Analysis of avian bone response to mechanical loading, Part Two: Development of a computational connected cellular network to study bone intercellular communication

Biomechanics and Modeling in Mechanobiology

Volumn 4, Issue 2-3, 2005, Pages 132-146

  Mi, Li Y ^a,b   Basu, Mitra ^a   Fritton, Susannah P ^a   Cowin, Stephen C ^a  

^a City University of New York   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; SENSITIVITY ANALYSIS; SHEAR STRESS;

AVIAN BONE RESPONSE; BONE CELLS; COMPUTATIONAL CONNECTED CELLULAR NETWORKS (CCCN);

BONE;

AVES;

ALGORITHM; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIRD; BONE; BONE DEVELOPMENT; CELL COMMUNICATION; COMPUTER SIMULATION; CYTOLOGY; MECHANICAL STRESS; PHYSIOLOGY; SHEAR STRENGTH; WEIGHT BEARING;

ALGORITHMS; ANIMALS; BIRDS; BONE AND BONES; BONE DEVELOPMENT; CELL COMMUNICATION; COMPUTER SIMULATION; MODELS, BIOLOGICAL; SHEAR STRENGTH; STRESS, MECHANICAL; WEIGHT-BEARING;

EID: 30344474607     PISSN: 16177959     EISSN: 16822978     Source Type: Journal    
DOI: 10.1007/s10237-004-0066-3     Document Type: Article

References (67)

1. Aarden EM, Burger EH, Nijweide PJ (1994) Function of osteocytes in bone. J Cell Biochem 55(3):287-299
2. Allen RE, Boxhorn LK (1989) Regulation of skeletal muscle satellite cell proliferation and differentiation by transforming growth factor-beta, insulin-like growth factor I, and fibroblast growth factor. J Cell Physiol 138(2):311-315
3. Anderson JA, Rosenfeld E (eds) (1988) Neurocomputing: Foundations of Research. MIT Press, Cambridge
4. Bloomfield SA (2001) Cellular and molecular mechanisms for the bone response to mechanical loading. Int J Sport Nutr Exerc Metab 11(Suppl):S128-S136
5. Burger EH, Klein-Nulend J (1999) Mechanotransduction in bone-role of the lacuno-canalicular network. FASEB J 13(Suppl):S101-S112
6. Chiba H, Sawada N, Oyamada M, Kojima T, Iba K, Ishii S, Mori M (1994) Hormonal regulation of connexin 43 expression and gap junctional communication in human osteoblastic cells. Cell Struct Funct 19(3):173-177
7. Chow JW, Fox S, Jagger CJ, Chambers TJ (1998) Role for para-thyroid hormone in mechanical responsiveness of rat bone. Am J Physiol 274(1 Pt 1):E146-E154
8. Churchland PS, Sejnowski TJ (1992) The computational brain. MIT Press, Cambridge
9. Cowin SC, Hegedus DH (1976) Bone remodeling I: theory of adaptive elasticity. J Elast 6(3):313-326
10. Cowin SC, Hart RT, Balser JR, Kohn DH (1985) Functional adaptation in long bones: establishing in vivo values for surface remodeling rate coefficients. J Biomech 18(9):665-684
11. Cowin SC, Moss-Salentijn L, Moss ML (1991) Candidates for the mechanosensory system in bone. J Biomech Eng 113: 191-197
12. Cowin SC, Weinbaum S, Zeng Y (1995) A case for bone canaliculi as the anatomical site of strain generated potentials. J Biomech 28(11):1281-1297
13. Currey JD (1960) Differences in the blood-supply of bone of different histological types. J Microsc Sci 101:351-370
14. Curtis TA, Ashrafi SH, Weber DF (1985) Canalicular communication in the cortices of human long bones. Anat Rec 212:336-344
15. D'Andrea P, Vittur F (1997) Propagation of intercellular Ca2 + waves in mechanically stimulated articular chondrocytes. FEBS Lett 400(1):58-64
16. Demer LL, Wortham CM, Dirksen ER, Sanderson MJ (1993) Mechanical stimulation induces intercellular calcium signaling in bovine aortic endothelial cells. Am J Physiol 264(6 Pt 2):H2094-H2102
17. Donahue HJ, McLeod KJ, Rubin CT, Andersen J, Grine EA, Hertzberg EL, Brink PR (1995) Cell-to-cell communication in osteoblastic networks: cell line-dependent hormonal regulation of gap junction function. J Bone Miner Res 10(6):881-889
18. Doty SB (1981) Morphological evidence of gap junctions between bone cells. Calcif Tissue Int 33:509-512
19. Duncan RL, Turner CH (1995) Mechanotransduction and the functional response of bone to mechanical strain. Calcif Tissue Int 57(5):344-358
20. Enomoto K, Furuya K, Yamagishi S, Maeno T (1992) Mechanically induced electrical and intracellular calcium responses in normal and cancerous mammary cells. Cell Calcium 13(8):501-511
21. Frost HM (1964) Dynamics of bone remodeling. In: Frost HM (ed) Bone biodynamics. Little and Brown, Boston
22. Frost HM (1986) Intermediary organization of the skeleton, vols I and II. CRC Press, Boca Raton
23. Garven HSD (1965) A Student's histology. Williams and Wilkins, Baltimore
24. Greene EA, Allen RE (1991) Growth factor regulation of bovine satellite cell growth in vitro. J Anim Sci 69(1):146-152
25. Gross TS, Edwards JL, McLeod KJ, Rubin CT (1997) Strain gradients correlate with sites of periosteal bone formation. Bone Miner 12:982-988
26. Gu Y, Publicover SJ (2000) Expression of functional metabotropic glutamate receptors in primary cultured rat osteoblasts. Cross-talk with N-methyl-D-aspartate receptors. J Biol Chem 275(44):34252-34259
27. Hart RT, Davy DT, Heiple KG (1984) A computational method for stress analysis of adaptive elastic materials with a view toward applications in strain-induced bone remodeling. J Biomech Eng 106(4):342-350
28. Haykin S (1999) Neural networks: a comprehensive foundation 2nd edn. Prentice Hall, Upper Saddle River
29. Hegedus DM, Cowin SC (1976) Bone remodeling, II: small strain adaptive elasticity. J Elast 6:337-352
30. Hinoi E, Fujimori S, Nakamura Y, Yoneda Y (2001) Group III metabotropic glutamate receptors in rat cultured calvarial osteoblasts. Biochem Biophys Res Commun 281 (2):341-346
31. Hsieh YF, Robling AG, Ambrosius WT, Burr DB, Turner CH (2001) Mechanical loading of diaphyseal bone in vivo: the strain threshold for an osteogenic response varies with location. J Bone Miner Res 16:2291-2297
32. Huggett JF, Mustafa A, O'neal L, Mason DJ (2002) The glutamate transporter GLAST-1 (EAAT-1) is expressed in the plasma membrane of osteocytes and is responsive to extracellular glutamate concentration. Biochem Soc Trans 30(Pt 6):890-893
33. Huiskes R, Weinans H, Grootenboer HJ, Dalstra M, Fudala B, Slooff TJ (1987) Adaptive bone-remodeling theory applied to prosthetic-design analysis. J Biomech 20:1135-1150
34. Inaoka T, Lean JM, Bessho T, Chow JW, Mackay A, Kokubo T, Chambers TJ (1995) Sequential analysis of gene expression after an osteogenic stimulus: c-fos expression is induced in osteocytes. Biochem Biophys Res Commun 217(1):264-270
35. Jagger CJ, Chow JW, Chambers TJ (1996) Estrogen suppresses activation but enhances formation phase of osteogenic response to mechanical stimulation in rat bone. J Clin Invest 98(10):2351-2357
36. Jeansonne BG, Feagin FF, McMinn RW, Shoemaker RL, Rehm WS (1979) Cell-to-cell communication of osteoblasts. J Dent Res 58(4):1415-1423
37. Jones SJ, Gray C, Sakamaki H, Arora M, Boyde A, Gourdie R, Green C (1993) The incidence and size of gap junctions between bone cells in rat calvaria. Anat Embryol (Berl) 187:343-352
38. Judex S, Gross TS, Zernicke RG (1997) Strain gradients correlate with sites of exercise-induced bone-forming surfaces in the adult skeleton. Bone Miner Res 12:1737-1745
39. Kamioka H, Honjo T, Takano-Yamamoto T (2001) A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy. Bone 28(2):145-149
40. Kasperk C, Fitzsimmons R, Strong D, Mohan S, Jennings J, Wergedal J, Baylink D (1990) Studies of the mechanism by which androgens enhance mitogenesis and differentiation in bone cells. J Clin Endocrinol Metab 71(5):1322-1329
41. Koch JC (1917) The laws of bone architecture. Am J Anat 21:177-298
42. Konieczynski DD, Truly MJ, Biewener AA (1998) Evaluation of a bone's in vivo 24-hour loading history for physical exercise compared with background loading. J Orthop Res 16(1):29-37
43. Lean JM, Mackay AG, Chow JW, Chambers TJ (1996) Osteocytic expression of mRNA for c-fos and IGF-I: an immediate early gene response to an osteogenic stimulus. Am J Physiol 270(6 Pt 1):E937-E945
44. Lecanda F, Towler DA, Ziambaras K, Cheng SL, Koval M, Steinberg TH, Civitelli R (1998) Gap junctional communication modulates gene expression in osteoblastic cells. Mol Biol Cell 9(8):2249-2258
45. Mason DJ, Suva LJ, Genever PG, Patton AJ, Steuckle S, Hillam RA, Skerry TM (1997) Mechanically regulated expression of a neural glutamate transporter in bone: a role for excitatory amino acids as osteotropic agents? Bone 20(3):199-205
46. Mattheck C, Huber-Betzer H (1991) CAO: computer simulation of adaptive growth in bones and trees. In: Held KD, Brebbia CA, Ciskowski RD (eds) Computers in biomedicine. Computational Mechanics Publicatins, Southampton
47. Mikuni-Takagaki Y (1999) Mechanical responses and signal transduction pathways in stretched osteocytes. J Bone Miner Metab 17(1):57-60
48. Moss ML (1991) Bone as a connected cellular network: modeling and testing. In: Ross G (ed) Topics in biomedical engineering. Pergamon, New York
49. Palumbo C, Palazzini S, Marotti G (1993) Morphological study of intercellular junctions during osteocyte differentiation. Bone 11(6):401-406
50. Patton AJ, Genever PG, Birch MA, Suva LJ, Skerry TM (1998) Expression of an N-methyl-D-aspartate-type receptor by human and rat osteoblasts and osteoclasts suggests a novel glutamate signaling pathway in bone. Bone 22(6):645-649
51. Prendergast PJ, Taylor D (1994) Prediction of bone adaptation using damage accumulation. J Biomech 27(8):1067-1076
52. Rasmussen H, Bordier P (1975) The physiological and cellular basis of metabolic bone disease. Williams and Wilkins, Baltimore
53. Rawlinson SC, Pitsillides AA, Lanyon LE (1996) Involvement of different ion channels in osteoblasts' and osteocytes' early responses to mechanical strain. Bone 19(6):609-614
54. Riedmiller M, Braun H (1993) A direct adaptive method for faster backpropagation learning: the RPROP algorithm. In: Proceedings of the IEEE International Conference on Neural Networks, pp 586-591
55. Romanello M, Veronesi V, D'Andrea P (2003) Mechanosensitivity and intercellular communication in HOBIT osteoblastic cells: a possible role for gap junction hemichannels. Biorheology 40(1-3):119-121
56. Rubin CT, Lanyon LE (1987) Osteoregulatory nature of mechanical stimuli: function as a determinant for adaptive remodeling in bone. J Orthop Res 5(2):300-310
57. Saunders MM, You J, Trosko JE, Yamasaki H, Li Z, Donahue HJ, Jacobs CR (2001) Gap junctions and fluid flow response in MC3T3-E1 cells. Am J Physiol Cell Physiol 281(6):C1917-C1925
58. Seino Y (1994) Cytokines and growth factors which regulate bone cell function. Acta Astronaut 33:131-136
59. Spencer GJ, Genever PG (2003) Long-term potentiation in bone-role for glutamate in strain-induced cellular memory?. BMC Cell Biol 4(1):9
60. Turner CH (1991) Toward a mathematical description of bone biology: the principle of cellular accommodation. Calcif Tissue Int 65:466-481
61. Turner CH, Robling AG, Duncan RL, Burr DB (2002) Do bone cells behave like a neuronal network? Calcif Tissue Int 70(6):435-442
62. Weinbaum S, Cowin SC, Zeng Y (1994) A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses. J Biomech 27:339-360
63. Wolff J (1892) Das Gesetz der Transformation der Knochen. Hirschwald, Berlin
64. Wolff J (1986) The law of bone remodelling. Springer, Berlin Heidelberg NewYork
65. Yellowley CE, Li Z, Zhou Z, Jacobs CR, Donahue HJ (2001) Functional gap junctions between osteocytic and osteoblastic cells. J Bone Miner Res 15(2):209-217
66. You L, Cowin SC, Schaffler MB, Weinbaum S (2001) A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix. J Biomech 34(11):1375-1386
67. Ypey DL, Weidema AF, Hold KM, Van der Laarse A, Ravesloot JH, Van Der Plas A, Nijweide PJ (1992) Voltage, calcium, and stretch activated ionic channels and intracellular calcium in bone cells. J Bone Miner Res 7(Suppl 2):S377-S387