Molecular characterization of a Brugia malayi transglutaminase

Parasitology Research

Volumn 93, Issue 2, 2004, Pages 145-150

  Devarajan, Eswaran ^a,d   Mishra, Pankaj Kumar ^b   Thirugnanam, Shiva ^b   Mehta, Kapil ^a   Chandrashekar, Ramaswamy ^c   Perumal, Kaliraj ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b ANNA UNIVERSITY   (India)

^c IDEXX LABORATORIES   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; COMPLEMENTARY DNA; EDETIC ACID; MESSENGER RNA; PROTEIN DISULFIDE ISOMERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN P60;

AMINO ACID SEQUENCE; ANTIBODY DEPENDENT ENHANCEMENT; ARTICLE; BRUGIA MALAYI; CONTROLLED STUDY; DNA DETERMINATION; ENDEMIC DISEASE; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME INHIBITION; FILARIASIS; GENE AMPLIFICATION; MOLECULAR CLONING; MOLECULAR RECOGNITION; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, HELMINTH; BRUGIA MALAYI; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FILARIASIS; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TRANSGLUTAMINASES;

BRUGIA; BRUGIA MALAYI;

EID: 3042533537     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-004-1121-9     Document Type: Article

References (29)

1. Adini A, Krugliak M, Ginsburg H, Li L, Lavie L, Warburg O (2001) Transglutaminase in Plasmodium parasites: activity and putative role in oocysts and blood stages. Mol Biochem Parasitol 117:161-168
2. Blasko B, Madi A, Fesus L (2003) Thioredoxin motif of Caenorhabdilis elegans PDI-3 provides Cys and His catalytic residues for transglutaminase activity. Biochem Biophys Res Commun 303:1142-1147
3. Chandrashekar R (2001) Parasitic nematode transgluaminase, nucleic acid molecules, and uses thereof. US Patent 6,248,872
4. Chandrashekar R (2002). Novel parasite (nematode) transglutaminase- potential drug target. Indian J Exp Biol 40:753-754
5. Chandrasekar R, Mehta K (2000) Transglutaminase-catalysed reactions in the growth and development of parasitic nematodes. Parasitol Today 16:11-17
6. Chandrashekar R, Tsuji N, Morales T, Ozols V, Mehta K (1998) An ERp60-like protein from the filarial parasite D. immitis has both transglutaminase and protein disulfide isomerase activity. Proc Natl Acad Sci U S A 95:531-536
7. Chandrasekar R, Devarajan E, Mehta K (2002) D. immitis: further characterization of the transglutaminase enzyme and its role in larval molting. Parasitol Res 88:185-191
8. Eschenlauer SC, Page AP (2003). The Caenorhabditis elegans ERp60 homolog protein disulfide isomerase-3 has disulfide isomerase and transglutaminase-like cross-linking activity and is involved in the maintenance of body morphology. J Biol Chem 278:4227-4237
9. Elson LH, Guderian, RH, Araujo E, Bradley JE, Days A, Nutman TB (1994) Immunity to onchocerciasis: identification of a putatively immune population in a hyperendemic area of Ecuador. J Infect Dis 169:588
10. Gregory WF, Atmadja AK, Allien JE, Maizels R (2000) The abundant transcript-1 and -2 genes of B. malayi encode stage specific candidate vaccines antigens for filariasis. Infect Immun 68:4147-4179
11. Hasegawa G, Suwa M, Ichikawa Y, Ohtsuka T, Kumagai S, Kikuchi M, Sato Y, Saito Y (2003) A novel function of tissue-type transglutaminase: protein disulphide isomerase. Biochem J 373:793-803
12. Irvine M, Johnson EH, Lustigman S (1997) Identification of larval-stage-specific antigens of Onchocerca volvulus uniquely recognized by putative immune sera from humans and vaccination sera from animal models. Ann Trop Med Parasitol 91:67-77
13. Kemmink J, Darby NJ, Dijkstra K, Nilges M, Creighton TE (1997) The folding catalyst protein disulfide isomerase is constructed of active and inactive thioredoxin modules. Curr Biol 7:239-45
14. Keiser PB, Nutman TB (2002) Update on lymphatic filarial infections. Curr Infect Dis Rep 4:65-69
15. Knodler LA, Noiva R, Mehta K, McCaffery JM, Aley SB, Svard SG, Nystul TG, Reiner DS, Silberman JD, Gillin FD (1999) Novel protein-disulfide isomerases from the early-diverging protest Giardia lamblia. J Biol Chem 274:29805-29811
16. Lalitha P, Eswaran D, Gnansekar M, Rao KVN, Narayanan RB, Scott A, Nutman T, Kaliraj P (2002) Development of antigen detection ELISA for the diagnosis of Brugian and Bancroftian filariasis using antibodies to recombinant filarial antigens Bm-SXP-1 and Wb-SXP-1 Microbiol Immunol 46:327-332
17. Lizotte WM, Tawe W, Guiliano DB, Lu W, Liu J, William SA, Lustigman S (2002) Identification of potential vaccine and drug target candidates by expressed sequence tag analysis and immunoscreening of Onchocerca volvulus larval cDNA libraries. Infect Immun 68:3491-3501
18. Lustigman S, Brotman B, Huima T, Castelhano AL, Singh RN, Mehta K, Prince AM (1995) Transglutaminase-catalyzed reaction is important for molting of Onchocerca volvulus third-stage larvae. Antimicrob Agents Chemother 39:1913-1919
19. McCarthy JS, Nutman TB (1996) Perspective: prospects for development of vaccines against human helminth infections. J Infect Dis 174:1384-1390
20. Mehta K, Rao, UR, Vickery AC, Birckbichler PJ (1990) Significance of transglutaminase catalysed reactions in growth and development of filarial parasite, B. malayi. Biochem Biophy Res Commun 173:1051-1057
21. Michael E, Bundy DA, Grenfell BT (1996) Reassessing the global prevalence and distribution of lymphatic filariasis. Parasitology 112:409-428
22. Murray J, Gregory WF, Gomez-Escobar N, Atmadja AK, Maizels RM (2001) Expression and immune recognition of B. malayi VAL-1, a homologue of vespid venom allergens and Ancylostoma secreted proteins. Mol Biochem Parasitol 118:89-96
23. Natsuka S, Takubo R, Seki R, Ikura K (2001) Molecular characterization and expression of Caenorhabditis elegans ERp57-homologue with transglutaminase activity. J Biochem 130:731-735
24. Nutman TB, Steel C, Ward DJ, Zea-Flores G, Ottesen EA (1991) Immunity to onchocerciasis: recognition of larval antigens by human putative immune to Onchocerca volvulus infection. J Infect Dis 163:1128-1133
25. Rao KV, Eswaran M, Ravi V, Gnanasekhar B, Narayanan RB, Kaliraj P, Jayaraman K, Marson A, Raghavan N, Scott AL (2000) The Wuchereria bancrofti orthologue of Brugia malayi SXP1 and the diagnosis of bancroftian filariasis. Mol Biochem Parasitol 107:71-80
26. Rao UR, Mehta K, Subrahmanyam D, Vickery AC (1991) B. malayi and Acanthocheilonema viteae: antifilarial activity of transglutaminase inhibitors in vitro. Antimicrob Agents Chemother 35:2219-2224
27. Sharma S, Bhattacharyya MK (1997) Novel putative protective antigens of Plasmodium falciparum. Indian J Med Res 106:63-69
28. Slaughter TF, Achyuthan KE, Lai TS, Greenberg CS (1992) A microtiter plate transglutaminase assay utilizing 5-(biotinamido) pentylamine as substrate. Anal. Biochem 205:166-171
29. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673-4680