Evaluation of the validity of a maximum likelihood adaptive staircase procedure for measurement of olfactory detection threshold in mice

Chemical Senses

Volumn 31, Issue 1, 2006, Pages 9-26

  Clevenger, Amy C ^a   Restrepo, Diego ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

CNGA2; Knockout mice; Maximum likelihood; Odor detection; Olfactometer; Operant conditioning

Indexed keywords

CYCLIC NUCLEOTIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; INSTRUMENTAL CONDITIONING; KNOCKOUT MOUSE; MALE; MAXIMUM LIKELIHOOD METHOD; METHODOLOGY; MONTE CARLO METHOD; MOUSE; NONHUMAN; OLFACTOMETRY; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; RODENT; SEQUENTIAL ANALYSIS; SIGNAL DETECTION; SMELLING; TASK PERFORMANCE; VALIDITY;

ANIMALS; COMPUTER SIMULATION; DIAGNOSTIC TECHNIQUES AND PROCEDURES; ION CHANNELS; MICE; MICE, KNOCKOUT; MONTE CARLO METHOD; ODORS; OLFACTION DISORDERS; OLFACTORY PATHWAYS; PSYCHOMOTOR PERFORMANCE; SENSORY THRESHOLDS;

ANIMALIA; RODENTIA;

EID: 30344470493     PISSN: 0379864X     EISSN: 14643553     Source Type: Journal    
DOI: 10.1093/chemse/bjj001     Document Type: Article

References (35)

1. Apfelbach, R., Weiler, E., Asselbergs, W.F., Polak, E.H. and Slotnick, B. (1998) Selective and reversible reduction of odor sensitivity in the rat by concanavalin A. Physiol Behav., 65, 513-516.
2. Apter, A.J., Gent, J.F. and Frank, M.E. (1999) Fluctuating olfactory sensitivity and distorted odor perception in allergic rhinitis. Arch. Otolaryngol. Head Neck Surg., 125, 1005-1010.
3. Baker, H., Cummings, D.M., Munger, S.D., Margolis, J.W., Franzen, L., Reed, R.R. and Margolis, F.L. (1999) Targeted deletion of a cyclic nucleotide-gated channel subunit (OCNC1): Biochemical and morphological consequences in adult mice. J. Neurosci., 19, 9313-9321.
4. Bodyak, N. and Slotnick, B. (1999) Performance of mice in an automated olfactometer: Odor detection, discrimination and odor memory. Chem. Senses, 24, 637-645.
5. Brunet, L.J., Gold, G.H. and Ngai, J. (1996) General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron, 17, 681-693.
6. Buck, L.B. (2000) The molecular architecture of odor and pheromone sensing in mammals. Cell, 100, 611-618.
7. Cain, W.S., Gent, J.F., Catalanotto, F.A. and Goodspeed, R.B. (1983) Clinical evaluation of olfaction. Am. J. Otolaryngol., 4, 252-256.
8. Cometto-Muniz, J.E., Cain, W.S. and Abraham, M.H. (2003) Quantification of chemical vapors in chemosensory research. Chem. Senses, 28, 467-477.
9. Harvey, L.O. Jr (1986) Efficient estimation of sensory thresholds. Behav. Res. Meth. Instrum. Comput., 18, 623-632.
10. Harvey, L.O. Jr (1997) Efficient estimation of sensory thresholds with ML-PEST. Spat. Vision, 11, 121-128.
11. Krantz, D.H. (1969) Threshold theories of signal detection. Psychol. Rev., 76, 308-324.
12. Lin, D.M., Wang, F., Lowe, G., Gold, G.H., Axel, R., Ngai, J. and Brunet, L. (2000) Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity. Neuron, 26, 69-80.
13. Lin, W., Arellano, J., Slotnick, B. and Restrepo, D. (2004) Odors detected by mice deficient in olfactory cyclic nucleotide-gated channel subunit A2 stimulate the main olfactory system. J. Neurosci., 24, 3703-3710.
14. Linschoten, M.R., Harvey, L.O. Jr, Eller, P.M. and Jafek, B.W. (2001) Fast and accurate measurement of taste and smell thresholds using a maximum-likelihood adaptive staircase procedure. Percept. Psychophys., 63, 1330-1347.
15. Lu, Z.L. and Dosher, B.A. (2004) Perceptual learning retunes the perceptual template in foveal orientation identification. J. Vision, 4, 44-56.
16. Maloney, L.T. (1990) Confidence intervals for the parameters of psychometric functions. Percept. Psychophys., 47, 127-134.
17. McLean, J.H. and Harley, C.W. (2004) Olfactory learning in the rat pup: a model that may permit visualization of a mammalian memory trace. Neuroreport, 15, 1691-1697.
18. Pho, V., Butman, M.L. and Cherry, J.A. (2005) Type 4 phosphodiesterase inhibition impairs detection of low odor concentrations in mice. Behav. Brain Res., 161, 245-253.
19. Pietras, R.J. and Moulton, D.G. (1974) Hormonal influences on odor detection in rats: Changes associated with the estrous cycle, pseudopregnancy, ovariectomy and administration of testosterone propionate. Physiol. Behav., 12, 475-491.
20. Press, W.H., Teukolsky, S.A., Vettering, W.T. and Flannery, B.P. (1992) Numerical Recipes in C. Cambridge University Press, Cambridge, UK.
21. Salcedo, E., Zhang, C., Kronberg, E. and Restrepo, D. (2005) Analysis of training-induced changes in ethyl acetate odor maps using a new computational tool to map the glomerular layer of the olfactory bulb. Chem. Senses, 30, 615-626.
22. Slotnick, B.M., Bell, G.A., Panhuber, H. and Laing, D.G. (1997) Detection and discrimination of propionic acid after removal of its 2-DG identified major focus in the olfactory bulb: A psychophysical analysis. Brain Res., 762, 89-96.
23. Slotnick, B.M. and Schoonover, F.W. (1993) Olfactory sensitivity of rats with transection of the lateral olfactory tract. Brain Res., 616, 132-137.
24. Terutwein, B. and Strasburger, H. (1999) Fitting the psychometric function. Percept. Psychophys., 61, 87-106.
25. Vedin, V., Slotnick, B. and Berghard, A. (2004) Zonal ablation of the olfactory sensory neuroepithelium of the mouse: Effects on odorant detection. Eur. J. Neurosci., 20, 1858-1864.
26. Watson, A.B. and Pelli, D.G. (1983) QUEST: A Bayesian adaptive psychometric method. Percept. Psychophys., 33, 113-120.
27. Wetherhill, G.B. and Levitt, H. (1965) Sequential estimation of points on a psychometric function. Br. J. Math. Stat. Psychol., 18, 1-10.
28. Wichmann, F.A. and Hill, N.J. (2001) The psychometric function: I. Fitting, sampling, and goodness of fit. Percept. Psychophys., 63, 1293-1313.
29. Wilson, D.A. and Stevenson, R.J. (2003) Olfactory perceptual learning: the critical role of memory in odor discrimination. Neurosci. Biobehav. Rev., 27, 307-328.
30. Witte, R.S. and Kipke, D.R. (2005) Enhanced contrast sensitivity in auditory cortex as cats learn to discriminate sound frequencies. Brain Res. Cogn. Brain Res., 23, 171-184.
31. Xu, F.Q., Greer, C.A. and Shepherd, G.M. (2000) Odor maps in the olfactory bulb. J. Comp. Neurol., 422, 489-495.
32. Youngentob, S.L. and Margolis, F.L. (1999) OMP gene deletion causes an elevation in behavioral threshold sensitivity. Neuroreport, 10, 15-19.
33. Youngentob, S.L., Pyrski, M.M. and Margolis, F.L. (2004) Adenoviral vector-mediated rescue of the OMP-null behavioral phenotype: Enhancement of odorant threshold sensitivity. Behav. Neurosci., 118, 636-642.
34. Youngentob, S.L., Schwob, J.E., Sheehe, P.R. and Youngentob, L.M. (1997) Odorant threshold following methyl bromide-induced lesions of the olfactory epithelium. Physiol. Behav., 62, 1241-1252.
35. Zheng, C., Feinstein, P., Bozza, T., Rodriguez, I. and Mombaerts, P. (2000) Peripheral olfactory projections are differentially affected in mice deficient in a cyclic nucleotide-gated channel subunit. Neuron, 26, 81-91. Accepted October 24, 2005