Cooler biologically compatible core body temperatures may prolong longevity and combat neurodegenerative disorders

Medical Hypotheses

Volumn 66, Issue 3, 2006, Pages 636-642

  Salerian, Alen J ^a   Saleri, Nansen G ^a  

^a Washington Center for Psychiatry   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CHOLINESTERASE INHIBITOR; CYCLOPHOSPHAMIDE; RADICAL; TACRINE;

AGING; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; CALORIC RESTRICTION; CELL DAMAGE; CORE TEMPERATURE; DEGENERATIVE DISEASE; DISEASE CLASSIFICATION; DISEASE COURSE; HEART INFARCTION; HUMAN; INDUCED HYPOTHERMIA; INFLAMMATION; LONGEVITY; METABOLIC RATE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REVIEW; SLEEP; STATISTICAL ANALYSIS; STROKE; TEMPERATURE ACCLIMATIZATION; TEMPERATURE DEPENDENCE; THERMOREGULATION;

EID: 30344440371     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2005.07.021     Document Type: Article

References (31)

1. G.A. Cortopressi, and E. Wang Mech Aging Dev 91 1996 211 218
2. M.Y. Savage, and G.B. West Biological scaling and physiological time: bio-medical applications. Chapter 2: Complex systems in science and medicine 2005 Kluwer Academic-Plenum Publishers New York
3. S. Arrhenius Z Phys Chem 4 1889 226 248
4. J.F. Gillooly, J.H. Brown, G.B. West, V.M. Savage, and E.L. Charnoc Effects of size and temperature on metabolic rate Science 293 2001 2248 2251
5. R.S. Sohal Relationship between anti-oxidants, pro-oxidants and the aging process Ann NY Acad Sci 663 1 1992 74 84
6. Harman D. Aging: a theory based on free-radical and radiation chemistry', July 1955, report, University of California Radiation Laboratory.
7. S. Loft, A. Astrop, B. Buemann, and H.E. Poulsen Oxidative DNA damage correlates with oxygen consumption in humans Fed Am Soc Expe Biol J 8 1994 534 537
8. G.S. Roth, M.A. Lane, D.K. Ingram, J.A. Mattison, D. Elahi, J.D. Tobin, D. Muller, and E.J. Metter Biomarkers of caloric restriction may predict longevity in humans Science 297 2002 811
9. C.V. Gisolfi, and F. Mora The hot brain 2000 The MIT Press
10. Clancy Dietary restriction in long-lived dwarf flies Science 296 2002 319
11. M.P. Mattson, W. Duan, and J. Lee Suppression of brain aging and nuero-degenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms Aging Dev 122 77 2001 757 778
12. H.Y. Cohen, C. Miller, K.J. Bitterman, N.R. Wall, B. Hekking, B. Kessler, K.T. Howitz, M. Gorospe, R. DeCabo, and D.A. Sinclair Calorie restriction promotes mammalian cell Science June 2004
13. B. Wilcox How much should we eat? The association between energy intake and mortality in a 36-year follow-up study of Japanese-Americans J Gerontol Biol Sci September 2004
14. R. Weindruch, and R.L. Walford The retardation of aging and disease by dietary restriction 1988 Charles C. Thomas Publishers Springfield, IL
15. M.A. Lane, D.J. Baer, W.V. Rumpler, R. Weidruch, D.K. Ingram, E.M. Tilmont, R.G. Cutler, and G.S. Roth Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents Proc Natl Acad Sci USA 93 9 1996 4159 4164
16. Kusumoto Y, Lomakin A, Teplow DB, Benedek, George B. Massachusetts General Hospital Harvard University 'Temperature dependence of amyloid beta-protein febrilization,' 1999, Poster Session, Harvard-MIT.
17. M.A. Kamal, A.S. Alhomida, A.A. Al-Rajhi, and A.A. Al-Jafari Thermodynamic analysis of human retinal acetylcholinesterase inhibition using an anti-alzheimer drug, tacrine, through the development of a dual-substance and temperature model Proc Natl Sci Council ROC (B) 24 3 2000 108 115
18. M.A. Kamal Dual-temperature model for the estimation of energetic parameters for acetylcholinesterase inhibition by cyclophosphamide Biochem Mol Biol Int 43 1999 571 581
19. S.C. Hale, and R.A. Klone Myocardial temperature in acute myocardial infarction: protection with mild regional hypothermia Am J Physiol 273 1997 1122 1127
20. G.L. Chien, R.A. Wolff, R.F. Davis, and D.M. Van Winkle Normothermic range temperature effects myocardial infarct size Cardiovasc RE 28 1994 1014 1017
21. M.W. Dae, D.W. Gao, D. Sessler, K. Chair, and C.A. Stillson Effect of endovascular cooling on myocardial temperature, infarct size and cardiac output in human-sized pigs Am J Physiol Heart 282 2002 81484 81491
22. S.R. Dixon, R.J. Whitbourn, M.W. Dae, E. Grube, W. Sherman, G. Schaer, S.J. Jinkens, D.S. Baim, R.J. Gibbons, R.E. Kuntz, J.J. Popma, T.T. Nguyen, and W.W. O'Neill Induction of mild systemic hypothermia with endovascular cooling during primary percutaneous coronary intervention for acute myocardial infarction J Am Coll Cardiol 40 11 2002
23. L.P. Kammersgaard Low body temperature improves long-term stroke survival J Am Heart Assoc 33 2002 1759 1762
24. O. Iwata, S. Iwata, N.T. Tamuram, O.Y. Suguiam, and S. Takashima Early brain cooling in new born piglets is neuroprotective even in the absence of profound systemic hypothermia Pediatr Int 45 5 2003 522 529
25. M. De Georgia Endovascular cooling improves post-stroke mortality Neurology Aug 2004
26. D. Gendrel, J. Raymond, J. Coste, F. Moulin, M. Lorrot, S. Guerin, S. Ravilly, H. Lefevre, C. Royer, C. Lacombe, P. Palmer, and C. Bohuon Comparison of procalcitonin with C-reactive protein, interleukin-6 and interferon-alpha for differentiation of bacterial versus viral infections Pediatr Infect Disease J 18 10 1999 875 881
27. NASA/MS Study Group A randomized controlled study and chronic effects of cooling therapy for MS Neurology 60 12 2003 1955 1960
28. E. Baum, and K. Bruck Adaptive modifications in the thermo-regulatory system of long-distance runners J Appl Physiol 403 1976 404 410
29. J. Kollias, and R. Boileau Effects of physical conditioning in man on thermal responses to cold air Int J Biometeor 16 1972 389 402
30. P.L. Parmegiani, and C. Rabini Sleep and environmental temperature Arch Ital Biol 108 1970 369 387
31. T.A. Wehr A brain-warming function for REM sleep Neurosci Biobehav Rev 16 1992 379 397