The triangle test statistic (TTS): A test of genetic homogeneity using departure from the triangle constraints in IBD distribution among affected sib-pairs

Annals of Human Genetics

Volumn 64, Issue 5, 2000, Pages 433-442

  Dizier, M H ^a   Quesneville, H ^a   Prum, B ^b   Selinger Leneman, H ^a   Clerget Darpoux, F ^a  

^a INSERM   (France)

^b UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; ENVIRONMENTAL FACTOR; GENETIC HETEROGENEITY; GENETIC LINKAGE; HUMAN; PENETRANCE; PRIORITY JOURNAL; SIBLING; STATISTICAL ANALYSIS; TECHNIQUE;

ALLELES; GENETIC HETEROGENEITY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENOTYPE; HUMANS; LIKELIHOOD FUNCTIONS; LINKAGE (GENETICS); LOD SCORE; MODELS, GENETIC; MODELS, STATISTICAL; NUCLEAR FAMILY; PHENOTYPE; POLYMORPHISM, GENETIC; VARIATION (GENETICS);

EID: 0034527620     PISSN: 00034800     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0003480000008319     Document Type: Article

References (9)

1. Two-locus maximum lod score analysis of a multifactorial trait: Joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes
2. Triangle constraints for sb-pair identity by descent probabilities under general multilocus model for disease susceptibility
3. Asymptotic properties of affected-sib-pair linkage analysis
4. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
5. The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type
6. Departure from the triangle constraints in discordant sib-pairs: A test for genetic heterogeneity
7. Linkage strategies for genetically complex traits. II. The power of affected relative pairs
8. The affected sib pair IBD distribution for HLA-linked disease susceptibility genes
9. Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under non-standard conditions