Approach to novel functional foods for stress control 4. Regulation of serotonin transporter by food factors

Journal of Medical Investigation

Volumn 52, Issue SUPPL., 2005, Pages 245-248

  Ito, Mikiko ^a   Haito, Sakiko ^a   Furumoto, Mari ^a   Kawai, Yoshichika ^a   Terao, Junji ^a   Miyamoto, Ken Ichi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Osteoclast; Serotonin; Serotonin transporter; SSRI; St John's wort

Indexed keywords

AMENTOFLAVONE; ANALGESIC AGENT; ANTIHISTAMINIC AGENT; HERBACEOUS AGENT; HYPERFORIN; HYPERICIN; HYPERICUM PERFORATUM EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN KINASE C; SEROTONIN; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; FUNCTIONAL FOOD; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; OSTEOCLAST; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROTONIN RELEASE; SEROTONIN UPTAKE; STRESS;

ANIMALS; BICYCLO COMPOUNDS; BIFLAVONOIDS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELLS, CULTURED; FLUOXETINE; FLUVOXAMINE; FOOD; HYPERICUM; LIGANDS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; OSTEOCLASTS; PERYLENE; PHLOROGLUCINOL; PLANT EXTRACTS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RECOMBINANT PROTEINS; SEROTONIN; STRESS; TERPENES; TIME FACTORS;

ANIMALIA; HYPERICUM; HYPERICUM PERFORATUM;

EID: 30144437256     PISSN: 13431420     EISSN: None     Source Type: Journal    
DOI: 10.2152/jmi.52.245     Document Type: Conference Paper

References (11)

1. Teitelbaum SL, Ross FP: Genetic regulation of osteoclast development and function. Nat Rev Genet 4: 638-649, 2003
2. Roodman GD: Mechanisms of bone metastasis. N Engl J Med 350: 1655-1664, 2004
3. Bekker PJ, Gay CV: Biochemical characterization of an electrogenic vacuolar proton pump in purified chicken osteoclast plasma membrane vesicles. J Bone Min Res 5: 569-579, 1990
4. Hsu H, Lacey DL, Dunstan CR, Solovyev I, Colombero A, Timms E, Tan HL, Elliott G, Kelley MJ, Sarosi I, Wang L, Xia XZ, Elliott R, Chiu L, Black T, Scully S, Capparelli C, Morony S, Shimamoto G, Bass MB, Boyle WJ: Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci USA 96: 3540-3545, 1999
5. Gershon MD: Review article: serotonin receptors and transporters-roles in normal and abnormal gastrointestinal motility. Aliment Pharmacol Ther 20 (Suppl 7): 3-14, 2004
6. Hirano K, Kato Y, Uchida S, Sugimoto Y, Yamada J, Umegaki K, Yamada S: Effects of oral administration of extracts of Hypericum perforatum (St John's wort) on brain serotonin transporter, serotonin uptake and behaviour in mice. J Pharm Pharmacol 56: 1589-1595, 2004
7. Daws LC, Toney GM, Gerhardt GA, Frazer A: In vivo chronoamperometric measures of extracellular serotonin clearance in rat dorsal hippocampus: contribution of serotonin and norepinephrine transporters. J Pharmacol Exp Ther 286: 967-976, 1998
8. Kramer HK, Poblete JC, Azmitia EC: Characterization of the translocation of protein kinase C (PKC) by 3, 4-methylenedioxymethamphetamine (MDMA/ecstasy) in synaptosomes: evidence for a presynaptic localization involving the serotonin transporter (SERT). Neuropsychopharmacology 19: 265-277, 1998
9. Ito M, Matsuka N, Izuka M, Haito S, Sakai Y, Nakamura R, Segawa H, Kuwahata M, Yamamoto H, Pike WJ, Miyamoto K: Characterization of inorganic phosphate transport in osteoclast-like cells. Am J Physiol Cell Physiol 288: C 921-C 931, 2005
10. Battaglino R, Fu J, Spate U, Ersoy U, Joe M, Sedaghat L, Stashenko P: Serotonin regulates osteoclast differentiation through its transporter. J Bone Miner Res 19: 1420-1431, 2004
11. Barker EL, Moore KR, Rakhshan F, Blakely RD: Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter. J Neurosci 19: 4705-4717, 1999