodies to Salmonella typhimurium OmpD and OmpC. J. Bacteriol. 174: 1965-1973.
60. Southwood, S., J. Sidney, A. Kondo, M. F. del Guercio, E. Appella, S. Hoffman, R. T. Kubo, R. W. Chesnut, H. M. Grey, and A. Sette. 1998. Several common HLA-DR types share largely overlapping peptide binding repertoires. J. Immunol. 160:3363-3373.
61. Spencer, J. S., J. H. Freed, and R. T. Kubo. 1993. Expression and function of mixed isotype MHC class II molecules in normal mice. J. Immunol. 151: 6822-6832.
62. Stern, L. J., J. H. Brown, T. S. Jardetzky, J. C. Gorga, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1994. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368:215-221.
63. d-restricted determinants and T cell epitopes from the major bee venom allergen. Int. Immunol. 11:1313-1326.
64. Vignali, D. A., R. G. Urban, R. M. Chicz, and J. L. Strominger. 1993. Minute quantities of a single immunodominant foreign epitope are presented as large nested sets by major histocompatibility complex class II molecules. Eur. J. Immunol. 23:1602-1607.
65. Viner, N. J., C. A. Nelson, and E. R. Unanue. 1995. Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity. Proc. Natl. Acad. Sci. USA 92:2214-2218.
66. Vordermeier, H. M., D. P. Harris, C. Moreno, and J. Ivanyi. 1994. Promiscuous T cell recognition of an H-2 IA-presented mycobacterial epitope. Eur. J. Immunol. 24:2061-2067.
67. Wei, J., M. B. Goldberg, V. Burland, M. M. Venkatesan, W. Deng, G. Fournier, G. F. Mayhew, G. Plunkett III, D. J. Rose, A. Darling, B. Mau, N. T. Perna, S. M. Payne, L. J. Runyen-Janecky, S. Zhou, D. C. Schwartz, and F. R. Blattner. 2003. Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect. Immun. 71: 2775-2786.
68. Wiertz, E., J. van Gaans-van den Brink, P. Hoogerhout, and J. Poolman. 1993. Microheterogeneity in the recognition of a HLA-DR2- restricted T cell epitope from a meningococcal outer membrane protein. Eur. J. Immunol. 23:232-239.
69. Williams, K. M., E. C. Bigley III, and R. B. Raybourne. 2000. Identification of murine B-cell and T-cell epitopes of Escherichia coli outer membrane protein F with synthetic polypeptides. Infect. Immun. 68:2535-2545.
70. Yassai, M., A. Afsari, J. Garlie, and J. Gorski. 2002. C-terminal anchoring of a peptide to class II MHC via the P10 residue is compatible with a peptide bulge. J. Immunol. 168:1281-1285.