Impact of the diagnosis definition on linkage detection

BMC Genetics

Volumn 6, Issue SUPPL.1, 2005, Pages

  Dizier, Marie Hélène ^a   Génin, Emmanuelle ^a   Babron, Marie Claude ^a   Bourgain, Catherine ^a  

^a HÔPITAL PAUL BROUSSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 1; CHROMOSOME 3; CHROMOSOME 9; CONTROLLED STUDY; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC TRAIT; HEREDITY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; PERSONALITY DISORDER; GENETIC DATABASE; GENETIC MARKER; GENETICS; POPULATION GENETICS; STATISTICAL MODEL;

CHROMOSOMES, HUMAN, PAIR 1; DATABASES, GENETIC; GENETIC HETEROGENEITY; GENETIC MARKERS; GENETICS, POPULATION; HUMANS; LIKELIHOOD FUNCTIONS; LINKAGE (GENETICS); PERSONALITY DISORDERS;

EID: 30344432567     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-6-S1-S140     Document Type: Article

References (7)

1. Babron M-C, Bourgain C, Leutenegger A-L, Clerget-Darpoux F: Detection of susceptibility loci by genome-wide linkage analysis. BMC Genet 2005, 6(Suppl I):S18.
2. Kruglyak L, Daly MJ, Reeve-Davy MP, Lander ES: Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 1996, 58:1347-1363.
3. Dizier MH, Quesneville H, Prum B, Selinger-Leneman H, Clerget-Darpoux F: The triangle test statistic (TTS): A test of genetic homogeneity using the departure from the triangle constraints in IBD distribution among affected sib-pairs. Ann Hum Genet 2000, 64:433-442.
4. Morton NE: The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type. Am J Hum Genet 1956, 8:80-96.
5. Risch N: Linkage strategies for genetically complex traits III. The effect of marker polymorphism on analysis of affected relative pairs. Am J Hum Genet 1990, 46:242-253.
6. Holmans P: Asymptotic properties of affected sib-pair linkage analysis. Am J Hum Genet 1993, 52:362-374.
7. Dizier MH, Besse-Schmittler C, Guilloud-Bataille M, Selinger-Leneman H, Kauffmann F, Clerget-Darpoux F, Demenais F, Epidemiological Study on the Genetics and Environment of Asthma Group: Asthma according to age at onset on chromosome 7q in 107 French EGEA families. Eur J Hum Genet 2001, 9:867-872.