Methodology for predicting oxygen transport on an intravenous membrane oxygenator combining computational and analytical models

Journal of Biomechanical Engineering

Volumn 127, Issue 7, 2005, Pages 1127-1140

  Guzmán, Amador M ^a   Escobar, Rodrigo A ^b   Amon, Cristina H ^c  

^a UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; CONCENTRATION (PROCESS); MASS TRANSFER;

FLOW MIXING; INTRAVENOUS MEMBRANE OXYGENATOR; OXYGEN TRANSPORT; PULSATING BALLOONS;

CELL MEMBRANES;

WATER;

ANALYTIC METHOD; ARTICLE; BLOOD; CALCULATION; COMPUTER MODEL; EXPERIMENTAL MODEL; FLOW RATE; FREQUENCY ANALYZER; INTRAVENOUS MEMBRANE OXYGENATOR; MATHEMATICAL MODEL; METHODOLOGY; OXYGEN TRANSPORT; OXYGENATOR; PREDICTION; THREE DIMENSIONAL IMAGING; TIME SERIES ANALYSIS; VALIDATION PROCESS;

BALLOON DILATATION; BIOLOGICAL TRANSPORT, ACTIVE; BLOOD VESSEL PROSTHESIS; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; MODELS, CARDIOVASCULAR; OXYGEN; OXYGENATORS, MEMBRANE; PULSATILE FLOW; THERAPY, COMPUTER-ASSISTED; VENA CAVA, INFERIOR;

EID: 30344475270     PISSN: 01480731     EISSN: None     Source Type: Journal    
DOI: 10.1115/1.2073669     Document Type: Article

References (34)

1. Federspiel, W. J., Golob, J. F., Merrill, T. L., Lund, L. W., Bultman, J. A., Frankowski, B. J., Watach, M., Litwak, K., and Hattler, B. G., 2000, "Ex vivo Testing of the Intravenous Membrane Oxygenator," ASAIO J., 46, pp. 261-267.
2. Anderson, H., Stremple, C., and Shapiro, M., 1993, "Extracorporeal Life Support for Adult Cardiorespiratory Failure," Surgery (St. Louis), 141, pp. 161-173.
3. Ichiba, S., and Bartlett, R. H., 1996, "Current Status of Extracorporeal Membrane Oxygenation for Severe Respiratory Failure," Artif. Organs, 20(2), pp. 120-123.
4. High, K. M., Snider, M. T., Richard, R., Russell, G. B., Stene, J. K., Campbell, D. B., Aufiero, T. X., and Thieme, G. A., 1992, "Clinical Trials of an Intravenous Oxygenator in Patients With Adult Respiratory Distress Syndrome," Anesthesiology. 77, pp. 856-863.
5. Fazzalari, F. L., Montoya, J. P., Bonnell, M. R., Blizz, D. W., Hirschl, R. B., and Bartlett, R. H., 1994, "The Development of an Implantable Artificial Lung," ASAIO J., 40, pp. M728-M731.
6. Vaslef, S. N., Cook, K. E., Leonard, R. J., Mockros, L. E. and Anderson, R. W., 1994, "Design and Evaluation of a New Pressure Loss. Implantable Artificial Lung," ASAIO J., 40, pp. M522-M526.
7. Vaslef, S. N., Leonard, R. J., Mockros, L. E. and Anderson, R. W., 1994, "Use of a Mathematical Model to Predict Oxygen Transfer Rates in Hollow Fiber Membrane Oxygenators," ASAIO J., 40, pp. 990-996.
8. Conrad, S. A. Bagley, A. Bagley, B., and Schaap, R. N., 1994, "Major Findings from the Clinical Trials of the Intravascular Oxygenator," Artif. Organs, 18, pp. 846-863.
9. Makarewicz, A. J., Mockros, L. E. and Mavroudis, C., 1996, "New Design for a Pumping Artificial Lung," ASAIO J., 46, pp. M615-M619.
10. Dierickx, P. W., De Somer, F., De Wachter, D. S., Van Nooten, G., and Verdonck, P. R., 2000, "Hydrodynamic Characteristics of Artificial Lungs," ASAIO J., 46, pp. 532-535.
11. Fiore, G. B., Costantino, M. L., Funero, R., and Montevecchi, F. M., 2000, "The Pumping Oxygenator: Design Criteria and First In Vitro Results," Artif. Organs, 24(10), pp. 797-807.
12. Kanamori, T., Niwa, M., Kawakami, H., Mori, Y., Nakaoga, S., Haraya, K., and Shinbo, T., 2000, "Estimate of Gas Transfer Rates of an Intravascular Membrane Oxygenator," ASAIO J., 46, pp. 612-619.
13. Hattler, B. G., Johnson, P. C., Sawzik, P. J., Shaffer, F. D., Klain, M., Lund, L. W., Reeder, G. D., Walters, F. R., Goode, J. S., and Borovetz, H. S., 1992. "Respiratory Dialysis: A New Concept in Pulmonary Support," ASAIO J., 38, pp. 322-325.
14. Hattler, B. G., Reeder, G. D., Sawzik, P. J., Lund, L. W., Walters, F. R., Shah, A. S., Rawleigh, J., Goode, J. S., Klain, M., and Borovetz, H. S., 1994, "Development of an Intravenous Membrane Oxygenator (IMO): Enhanced Intravenous Gas Exchange Through Convective Mixing of Blood Around Hollow Fiber Membranes," Artif. Organs, 18, pp. 806-812.
15. Macha, M., Federspiel, W. J., Lund, L. W., Sawzik, P. J., Litwak, P., Walters, F. R., Reeder, G. D., Borovetz, H. S., and Hattler, B. G., 1996, "Acute In Vivo Studies of the Pittsburgh Intravenous Membrane Oxygenator," ASAIO J., 42, pp. M609-M615.
16. Federspiel, W. J., Hout, M. S., Hewitt, T. J., Lund, L. W., Heinrich, S. A., Litwak, P., Walters, F. R., Reeder, G. D., Boravetz, H. S., and Hattler, B. G., 1997, "Development of a Low Flow Resistance Intravenous Oxygenator," ASAIO J., 43, pp. M725-M730.
17. Hewitt, T. J., Hattler, B. G., and Federspiel, W. J., 1998, "Experimental Evaluation of a Model for Oxygen Exchange in a Pulsating Intravascular Artificial Lung," Ann. Biomed. Eng., 26, pp. 166-178.
18. Federspiel, W. J., Golob, J. F., Frankowski, B. J., Merrill, T. L., Litwak, K., and Hattler, B. G., 1999, "Development and Testing of an Intravascular Artificial lung," Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 1, p. 345.
19. Federspiel, W. J., Hewitt, T. J., and Hattler, B. G., 2000, "Experimental Evaluation of a Model for Oxygen Exchange in a Pulsating Intravascular Artificial Lung," Ann. Biomed. Eng., 28, pp. 160-167.
20. Hout, M. S., Hattler, B. G., and Federspiel, W. J., 2000, "Validation of a Model for Flow-Dependent Carbon Dioxide Exchange in Artificial Lungs," Artif. Organs, 24(2), pp. 114-118.
21. Lund, L. W., Hattler, B. G., and Federspiel, W. J., 2002, "Gas Permeance Measurement of Hollow Fiber Membranes in Gas-Liquid Environment," AIChE J., 48(3), pp. 635-643.
22. Lund, L. W., Hattler, B. G., and Federspiel, W. J., 2002, "A Comparative In Vitro Hemolysys Study of a Pulsating Intravenous Artificial Lung," ASAIO J., 48(6), pp. 631-635.
23. Garcia, M. Y., Hattler, B. G., and Federspiel, W. J., 2002, "Effect of Vessel Compliance on the In-Vitro Performance of a Pulsating Respiratory Support Catherer," ASME J. Biomech. Eng., 124, pp. 56-62.
24. Lund, L. W., Hattler, B. G., and Federspiel, W. J., 2004, "Development of a Balloon Volume Sensor for Pulsating Balloon Catheters," AIChE J., 48(3), pp. 635-643.
25. Eash, H. J., Jones, H. M., Hattler, B. G., and Federspiel, W. J., 2004, "Evaluation of Plasma Resistant Hollow Fiber membranes for Artificial Lungs," ASAIO J., 50, pp. 491-497.
26. Guzmán, A. M., and Amon, C. H., 2000, "Flow and Mass Transfer Characteristics of an Intravenous Membrane Oxygenator: A Computational Study," Comput. Methods Biomech. Biomed. Eng., 3, pp. 147-166.
27. Guzmán, A. M., Escobar, R. A., Loyola, H. J., and Amon, C. H., 2000, "Pressure Drop and Mass Transfer in an Intravenous Membrane Oxygenator in a Pulsatile Flow Regime," Proceedings of NHTC'00, 34th National Heat Transfer Conference, August 20-22, Pittsburgh.
28. Guzman, A. M., Escobar, R. A., and Amon, C. H., 2000, "Effect of Curved Boundaries of an Intravenous Membrane Oxygenator on the Fluid Dynamics and Mass Transfer Characteristics," ASME 2000. Advances in Heat and Mass Transfer in Biotechnology-2000. E. P. Scott, J. C. Bischof, eds., HTD-Vol. 368/BED-Vol. 47, pp. 121-122.
29. Loyola, H. J., 2000, "Efecto de la Configuración Espacial y Numérica de las Microfibras en las Características del Flujo en un Oxigenador de Membrana Intravenoso," M.E. thesis, Universidad de Santiago de Chile, Chile.
30. Escobar, R. A., 2002, "Blood Flow and Oxygen Transport of an Intravenous Membrane Oxygenator in a 3D Model," M.S. in Mechanical Engineering thesis. Carnegie Mellon University, Pittsburgh.
31. Guzmán, A. M., Escobar, R. A., and Amon, C. H., 2005, "Flow Mixing Enhancement from Balloon Pulsations in an Intravenous Oxygenator," ASME J. Biomech. Eng., 127, pp. 400-415.
32. Guzmán, A. M., and Amon, C. H., 1994, "Transition to Chaos in Converging-Diverging Channel Flows: Ruelle-Takens-Newhouse Scenario," Phys. Fluids, 6(6), pp. 1994-2002.
33. Amon, C. H., Guzman, A. M., and Morel, B., 1996, "Lagrangian Chaos, Eulerian Chaos and Mixing Enhancement in Converging-Diverging Channel Flows," Phys. Fluids, 8(5), pp. 1192-1206.
34. Guzmán, A. M., and Amon, C. H., 1996, "Dynamical Flow Characterization of Transitional and Chaotic Regimes in Converging-Diverging Channels," J. Fluid Mech., 321, pp. 25-57.