Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder

Biological Psychiatry

Volumn 56, Issue 2, 2004, Pages 95-100

  Fujita, Masahiro ^a,c   Southwick, Steven M ^a   Denucci, Christopher C ^c   Zoghbi, Sami S ^b,c   Dillon, Martha S ^a   Baldwin, Ronald M ^a   Bozkurt, Ali ^a   Kugaya, Akira ^a   Verhoeff, N Paul L G ^a   Seibyl, John P ^d   Innis, Robert B ^a,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^d Inst for Neurodeg Disorders   (United States)

Author keywords

childhood trauma; combat; iomazenil; reproducibility; Single photon emission computed tomography; statistical parametric mapping

Indexed keywords

BENZODIAZEPINE RECEPTOR; IODINE 123; IOMAZENIL;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; INJURY; MALE; PARAMETER; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; SCORING SYSTEM; SOLDIER; STATISTICAL SIGNIFICANCE; STATISTICS; UNITED KINGDOM;

ADULT; COMBAT DISORDERS; FEMALE; FLUMAZENIL; HUMANS; IODINE RADIOISOTOPES; LIFE CHANGE EVENTS; MALE; MATCHED-PAIR ANALYSIS; PREFRONTAL CORTEX; RECEPTORS, GABA-A; REFERENCE VALUES; STRESS DISORDERS, POST-TRAUMATIC; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; UNITED STATES; VETERANS;

EID: 3042522758     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2004.03.010     Document Type: Article

References (41)

1. Abi-Dargham A., Laruelle M., Krystal J., D'Souza C., Zoghbi S., Baldwin R.M., et al. No evidence of altered in vivo benzodiazepine receptor binding in schizophrenia. Neuropsychopharmacology. 20:1999;650-661
2. 123I]iomazenil Kinetic and equilibrium paradigms. J Nucl Med. 35:1994;228-238
3. Bernstein E.M., Putnam F.W. Development, reliability, and validity of a dissociation scale. J Nerv Ment Dis. 174:1986;727-735
4. Blake D.D., Weathers F.W., Nagy L.M., Kaloupek D.G., Klauminzer G., Charney D.S., et al. A clinician rating scale for assessing current and lifetime PTSD The CAPS-1. Behav Ther. 13:1990;187-188
5. Bonne O., Brandes D., Gilboa A., Gomori J.M., Shenton M.E., Pitman R.K., et al. Longitudinal MRI study of hippocampal volume in trauma survivors with PTSD. Am J Psychiatry. 158:2001;1248-1251
6. Braun P., Greenberg D., Dasberg H., Lerer B. Core symptoms of posttraumatic stress disorder unimproved by alprazolam treatment. J Clin Psychiatry. 51:1990;236-238
7. Bremner C., Scott T.M., Delaney R.C., Southwick S.M., Mason J.W., Johnson D.R., et al. Deficits in short-term memory in post-traumatic stress disorder. Am J Psychiatry. 150:1993;1015-1019
8. Bremner J.D. Neuroimaging studies in post-traumatic stress disorder. Curr Psychiatry Rep. 4:2002;254-263
9. Bremner J.D., Innis R.B., Southwick S.M., Staib L., Zoghbi S., Charney D.S. Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder. Am J Psychiatry. 157:2000;1120-1126
10. Bremner J.D., Krystal J.H., Putnam F.W., Southwick S.M., Marmar C., Charney D.S., et al. Measurement of dissociative states with the Clinician-Administered Dissociative States Scale (CADSS). J Trauma Stress. 11:1998;125-136
11. Bremner J.D., Vermetten E., Mazure C.M. Development and preliminary psychometric properties of an instrument for the measurement of childhood trauma The Early Trauma Inventory. Depress Anxiety. 12:2000;1-12
12. Collins D.L., Neelin P., Peters T.M., Evans A.C. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr. 18:1994;192-205
13. De Bellis M.D., Keshavan M.S., Frustaci K., Shifflett H., Iyengar S., Beers S.R., et al. Superior temporal gyrus volumes in maltreated children and adolescents with PTSD. Biol Psychiatry. 51:2002;544-552
14. De Bellis M.D., Keshavan M.S., Shifflett H., Iyengar S., Dahl R.E., Axelson D.A., et al. Superior temporal gyrus volumes in pediatric generalized anxiety disorder. Biol Psychiatry. 51:2002;553-562
15. 3H]Ro 5-4864 binding to "peripheral-type" benzodiazepine receptors in the rat. Pharmacol Biochem Behav. 24:1986;1673-1677
16. Fujita M., Woods S.W., Verhoeff N.P.L.G., Abi-Dargham A., Baldwin R.M., Zoghbi S.S., et al. Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans. Eur J Pharmacol. 368:1999;161-172
17. Green B.L., Lindy J.D., Grace M.C., Gleser G.C., Leonard A.C., Korol M., et al. Buffalo Creek survivors in the second decade Stability of stress symptoms. Am J Orthopsychiatry. 60:1990;43-54
18. Grillon C., Morgan C.A. III, Davis M., Southwick S.M. Effects of experimental context and explicit threat cues on acoustic startle in Vietnam veterans with posttraumatic stress disorder. Biol Psychiatry. 44:1998;1027-1036
19. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 32:1959;50-55
20. Herrmann N., Eryavec G. Delayed onset post-traumatic stress disorder in World War II veterans. Can J Psychiatry. 39:1994;439-441
21. Hull A.M. Neuroimaging findings in post-traumatic stress disorder. Systematic review. Br J Psychiatry. 181:2002;102-110
22. Innis R.B., Al-Tikriti M.S., Zoghbi S.S., Baldwin R.M., Sybirska E.H., Laruelle M.A., et al. SPECT imaging of the benzodiazepine receptor Feasibility of in vivo potency measurements from stepwise displacements curves. J Nucl Med. 32:1991;1754-1761
23. Keane T.M., Caddell J.M., Taylor K.L. Mississippi Scale for Combat-Related Posttraumatic Stress Disorder Three studies in reliability and validity. J Consult Clin Psychol. 56:1988;85-90
24. 123I]iomazenil SPECT. Biol Psychiatry. 54:2003;792-799
25. Lippa A.S., Klepner C.A., Yunger L., Sano M.C., Smith W.V., Beer B. Relationship between benzodiazepine receptors and experimental anxiety in rats. Pharmacol Biochem Behav. 9:1978;853-856
26. Lund M., Foy D., Sipprelle C., Strachan A. The Combat Exposure Scale A systematic assessment of trauma in the Vietnam War. J Clin Psychol. 40:1984;1323-1328
27. Medina J.H., Novas M.L., Wolfman C.N., Levi de Stein M., De Robertis E. Benzodiazepine receptors in rat cerebral cortex and hippocampus undergo rapid and reversible changes after acute stress. Neuroscience. 9:1983;331-335
28. Müller-Gätner H.W., Links J.M., Prince J.L., Bryan R.N., McVeigh E., Leal J.P., et al. Measurement of radiotracer concentration in brain gray matter using positron emission tomography MRI-based correction for partial volume effects. J Cereb Blood Flow Metab. 12:1992;571-583
29. Oldfield R.C. The assessment and analysis of handedness The Edinburgh inventory. Neuropsychologia. 9:1971;97-113
30. Pham D.L., Prince J.L. Adaptive fuzzy segmentation of magnetic resonance images. IEEE Trans Med Imaging. 18:1999;737-752
31. Port C.L., Engdahl B., Frazier P. A longitudinal and retrospective study of PTSD among older prisoners of war. Am J Psychiatry. 158:2001;1474-1479
32. Russell E. A multiple scoring method for the assessment of complex memory functions. J Consult Clin Psychol. 43:1975;800-809
33. A receptor subtypes. Pharmaco Rev. 47:1995;181-234
34. Smith S.M. Fast robust automated brain extraction. Hum Brain Mapp. 17:2002;143-155
35. Tzourio-Mazoyer N., Landeau B., Papathanassiou D., Crivello F., Etard O., Delcroix N., et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 15:2002;273-289
36. Van Dyke C., Zilberg N.J., McKinnon J.A. Posttraumatic stress disorder A thirty-year delay in a World War II veteran. Am J Psychiatry. 142:1985;1070-1073
37. 123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia. Psychiatry Res. 91:1999;163-173
38. Weizman R., Weizman A., Kook K.A., Vocci F., Deutsch S.I., Paul S.M. Repeated swim stress alters brain benzodiazepine receptors measured in vivo. J Pharmacol Exp Ther. 249:1989;701-707
39. Widom C.S. Posttraumatic stress disorder in abused and neglected children grown up. Am J Psychiatry. 156:1999;1223-1229
40. Zar J.H. Biostatistical Analysis. 1996;Prentice-Hall, Upper Saddle River, NJ
41. 123I]iomazenil in human and nonhuman primates. Int J Rad Appl Instrum B. 19:1992;881-888