Photoreceptor death, trophic factor expression, retinal oxygen status, and photoreceptor function in the P23H rat

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 6, 2004, Pages 2013-2019

  Yu, Dao Yi ^a   Cringle, Stephen ^a   Valter, Krisztina ^b,c   Walsh, Natalie ^b   Lee, Donald ^b   Stone, Jonathan ^b,c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; DNA FRAGMENT; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GLIAL FIBRILLARY ACIDIC PROTEIN; OXYGEN; RHODOPSIN; NERVE GROWTH FACTOR;

A WAVE; ADOLESCENT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL DEATH; CONTROLLED STUDY; DARK ADAPTATION; ELECTRORETINOGRAPHY; HETEROZYGOTE; HYPEROXIA; IMMUNOHISTOCHEMISTRY; NEWBORN; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; OXYGEN TENSION; OXYGEN TISSUE LEVEL; PHOTORECEPTOR; PRIORITY JOURNAL; RAT; RETINA DEGENERATION; RETINITIS PIGMENTOSA; ANIMAL; DISEASE MODEL; GENETICS; ION SELECTIVE ELECTRODE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; RAT STRAIN; SPRAGUE DAWLEY RAT; TIME; UPREGULATION;

ANIMALS; CELL DEATH; DARK ADAPTATION; DISEASE MODELS, ANIMAL; DNA FRAGMENTATION; ELECTRORETINOGRAPHY; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; ION-SELECTIVE ELECTRODES; NERVE GROWTH FACTORS; OXYGEN CONSUMPTION; PHOTIC STIMULATION; PHOTORECEPTORS, VERTEBRATE; RATS; RATS, MUTANT STRAINS; RATS, SPRAGUE-DAWLEY; RETINITIS PIGMENTOSA; TIME FACTORS; UP-REGULATION;

EID: 3042526482     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0845     Document Type: Article

References (31)

1. Valter K, Maslim J, Bowers F, Stone J. Photoreceptor dystrophy in the RCS rat: roles of oxygen, debris and bFGF. Invest Ophthalmol Vis Sci. 1998;39:2427-2442.
2. Stone J, Maslim J, Valter-Kocsi K, et al. Mechanisms of photoreceptor death and survival in mammalian retina. Prog Retin Eye Res. 1999;18:689-735.
3. Walsh N, Valter K, Stone J. Cellular and subcellular patterns of expression of bFGF and CNTF in the normal and light stressed adult rat retina. Exp Eye Res. 2001;72:495-501.
4. Yu DY, Cringle SJ, Su EN, Yu PK. Intraretinal oxygen levels before and after photoreceptor loss in the RCS Rat. Invest Ophthalmol Vis Sci. 2000;41:3999-4006.
5. Yu DY, Cringle SJ. Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease. Prog Retin Eye Res. 2001;20:175-208.
6. Machida S, Kondo M, Jamison JA, et al. P23H rhodopsin transgenic rat: correlation of retinal function with histopathology. Invest Ophthalmol Vis Sci. 2000;41:3200-3209.
7. Nir I, Harrison JM, Liu C, Wen R. Extended photoreceptor viability by light stress in the RCS rats but not in the opsin P23H mutant rats. Invest Ophthalmol Vis Sci. 2001;42:842-849.
8. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 1992;119:493-501.
9. Maslim J, Valter K, Egensperger R, Hollander H, Stone J. Tissue oxygen during a critical developmental period controls the death and survival of photoreceptors. Invest Ophthalmol Vis Sci. 1997; 38:1667-1677.
10. Mervin K, Valter K, Maslim J, Lewis G, Fisher S, Stone J. Limiting photoreceptor death and deconstruction during experimental retinal detachment: the value of oxygen supplementation. Am J Ophthalmol. 1999;128:155-164.
11. Valter K, van Driel D, Bisti S, Stone J. FGFR1 expression and FGFR1-FGF2 colocalisation in rat retina: sites of FGF-2 action on rat photoreceptors. Growth Factors. 2002;20:177-188.
12. Yu D, Cringle S, Alder V, Su E. Intraretinal oxygen distribution in rats as a function of systemic blood pressure. Am J Physiol. 1994;267:H2498-H2507.
13. Yu DY, Cringle SJ, Constable IJ. Robotic ocular ultramicrosurgery. Aust NZ J Ophthalmol. 1998;26(suppl 1):S6-S8.
14. Lyubarsky AL, Pugh ENJ. Recovery phase of the murine rod photoresponse reconstructed from electroretinographic recordings. J Neurosci. 1996;16:563-571.
15. Pugh E, Falsini B, Lyubarsky A. The origin of the major rod-and cone-driven components of the rodent electroretinogram and the effect of age and light-rearing history on the magnitude of these components. Photostasis and Related Phenomena. New York: Plenum Press; 1998:93-128.
16. Yu DY, Alder VA, Cringle SJ, Su EN, Burns M. Intraretinal oxygen distribution in urethane-induced retinopathy in rats. Am J Physiol. 1998;274:H2009-H2017.
17. Desire L, Courtois Y, Jeanny JC. Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal bcl-x(L) and bcl-2 expression through a fibroblast growth factor receptor 1- and ERK-dependent pathway. J Neurochem. 2000;75:151-163.
18. Braun R, Linsenmeier R, Goldstick T. Oxygen consumption in the inner and outer retina of the cat. Invest Ophthalmol Vis Sci. 1995;36:542-554.
19. Chan-Ling T, Stone J. Retinopathy of prematurity: origins in the architecture of the retina. Prog Retin Res. 1993;12:155-176.
20. Stone J, Maslim J. Mechanisms of retinal angiogenesis. Prog Retin Eye Res. 1997;16:157-181.
21. Alon T, Hemo I, Itin A, Pe'er J, Stone J, Keshet E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med. 1995;1:1024-1028.
22. Heckenlively J. Retinitis Pigmentosa. Philadelphia: JB Lippincott; 1988.
23. Penn JS, Li S, Naash MI. Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2000;41:4007-4013.
24. Sato M, Ohguro H, Ohguro I, et al. Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis. Biochem Biophys Res Commun. 2003;306:826-831.
25. Ryter S, Choi A. Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress. Antioxid Redox Signal. 2002;4:625-632.
26. Anderson B, Saltzman H. Retinal oxygen utilization measured by hyperbaric blackout. Arch Ophthalmol. 1964;72:792-795.
27. + transport. J Neurosci. 1992;12:840-853.
28. Coyle JT, Puttfarcken P. Oxidative stress, glutamate and neurodegenerative disorders. Science. 1993;262:689-695.
29. Anderson B. Ocular effects of changes in oxygen and carbon dioxide tension. Trans Ophthalmol Soc. 1968;66:423-474.
30. Noell WK. Visual cell effects of high oxygen pressures. Am Physiol Soc Fed Proc. 1955;14:107-108.
31. Yamada H, Yamada E, Ando A, et al. Fibroblast growth factor-2 decreases hyperoxia-induced photoreceptor cell death in mice. Am J Pathol. 2001;159:1113-1120.