-
1
-
-
0036493584
-
Effects of anagrelide on in vivo megakaryocyte proliferation and maturation in essential thrombocythemia
-
A. Tomer Effects of anagrelide on in vivo megakaryocyte proliferation and maturation in essential thrombocythemia Blood 99 2002 1602 1609
-
(2002)
Blood
, vol.99
, pp. 1602-1609
-
-
Tomer, A.1
-
3
-
-
0026704780
-
A phase II pilot trial of high-dose hydroxyurea in chronic myelogenous leukemia
-
J.E. Kolitz, S.J. Kempin, and A. Schluger A phase II pilot trial of high-dose hydroxyurea in chronic myelogenous leukemia Semin Oncol 19 1992 27 33
-
(1992)
Semin Oncol
, vol.19
, pp. 27-33
-
-
Kolitz, J.E.1
Kempin, S.J.2
Schluger, A.3
-
4
-
-
0037483282
-
Anagrelide, a therapy for thrombocythemic states: Experience in 577 patients. Anagrelide Study Group
-
Anagrelide Study Group Anagrelide, a therapy for thrombocythemic states: experience in 577 patients. Anagrelide Study Group Am J Med 92 1992 69 76
-
(1992)
Am J Med
, vol.92
, pp. 69-76
-
-
Study Group, A.1
-
5
-
-
0023946455
-
Anagrelide: A new drug for treating thrombocytosis
-
M.N. Silverstein, R.M. Petitt, L.A. Solberg Jr., J.S. Fleming, R.C. Knight, and L.P. Schacter Anagrelide: a new drug for treating thrombocytosis N Engl J Med 318 1998 1292 1294
-
(1998)
N Engl J Med
, vol.318
, pp. 1292-1294
-
-
Silverstein, M.N.1
Petitt, R.M.2
Solberg Jr., L.A.3
Fleming, J.S.4
Knight, R.C.5
Schacter, L.P.6
-
6
-
-
0026576978
-
Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders
-
C.L. Balduini, G. Bertolino, P. Noris, and E. Ascari Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders Haematologica 77 1992 40 43
-
(1992)
Haematologica
, vol.77
, pp. 40-43
-
-
Balduini, C.L.1
Bertolino, G.2
Noris, P.3
Ascari, E.4
-
7
-
-
0026639799
-
Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans
-
E.M. Mazur, A.G. Rosmarin, P.A. Sohl, J.L. Newton, and A. Narendran Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans Blood 79 1992 1931 1937
-
(1992)
Blood
, vol.79
, pp. 1931-1937
-
-
Mazur, E.M.1
Rosmarin, A.G.2
Sohl, P.A.3
Newton, J.L.4
Narendran, A.5
-
8
-
-
0034182328
-
[Cloning of a full length cDNA of human thrombopoietin receptor c-Mpl and construction of engineered cells that stably express c-mpl]
-
X.Y. Zhao, J.L. Cai, W.L. Dai, W.G. Zhou, C.B. Li, and S.Y. Zhao [Cloning of a full length cDNA of human thrombopoietin receptor c-Mpl and construction of engineered cells that stably express c-mpl] Sheng Wu Gong Cheng Xue Bao 16 2000 320 323
-
(2000)
Sheng Wu Gong Cheng Xue Bao
, vol.16
, pp. 320-323
-
-
Zhao, X.Y.1
Cai, J.L.2
Dai, W.L.3
Zhou, W.G.4
Li, C.B.5
Zhao, S.Y.6
-
9
-
-
0031317721
-
Cloning and sequencing of human thrombopoietin cDNA
-
Y. Fan, T. Gao, Y. Ye, and B. Tien Cloning and sequencing of human thrombopoietin cDNA Chin J Biotechnol 13 1997 219 223
-
(1997)
Chin J Biotechnol
, vol.13
, pp. 219-223
-
-
Fan, Y.1
Gao, T.2
Ye, Y.3
Tien, B.4
-
10
-
-
0028199208
-
Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo
-
S. Lok, K. Kaushansky, and R.D. Holly Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo Nature 369 1994 565 568
-
(1994)
Nature
, vol.369
, pp. 565-568
-
-
Lok, S.1
Kaushansky, K.2
Holly, R.D.3
-
11
-
-
0029121283
-
Modulation of megakaryocytopoiesis by thrombopoietin: The c-Mpl ligand
-
N. Banu, J.F. Wang, B. Deng, J.E. Groopman, and H. Avraham Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand Blood 86 1995 1331 1338
-
(1995)
Blood
, vol.86
, pp. 1331-1338
-
-
Banu, N.1
Wang, J.F.2
Deng, B.3
Groopman, J.E.4
Avraham, H.5
-
12
-
-
0028985594
-
Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development
-
K. Kaushansky, V.C. Broudy, and N. Lin Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development Proc Natl Acad Sci U S A 92 1995 3234 3238
-
(1995)
Proc Natl Acad Sci U S a
, vol.92
, pp. 3234-3238
-
-
Kaushansky, K.1
Broudy, V.C.2
Lin, N.3
-
13
-
-
0037251065
-
Etiology of the myeloproliferative disorders: The role of thrombopoietin
-
K. Kaushansky Etiology of the myeloproliferative disorders: the role of thrombopoietin Semin Hematol 40 2003 6 9
-
(2003)
Semin Hematol
, vol.40
, pp. 6-9
-
-
Kaushansky, K.1
-
14
-
-
0032227150
-
Myelofibrosis: Experimental models and human studies
-
A.L. Taskin, K. Cohen-Solal, and J.P. Le Couedic Myelofibrosis: experimental models and human studies Stem Cells 16 suppl 1998 155 164
-
(1998)
Stem Cells
, vol.16
, Issue.SUPPL.
, pp. 155-164
-
-
Taskin, A.L.1
Cohen-Solal, K.2
Le Couedic, J.P.3
-
15
-
-
0031795073
-
High levels of thrombopoietin in sera of patients with essential thrombocythemia: Cause or consequence of abnormal platelet production?
-
M. Griesshammer, A. Hornkohl, and J.L. Nichol High levels of thrombopoietin in sera of patients with essential thrombocythemia: cause or consequence of abnormal platelet production? Ann Hematol 77 1998 211 215
-
(1998)
Ann Hematol
, vol.77
, pp. 211-215
-
-
Griesshammer, M.1
Hornkohl, A.2
Nichol, J.L.3
-
16
-
-
0034490533
-
The platelet thrombopoietin receptor number and function are markedly decreased in patients with essential thrombocythaemia
-
J. Li, Y. Xia, and D.J. Kuter The platelet thrombopoietin receptor number and function are markedly decreased in patients with essential thrombocythaemia Br J Haematol 111 2000 943 953
-
(2000)
Br J Haematol
, vol.111
, pp. 943-953
-
-
Li, J.1
Xia, Y.2
Kuter, D.J.3
-
17
-
-
2642609475
-
Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera
-
A.R. Moliterno, W.D. Hankins, and J.L. Spivak Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera N Engl J Med 338 1998 572 580
-
(1998)
N Engl J Med
, vol.338
, pp. 572-580
-
-
Moliterno, A.R.1
Hankins, W.D.2
Spivak, J.L.3
-
18
-
-
0032227241
-
A novel thrombopoietin signaling defect in polycythemia vera platelets
-
A.R. Moliterno, K.E. Siebel, A.Y. Sun, W.D. Hankins, and J.L. Spivak A novel thrombopoietin signaling defect in polycythemia vera platelets Stem Cells 16 suppl 2 1998 185 192
-
(1998)
Stem Cells
, vol.16
, Issue.2 SUPPL.
, pp. 185-192
-
-
Moliterno, A.R.1
Siebel, K.E.2
Sun, A.Y.3
Hankins, W.D.4
Spivak, J.L.5
-
19
-
-
0028910991
-
The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl
-
J.G. Drachman, J.D. Griffin, and K. Kaushansky The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl J Biol Chem 270 1995 4979 4982
-
(1995)
J Biol Chem
, vol.270
, pp. 4979-4982
-
-
Drachman, J.G.1
Griffin, J.D.2
Kaushansky, K.3
-
20
-
-
0022274007
-
Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo
-
R. Palacios, and M. Steinmetz Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo Cell 41 1985 727 734
-
(1985)
Cell
, vol.41
, pp. 727-734
-
-
Palacios, R.1
Steinmetz, M.2
-
21
-
-
0025636017
-
M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3
-
G.C. Avanzi, M.F. Brizzi, and J. Giannotti M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3 J Cell Physiol 145 1990 458 464
-
(1990)
J Cell Physiol
, vol.145
, pp. 458-464
-
-
Avanzi, G.C.1
Brizzi, M.F.2
Giannotti, J.3
-
22
-
-
0025805472
-
Selection of normal human hematopoietic stem cells for bone marrow transplantation using immunomagnetic microspheres and CD34 antibody
-
L.C. Strauss, T.M. Trischmann, S.D. Rowley, J.M. Wiley, and C.I. Civin Selection of normal human hematopoietic stem cells for bone marrow transplantation using immunomagnetic microspheres and CD34 antibody Am J Pediatr Hematol Oncol 13 1991 217 221
-
(1991)
Am J Pediatr Hematol Oncol
, vol.13
, pp. 217-221
-
-
Strauss, L.C.1
Trischmann, T.M.2
Rowley, S.D.3
Wiley, J.M.4
Civin, C.I.5
-
23
-
-
0025048308
-
Cytokine-dependent long-term culture of highly enriched precursors of hematopoietic progenitor cells from human bone marrow
-
J. Brandt, E.F. Srour, K. van Besien, R.A. Briddell, and R. Hoffman Cytokine-dependent long-term culture of highly enriched precursors of hematopoietic progenitor cells from human bone marrow J Clin Invest 86 1990 932 941
-
(1990)
J Clin Invest
, vol.86
, pp. 932-941
-
-
Brandt, J.1
Srour, E.F.2
Van Besien, K.3
Briddell, R.A.4
Hoffman, R.5
-
24
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 1983 55 63
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
25
-
-
0035951790
-
Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes
-
Y. Miyakawa, P. Rojnuckarin, T. Habib, and K. Kaushansky Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes J Biol Chem 276 2001 2494 2502
-
(2001)
J Biol Chem
, vol.276
, pp. 2494-2502
-
-
Miyakawa, Y.1
Rojnuckarin, P.2
Habib, T.3
Kaushansky, K.4
-
26
-
-
0033566712
-
Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: Role in endomitosis
-
P. Rojnuckarin, J.G. Drachman, and K. Kaushansky Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis Blood 94 1999 1273 1282
-
(1999)
Blood
, vol.94
, pp. 1273-1282
-
-
Rojnuckarin, P.1
Drachman, J.G.2
Kaushansky, K.3
-
27
-
-
0032925412
-
Historical perspective on the treatment of essential thrombocythemia and polycythemia vera
-
H.S. Gilbert Historical perspective on the treatment of essential thrombocythemia and polycythemia vera Semin Hematol 36 1999 19 22
-
(1999)
Semin Hematol
, vol.36
, pp. 19-22
-
-
Gilbert, H.S.1
-
28
-
-
0030307590
-
Hierarchical structure of human megakaryocyte progenitor cells
-
R. Hoffman, L.J. Murrav, J.C. Young, K.M. Luens, and E. Bruno Hierarchical structure of human megakaryocyte progenitor cells Stem Cells 14 suppl 1996 75 81
-
(1996)
Stem Cells
, vol.14
, Issue.SUPPL.
, pp. 75-81
-
-
Hoffman, R.1
Murrav, L.J.2
Young, J.C.3
Luens, K.M.4
Bruno, E.5
-
29
-
-
0035654985
-
Anagrelide metabolite induces thrombocytopenia in mice by inhibiting megakaryocyte maturation without inducing platelet aggregation
-
W.J. Lane, K. Hattori, and S. Dias Anagrelide metabolite induces thrombocytopenia in mice by inhibiting megakaryocyte maturation without inducing platelet aggregation Exp Hematol 29 2001 1417 1424
-
(2001)
Exp Hematol
, vol.29
, pp. 1417-1424
-
-
Lane, W.J.1
Hattori, K.2
Dias, S.3
-
30
-
-
0035865604
-
Long-term use of anagrelide in young patients with essential thrombocythemia
-
E.C. Storen, and A. Tefferi Long-term use of anagrelide in young patients with essential thrombocythemia Blood 97 2001 863 866
-
(2001)
Blood
, vol.97
, pp. 863-866
-
-
Storen, E.C.1
Tefferi, A.2
-
31
-
-
0029027918
-
Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors
-
M. Kobayashi, J.H. Laver, T. Kato, H. Miyazaki, and M. Ogawa Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors Blood 86 1995 2494 2499
-
(1995)
Blood
, vol.86
, pp. 2494-2499
-
-
Kobayashi, M.1
Laver, J.H.2
Kato, T.3
Miyazaki, H.4
Ogawa, M.5
-
32
-
-
0034772963
-
Simultaneous signalling through c-mpl, c-kit and CXCR4 enhances the proliferation and differentiation of human megakaryocyte progenitors: Possible roles of the PI3-K, PKC and MAPK pathways
-
H. Minamiguchi, T. Kimura, and Y. Urata Simultaneous signalling through c-mpl, c-kit and CXCR4 enhances the proliferation and differentiation of human megakaryocyte progenitors: possible roles of the PI3-K, PKC and MAPK pathways Br J Haematol 115 2001 175 185
-
(2001)
Br J Haematol
, vol.115
, pp. 175-185
-
-
Minamiguchi, H.1
Kimura, T.2
Urata, Y.3
|