Mild copper deficiency alters gene expression of proteins involved in iron metabolism

Blood Cells, Molecules, and Diseases

Volumn 36, Issue 1, 2006, Pages 15-20

  Auclair, Sylvain ^a   Feillet Coudray, Christine ^a   Coudray, Charles ^a   Schneider, Susanne ^b   Muckenthaler, Martina U ^c   Mazur, Andrzej ^a  

^a CRNH AUVERGNE   (France)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Anemia; Copper; Gene expression; Iron; Mouse

Indexed keywords

CD71 ANTIGEN; CERULOPLASMIN; COMPLEMENTARY DNA; COPPER; FERROCHELATASE; FERROPORTIN 1; HEME OXYGENASE; HEPCIDIN; MESSENGER RNA; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; TRANSFERRIN RECEPTOR 2;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; COPPER DEFICIENCY; COPPER METABOLISM; DNA MICROARRAY; DUODENUM; GENE EXPRESSION; HEMATOLOGICAL PARAMETERS; IRON METABOLISM; IRON OVERLOAD; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN;

ANEMIA, IRON-DEFICIENCY; ANIMALS; COPPER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEME; IRON; IRON OVERLOAD; MALE; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SPECIFICITY;

ANIMALIA;

EID: 30344458848     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2005.11.003     Document Type: Article

References (39)

1. J. Boccio, J. Salgueiro, A. Lysionek, M. Zubillaga, R. Weill, C. Goldman, and R. Caro Current knowledge of iron metabolism Biol. Trace Elem. Res. 92 2003 189 212
2. J. Chung, and M. Wessling-Resnick Molecular mechanisms and regulation of iron transport Crit. Rev. Clin. Lab. Sci. 40 2003 151 182
3. A.T. McKie, D. Barrow, G.O. Latunde-Dada, A. Rolfs, G. Sager, E. Mudaly, M. Mudaly, C. Richardson, D. Barlow, A. Bomford, T.J. Peters, K.B. Raja, S. Shirali, M.A. Hediger, F. Farzaneh, and R.J. Simpson An iron-regulated ferric reductase associated with the absorption of dietary iron Science 291 2001 1755 1759
4. H. Gunshin, B. Mackenzie, U.V. Berger, Y. Gunshin, M.F. Romero, W.F. Boron, S. Nussberger, J.L. Gollan, and M.A. Hediger Cloning and characterization of a mammalian proton-coupled metal-ion transporter Nature 388 1997 482 488
5. S. Vidal, A.M. Belouchi, M. Cellier, B. Beatty, and P. Gros Cloning and characterization of a second human NRAMP gene on chromosome 12q13 Mamm. Genome 6 1995 224 230
6. A.T. McKie, P. Marciani, A. Rolfs, K. Brennan, K. Wehr, D. Barrow, S. Miret, A. Bomford, T.J. Peters, F. Farzaneh, M.A. Hediger, M.W. Hentze, and R.J. Simpson A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation Mol. Cell 5 2000 299 309
7. R.E. Fleming, and W.S. Sly Mechanisms of iron accumulation in hereditary hemochromatosis Annu. Rev. Physiol. 64 2002 663 680
8. C.D. Vulpe, Y.M. Kuo, T.L. Murphy, L. Cowley, C. Askwith, N. Libina, J. Gitschier, and G.J. Anderson Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse Nat. Genet. 21 1999 195 199
9. P.G. Reeves, and L.C. DeMars Copper deficiency reduces iron absorption and biological half-life in male rats J. Nutr. 134 2004 1953 1957
10. P.G. Reeves, N.V. Ralston, J.P. Idso, and H.C. Lukaski Contrasting and cooperative effects of copper and iron deficiencies in male rats fed different concentrations of manganese and different sources of sulfur amino acids in an AIN-93G-based diet J. Nutr. 134 2004 416 425
11. K. Yamamoto, K. Yoshida, Y. Miyagoe, A. Ishikawa, K. Hanaoka, S. Nomoto, K. Kaneko, S. Ikeda, and S. Takeda Quantitative evaluation of expression of iron-metabolism genes in ceruloplasmin-deficient mice Biochim. Biophys. Acta 1588 2002 195 202
12. J.R. Prohaska, and W.W. Wells Copper deficiency in the developing rat brain: a possible model for Menkes' steely-hair disease J. Neurochem. 23 1974 91 98
13. D.I. Paynter, R.J. Moir, and E.J. Underwood Changes in activity of the Cu-Zn superoxide dismutase enzyme in tissues of the rat with changes in dietary copper J. Nutr. 109 1979 1570 1576
14. S. Okahata, Y. Nishi, S. Hatano, Y. Kobayashi, and T. Usui Changes in erythrocyte superoxide dismutase in a patient with copper deficiency Eur. J. Pediatr. 134 1980 121 124
15. D.M. Williams, R.E. Lynch, G.R. Lee, and G.E. Cartwright Superoxide dismutase activity in copper-deficient swine Proc. Soc. Exp. Biol. Med. 149 1975 534 536
16. C.J. Gubler, M.E. Lahey, M.S. Chase, G.E. Cartwright, and M.M. Wintrobe Studies on copper metabolism. III. The metabolism of iron in copper deficient swine Blood 7 1952 1075 1092
17. M.E. Lahey, C.J. Gubler, M.S. Chase, G.E. Cartwright, and M.M. Wintrobe Studies on copper metabolism. II. Hematologic manifestations of copper deficiency in swine Blood 7 1952 1053 1074
18. D.E. Coppen, and N.T. Davies Studies on the roles of apotransferrin and caeruloplasmin (EC 1.16.3.1) on iron absorption in copper-deficient rats using an isolated vascularly- and luminally-perfused intestinal preparation Br. J. Nutr. 60 1988 361 373
19. C. Thomas, and P.S. Oates Copper deficiency increases iron absorption in the rat Am. J. Physiol.: Gastrointest. Liver Physiol. 285 2003 G789 G795
20. F.W. Sunderman Jr., and S. Nomoto Measurement of human serum ceruloplasmin by its p-phenylenediamine oxidase activity Clin. Chem. 16 1970 903 910
21. A.L. Foy, H.L. Williams, S. Cortell, and M.E. Conrad A modified procedure for the determination of nonheme iron in tissue Anal. Biochem. 18 1967 559 563
22. R.J. Simpson, M. Lombard, K.B. Raja, R. Thatcher, and T.J. Peters Iron absorption by hypotransferrinaemic mice Br. J. Haematol. 78 1991 565 570
23. M. Muckenthaler, C.N. Roy, A.O. Custodio, B. Minana, J. deGraaf, L.K. Montross, N.C. Andrews, and M.W. Hentze Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis Nat. Genet. 34 2003 102 107
24. M. Muckenthaler, A. Richter, N. Gunkel, D. Riedel, M. Polycarpou-Schwarz, S. Hentze, M. Falkenhahn, W. Stremmel, W. Ansorge, and M.W. Hentze Relationships and distinctions in iron-regulatory networks responding to interrelated signals Blood 101 2003 3690 3698
25. M.W. Hentze, M.U. Muckenthaler, and N.C. Andrews Balancing acts: molecular control of mammalian iron metabolism Cell 117 2004 285 297
26. A. Krause, S. Neitz, H.J. Magert, A. Schulz, W.G. Forssmann, P. Schulz-Knappe, and K. Adermann LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity FEBS Lett. 480 2000 147 150
27. C.H. Park, E.V. Valore, A.J. Waring, and T. Ganz Hepcidin, a urinary antimicrobial peptide synthesized in the liver J. Biol. Chem. 276 2001 7806 7810
28. G. Nicolas, M. Bennoun, A. Porteu, S. Mativet, C. Beaumont, B. Grandchamp, M. Sirito, M. Sawadogo, A. Kahn, and S. Vaulont Severe iron deficiency anemia in transgenic mice expressing liver hepcidin Proc. Natl. Acad. Sci. U. S. A. 99 2002 4596 4601
29. G. Nicolas, C. Chauvet, L. Viatte, J.L. Danan, X. Bigard, I. Devaux, C. Beaumont, A. Kahn, and S. Vaulont The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation J. Clin. Invest. 110 2002 1037 1044
30. I. Bureau, C.G. Lewis, and M. Fields Effect of hepatic iron on hypercholesterolemia and hypertriacylglycerolemia in copper-deficient fructose-fed rats Nutrition 14 1998 366 371
31. M. Fields, C.G. Lewis, M. Lure, and W.E. Antholine The influence of gender on developing copper deficiency and on free radical generation of rats fed a fructose diet Metabolism 41 1992 989 994
32. M. Fields, R.J. Ferretti, S. Reiser, and J.C. Smith Jr. The severity of copper deficiency in rats is determined by the type of dietary carbohydrate Proc. Soc. Exp. Biol. Med. 175 1984 530 537
33. M.A. Johnson, and S.S. Hove Development of anemia in copper-deficient rats fed high levels of dietary iron and sucrose J. Nutr. 116 1986 1225 1238
34. E. Rock, E. Gueux, A. Mazur, C. Motta, and Y. Rayssiguier Anemia in copper-deficient rats: role of alterations in erythrocyte membrane fluidity and oxidative damage Am. J. Physiol. 269 1995 C1245 C1249
35. G.M. Bartoli, P. Palozza, and E. Piccioni Enhanced sensitivity to oxidative stress in Cu,ZnSOD depleted rat erythrocytes Biochim. Biophys. Acta 1123 1992 291 295
36. Z.L. Harris Aceruloplasminemia J. Neurol. Sci. 207 2003 108 109
37. P.G. Reeves, and L.C. Demars Repletion of copper-deficient rats with dietary copper restores duodenal hephaestin protein and iron absorption Exp. Biol. Med. (Maywood) 230 2005 320 325
38. H. Chen, Z.K. Attieh, T. Su, B.A. Syed, H. Gao, R.M. Alaeddine, T.C. Fox, J. Usta, C.E. Naylor, R.W. Evans, A.T. McKie, G.J. Anderson, and C.D. Vulpe Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice Blood 103 2004 3933 3939
39. J. Chung, J.R. Prohaska, and M. Wessling-Resnick Ferroportin-1 is not upregulated in copper-deficient mice J. Nutr. 134 2004 517 521