The potent role of graft-derived NKR- P1+TCRαβ+ T (NKT) cells in the spontaneous acceptance of rat liver allografts

Transplantation

Volumn 80, Issue 12, 2005, Pages 1749-1755

  Kiyomoto, Tetsuma ^a   Ito, Toshinori ^a   Uchikoshi, Fumihiro ^a   Ohkawa, Atsushi ^a   Akamaru, Yusuke ^a   Miao, Gang ^a   Komoda, Hiroshi ^a   Nishida, Toshiro ^a   Matsuda, Hikaru ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

IL 10; NKR P1+TCR +t (NKT) cells; Passenger leukocytes; Rat orthotopic liver transplantation

Indexed keywords

CD161 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN; INTERLEUKIN 10; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSFORMING GROWTH FACTOR BETA;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY; IMMUNOCHEMISTRY; IRRADIATION; LIVER GRAFT; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; LYMPHOCYTE FUNCTION; MALE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RADIATION EXPOSURE; RAT; RECIPIENT; REGULATORY T LYMPHOCYTE; SPLEEN CELL; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIGENS, SURFACE; CYTOKINES; FLOW CYTOMETRY; GRAFT REJECTION; GRAFT SURVIVAL; LECTINS, C-TYPE; LIVER TRANSPLANTATION; MALE; MODELS, ANIMAL; RATS; RATS, INBRED BN; RATS, INBRED LEW; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SPLEEN; T-LYMPHOCYTES; TRANSPLANTATION, HOMOLOGOUS; WHOLE-BODY IRRADIATION;

EID: 30144444607     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000185306.40150.28     Document Type: Article

References (32)

1. Engemann R, Ulrichs K, Thiede A, et al. Value of a physiological liver transplant model in rats. Induction of specific graft tolerance in a fully allogeneic strain combination. Transplantation 1982; 33 (5): 566.
2. Houssin D, Gigou M, Franco D, et al. Specific transplantation tolerance induced by spontaneously tolerated liver allograft in inbred strains of rats. Transplantation 1980; 29 (5): 418.
3. Kamada N, Davies HS, Wight D, et al. Liver transplantation in the rat. Biochemical and histological evidence of complete tolerance induction in non-rejector strains. Transplantation 1983; 35 (4): 304.
4. Kamada N, Davies HS, Roser B. Reversal of transplantation immunity by liver grafting. Nature 1981; 292 (5826): 840.
5. Sumimoto R, Kamada N. Specific suppression of allograft rejection by soluble class I antigen and complexes with monoclonal antibody. Transplantation 1990; 50 (4): 678.
6. Kamada N. The immunology of experimental liver transplantation in the rat. Immunology 1985; 55 (3): 369.
7. Lord R, Kamada N, Kobayashi E, et al. Isolation of a 40 kDa immunoinhibitory protein induced by rat liver transplantation. Transpl Immunol 1995; 3 (2): 174.
8. Demetris AJ, Murase N, Fujisaki S, et al. Hematolymphoid cell trafficking, microchimerism, and GVH reactions after liver, bone marrow, and heart transplantation. Transplant Proc 1993; 25 (6): 3337.
9. Thomson AW, Lu L, Wan Y, et al. Identification of donor-derived dendritic cell progenitors in bone marrow of spontaneously tolerant liver allograft recipients. Transplantation 1995; 60 (12): 1555.
10. Kamada N, Shinomiya T. Clonal deletion as the mechanism of abrogation of immunological memory following liver grafting in rats. Immunology 1985; 55 (1): 85.
11. Lechler RI, Batchelor JR. Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells. J Exp Med 1982; 155 (1): 31.
12. McKenzie JL, Beard ME, Hart DN. The effect of donor pretreatment on interstitial dendritic cell content and rat cardiac allograft survival. Transplantation 1984; 38 (4): 371.
13. Sun J, Sheil AG, Wang C, et al. Tolerance to rat liver allografts: IV. Acceptance depends on the quantity of donor tissue and on donor leukocytes. Transplantation 1996; 62 (12): 1725.
14. Shimizu Y, Goto S, Lord R, et al. Restoration of tolerance to rat hepatic allografts by spleen-derived passenger leukocytes. Transpl Int 1996; 9 (6): 593.
15. Chiba S, Goto S, Shimizu Y, et al. The characterization of reconstituted passenger leukocytes on the induction of tolerance in rat liver transplantation. Transpl Int 1997; 10 (5): 350.
16. Ko S, Deiwick A, lager MD, et al. The functional relevance of passenger leukocytes and microchimerism for heart allograft acceptance in the rat. Nat Med 1999; 5 (11): 1292.
17. Arase H, Arase N, Nakagawa K, et al. NK1.1+ CD4+ CD8- thymocytes with specific lymphokine secretion. Eur J Immunol 1993; 23 (1): 307.
18. Tori M, Ito T, Kitagawa-Sakakida S, et al. Importance of donor-derived lymphocytes in the protection of pancreaticoduodenal or islet grafts from recurrent autoimmunity: a role for RT6+NKR-P1+ T cells. Transplantation 2000; 70 (1): 32.
19. Ohteki T, Okuyama R, Seki S, et al. Age-dependent increase of extrathymic T cells in the liver and their appearance in the periphery of older mice. J Immunol 1992; 149 (5): 1562.
20. Kamada N, Calne RY. A surgical experience with five hundred thirty liver transplants in the rat. Surgery 1983;93 (1 Pt 1):64.
21. Agus DB, Surh CD, Sprent J. Reentry of T cells to the adult thymus is restricted to activated T cells. J Exp Med 1991; 173 (5): 1039.
22. Goossens PL, Jouin H, Marchal G, Milon G. Isolation and flow cytometric analysis of the free lymphomyeloid cells present in murine liver. J Immunol Methods 1990; 132 (1): 137.
23. Starzl TE, Demetris AJ, Murase N, et al. The lost chord: microchimerism and allograft survival. Immunol Today 1996; 17 (12): 577.
24. Cui J, Watanabe N, Kawano T, et al. Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Valpha14 natural killer T cells. J Exp Med 1999; 190 (6): 783.
25. Yoshimoto T, Paul WE. CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J Exp Med 1994; 179 (4): 1285.
26. Sonoda KH, Faunce DE, Taniguchi M, et al. NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance. J Immunol 2001; 166 (1): 42.
27. Terabe M, Matsui S, Park JM, et al. Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J Exp Med 2003; 198 (11): 1741.
28. Tamada K, Harada M, Abe K, et al. Immunosuppressive activity of cloned natural killer (NK1.1+) T cells established from murine tumor-infiltrating lymphocytes. J Immunol 1997; 158 (10): 4846.
29. Uchikoshi F, Ito T, Kamiike W, et al. Restoration of immune abnormalities in diabetic BB rats after pancreas transplantation. I. Macrochimerism of donor-graft-derived RT6+ T cells responsible for restoration of immune responsiveness and suppression of autoimmune reaction. Transplantation 1996; 61 (11): 1629.
30. Ito T, Uchikoshi F, Tori M, et al. Immunological characteristics of pancreas transplantation: review and our experimental experience. Pancreas 2003; 27 (1): 31.
31. Ikehara Y, Yasunami Y, Kodama S, et al. CD4(+) Valpha14 natural killer T cells are essential for acceptance of rat islet xenografts in mice. J Clin Invest 2000; 105 (12): 1761.
32. Murase N, Starzl TE, Tanabe M, et al. Variable chimerism, graft-versus-host disease, and tolerance after different kinds of cell and whole organ transplantation from Lewis to brown Norway rats. Transplantation 1995; 60 (2): 158.