Long-term potentiation in bone - A role for glutamate in strain-induced cellular memory?

BMC Cell Biology

Volumn 4, Issue , 2003, Pages

  Spencer, Gary I ^a   Genever, Paul G ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ARTICLE; BONE CELL; BONE DENSITY; BONE DEVELOPMENT; BONE DISEASE; BONE MASS; BONE MINERAL; BONE STRUCTURE; BRAIN ELECTROPHYSIOLOGY; CELL COMMUNICATION; CELL FUNCTION; CENTRAL NERVOUS SYSTEM; DRUG TARGETING; HUMAN; HYPOTHESIS; IMMOBILIZATION; IN VIVO STUDY; LONG TERM POTENTIATION; MECHANICAL STRESS; MECHANOTRANSDUCTION; MODULATION; NEUROTRANSMISSION; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; WEIGHTLESSNESS;

BONE AND BONES; BONE REMODELING; GLUTAMATES; HUMANS; LONG-TERM POTENTIATION; MEMORY; MODELS, BIOLOGICAL; OSTEOBLASTS; STRESS, MECHANICAL;

EID: 2342494766     PISSN: 14712121     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2121-4-9     Document Type: Article

References (36)

1. Chenu C, Serre CM, Raynal C, Burt-Pichat B and Delmas PD: Glutamate receptors are expressed by bone cells and are involved in bone resorption Bone 1998, 22:295-299.
2. Patton AJ, Genever PG, Birch MA, Suva LJ and Skerry TM: Expression of an N-methyl-D-aspartate-type receptor by human and rat osteoblasts and osteoclasts suggests a novel glutamate signaling pathway in bone Bone 1998, 22:645-649.
3. Laketic-Ljubojevic I, Suva LJ, Maathuis FJ, Sanders D and Skerry TM: Functional characterization of N-methyl-D-aspartic acid-gated channels in bone cells Bone 1999, 25:631-637.
4. Peet NM, Grabowski PS, Laketic-Ljubojevic I and Skerry TM: The glutamate receptor antagonist MK801 modulates bone resorption in vitro by a mechanism predominantly involving osteoclast differentiation FASEB J 1999, 13:2179-2185.
5. Itzstein C, Espinosa L, Delmas PD and Chenu C: Specific antagonists of NMDA receptors prevent osteoclast sealing zone formation required for bone resorption Biochem Biophys Res Commun 2000, 268:201-209.
6. Gu Y and Publicover SJ: Expression of functional metabotropic glutamate receptors in primary cultured rat osteoblasts. Cross-talk with N-methyl-D-aspartate receptors J Biol Chem 2000, 275:34252-34259.
7. Hinoi E, Fujimori S, Nakamura Y and Yoneda Y: Group III metabotropic glutamate receptors in rat cultured calvarial osteoblasts Biochem Biophys Res Commun 2001, 281:341-346.
8. Bhangu PS, Genever PG, Spencer GJ, Grewal TS and Skerry TM: Evidence for targeted vesicular glutamate exocytosis in osteoblasts Bone 2001, 29:16-23.
9. Genever PG and Skerry TM: Regulation of spontaneous glutamate release activity in osteoblastic cells and its role in differentiation and survival: evidence for intrinsic glutamatergic signaling in bone FASEB J 2001, 15:1586-1588.
10. Spencer GJ, Bhangu PS, Genever PG, Grewal TS and Skerry TM: Functional GLAST; An essential molecular link in glutamatergic signalling during osteoblast differentiation J Bone Miner Res 1999, 14(6):O12.
11. Birch MA, Genever PG, Laketic-Ljubojevic I, Patton AJ, Peet NM and Skerry TM: Glutamate receptor activation is necessary for bone formation in vitro J Bone Miner Res 1997, 12(9):O10.
12. Fukunaga K, Stoppini L, Miyamoto E and Muller D: Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II J Biol Chem 1993, 268:7863-12.
13. Fukunaga K and Miyamoto E: A working model of CaM kinase II activity in hippocampal long-term potentiation and memory Neurosci Res 2000, 38:3-17.
14. Malenka RC, Kauer JA, Perkel DJ, Mauk MD, Kelly PT and Nicoll RA et al.: An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation Nature 1989, 340:554-557.
15. Malinow R, Schulman H and Tsien RW: Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP Science 1989, 245:862-866.
16. Silva AJ, Stevens CF, Tonegawa S and Wang Y: Deficient hippocampal long-term potentiation in alpha-calcium- calmodulin kinase II mutant mice Science 1992, 257:201-206.
17. Lledo PM, Hjelmstad GO, Mukherji S, Soderling TR, Malenka RC and Nicoll RA: Calcium/calmodulin-dependent kinase II and long-term potentiation enhance synaptic transmission by the same mechanism Proc Natl Acad Sci U S A 1995, 92:11175-11179.
18. Pettit DL, Perlman S and Malinow R: Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons Science 1994, 266:1881-1885.
19. Hayashi Y, Shi SH, Esteban JA, Piccini A, Poncer JC and Malinow R: Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction Science 2000, 287:2262-2267.
20. Derkach V, Barria A and Soderling TR: Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors Proc Natl Acad Sci U S A 1999, 96:3269-3274.
21. Chen L, Chetkovich DM, Petralia RS, Sweeney NT, Kawasaki Y and Wenthold RJ et al.: Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms Nature 2000, 408:936-943.
22. Nakagawa T and Sheng M: Neurobiology. A stargazer foretells the way to the synapse Science 2000, 290:2270-2271.
23. Rodan GA: Bone mass homeostasis and bisphosphonate action Bone 1997, 20:1-4.
24. Hillam RA and Skerry TM: Inhibition of bone resorption and stimulation of formation by mechanical loading of the modeling rat ulna in vivo J Bone Miner Res 1995, 10:683-689.
25. Bourrin S, Palle S, Pupier R, Vico L and Alexandre C: Effect of physical training on bone adaptation in three zones of the rat tibia J Bone Miner Res 1995, 10:1745-1752.
26. Heinonen A, Oja P, Kannus P, Sievanen H, Haapasalo H and Manttari A et al.: Bone mineral density in female athletes representing sports with different loading characteristics of the skeleton Bone 1995, 17:197-203.
27. Lanyon L and Skerry TM: Postmenopausal osteoporosis as a failure of bone's adaption to functional loading: A Hypothesis J Bone Miner Res 2001, 16:1937-1947.
28. Pead MJ, Skerry TM and Lanyon LE: Direct transformation from quiescence to bone formation in the adult periosteum following a single brief period of bone loading J Bone Miner Res 1988, 3:647-656.
29. Robling AG, Burr DB and Turner CH: Partitioning a daily mechanical stimulus into discrete loading bouts improves the osteogenic response to loading J Bone Miner Res 2000, 15:1596-1602.
30. Robling AG, Hinant FM, Burr DB and Turner CH: Improved bone structure and strength after long-term mechanical loading is greatest if loading is separated into short bouts J Bone Miner Res 2002, 17:1545-1554.
31. Srinivasan S, Weimer DA, Agans SC, Bain SD and Gross TS: Low-magnitude mechanical loading becomes osteogenic when rest is inserted between each load cycle J Bone Miner Res 2002, 17:1613-1620.
32. Hsieh YF and Turner CH: Effects of loading frequency on mechanically induced bone formation J Bone Miner Res 2001, 16:918-924.
33. Rubin CT and Lanyon LE: Regulation of bone formation by applied dynamic loads J Bone Joint Surg Am 1984, 66:397-402.
34. Spencer GJ, Grewal TS, Genever PG and Skerry TM: Long-term potentiation in bone: A cellular basis of memory in osteoblasts Bone 2001, 28(5S):S65-OR72.
35. Spencer GJ, Grewal TS, Genever TM and Skerry : Calcium dependent protein kinase II activity is obligate for bone formation in vitro J Bone Miner Res 2001, 16(6):OC25.
36. Taylor AF, Brabbs AC, Peet NM, Laketic-Ljubojevic I, Dobson KR and Skerry TM: Bone formation/resorption and osteoblast/adipocyte plasticity mediated by AMPA/kainate glutamate receptors in vitro and in vivo J Bone Miner Res 2000, 15(S1):SA222.