메뉴 건너뛰기




Volumn 15, Issue 4, 2005, Pages 347-370

At the edge of humanity: Human stem cells, chimeras, and moral status

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL APPROACH; ANIMAL; ANIMAL EXPERIMENT; ANIMAL WELFARE; BIOMEDICAL AND BEHAVIORAL RESEARCH; CHIMERA; COGNITION; DISEASE MODEL; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO RESEARCH; ETHICS; FETUS; GENETICS AND REPRODUCTION; HUMAN; MEDICAL TECHNOLOGY; MORALITY; PHILOSOPHICAL APPROACH; PLURIPOTENT STEM CELL; PRACTICE GUIDELINE; RESEARCH SUBJECT; REVIEW; SPECIES DIFFERENCE; STANDARD; STEM CELL TRANSPLANTATION; TRANSGENIC ANIMAL; XENOGRAFT;

EID: 30144434592     PISSN: 10546863     EISSN: None     Source Type: Journal    
DOI: 10.1353/ken.2005.0030     Document Type: Review
Times cited : (82)

References (53)
  • 3
    • 0032978190 scopus 로고    scopus 로고
    • Building Brains: Neural Chimeras in the Study of Nervous System Development and Repair
    • Brüstle, Oliver. 1999. Building Brains: Neural Chimeras in the Study of Nervous System Development and Repair. Brain Pathology 9: 527-45.
    • (1999) Brain Pathology , vol.9 , pp. 527-545
    • Brüstle, O.1
  • 4
    • 0030726664 scopus 로고    scopus 로고
    • Transplantation of Chondrocytes Utilizing Polymer-Cell Construct to Produce Tissue-Engineered Cartilage in the Shape of a Human Ear
    • Cao, Yilin; Vacanti, Joseph P.; Paige, Keith T.; et al. 1997. Transplantation of Chondrocytes Utilizing Polymer-Cell Construct to Produce Tissue-Engineered Cartilage in the Shape of a Human Ear. Plastic and Reconstructive Surgery 100: 297-302.
    • (1997) Plastic and Reconstructive Surgery , vol.100 , pp. 297-302
    • Cao, Y.1    Vacanti, J.P.2    Paige, K.T.3
  • 5
    • 0022068651 scopus 로고
    • Early Egg Production in Genetically Blind (rc/rc) Chickens in Comparison with Sighted (RC+/rc) Controls
    • Cheng, Kimberly M., and Ali, Ahmed. 1985. Early Egg Production in Genetically Blind (rc/rc) Chickens in Comparison with Sighted (RC+/rc) Controls. Poultry Science 65: 789-94.
    • (1985) Poultry Science , vol.65 , pp. 789-794
    • Cheng, K.M.1    Ali, A.2
  • 6
    • 0019075153 scopus 로고
    • An Autosomal Recessive Blind Mutant in the Chicken
    • Cheng, K. M.; Shoffner, R. N.; Gelatt, K. N.; et al. 1980. An Autosomal Recessive Blind Mutant in the Chicken. Poultry Science 59: 2179-82.
    • (1980) Poultry Science , vol.59 , pp. 2179-2182
    • Cheng, K.M.1    Shoffner, R.N.2    Gelatt, K.N.3
  • 8
    • 3142732972 scopus 로고    scopus 로고
    • Intervention, Humility and Animal Integrity
    • ed. Alan Holland and Andrew Johnson, London: Chapman and Hall
    • Cooper, David. 1998. Intervention, Humility and Animal Integrity. In Animal Biotechnology and Ethics, ed. Alan Holland and Andrew Johnson, pp. 145-55. London: Chapman and Hall.
    • (1998) Animal Biotechnology and Ethics , pp. 145-155
    • Cooper, D.1
  • 10
    • 0005600115 scopus 로고
    • Ithaca, NY: Cornell University Press
    • Devine, Philip. 1978. The Ethics of Homicide. Ithaca, NY: Cornell University Press.
    • (1978) The Ethics of Homicide
    • Devine, P.1
  • 11
    • 0037153182 scopus 로고    scopus 로고
    • Biologists Divided over Proposal to Create Human-Mouse Embryos
    • DeWitt, Natalie. 2002. Biologists Divided Over Proposal to Create Human-Mouse Embryos. Nature 420: 255.
    • (2002) Nature , vol.420 , pp. 255
    • DeWitt, N.1
  • 12
    • 4444294911 scopus 로고    scopus 로고
    • Animal Welfare Issues in the Poultry Industry: Is There a Lesson to Be Learned?
    • Duncan, Ian. 2001. Animal Welfare Issues in the Poultry Industry: Is There a Lesson to Be Learned? Journal of Applied Animal Welfare Science 4: 207-21.
    • (2001) Journal of Applied Animal Welfare Science , vol.4 , pp. 207-221
    • Duncan, I.1
  • 13
    • 0001111712 scopus 로고
    • Abortion
    • ed. Tom Regan, New York: Random House
    • Feinberg, Joel. 1980. Abortion. In Matters of Life and Death, 2d ed., ed. Tom Regan, pp. 256-93. New York: Random House.
    • (1980) Matters of Life and Death, 2d Ed. , pp. 256-293
    • Feinberg, J.1
  • 14
    • 0033215518 scopus 로고    scopus 로고
    • In Utero Hematopoietic Stem Cell Transplantation: Ontogenic Opportunities and Biologic Barriers
    • Flake, Alan, and Zanjani, Esmail. 1999. In Utero Hematopoietic Stem Cell Transplantation: Ontogenic Opportunities and Biologic Barriers. Blood 94: 2179-91.
    • (1999) Blood , vol.94 , pp. 2179-2191
    • Flake, A.1    Zanjani, E.2
  • 15
    • 30144437709 scopus 로고
    • "Animal Liberation": A Critique
    • Fox, Michael. 1978. "Animal Liberation": A Critique. Ethics 88: 106-18.
    • (1978) Ethics , vol.88 , pp. 106-118
    • Fox, M.1
  • 17
    • 30144432456 scopus 로고    scopus 로고
    • Beyond Welfare: Animal Integrity, Animal Dignity, and Genetic Engineering
    • Gavrell Ortiz, Sara. 2004. Beyond Welfare: Animal Integrity, Animal Dignity, and Genetic Engineering. Ethics and the Environment 9 (1): 94-120.
    • (2004) Ethics and the Environment , vol.9 , Issue.1 , pp. 94-120
    • Gavrell Ortiz, S.1
  • 18
    • 0003169007 scopus 로고    scopus 로고
    • Research with Human Embryonic Stem Cells: Ethical Considerations
    • Geron Ethics Advisory Board. 1999. Research with Human Embryonic Stem Cells: Ethical Considerations. Hastings Center Report 29 (2): 30-36.
    • (1999) Hastings Center Report , vol.29 , Issue.2 , pp. 30-36
  • 19
    • 0036729473 scopus 로고    scopus 로고
    • Integration and Differentiation of Human Embryonic Stem Cells Transplanted to the Chick Embryo
    • Goldstein, Ronald S.; Drukker, Micha; Reubinoff, Benjamin E.; and Nissam Benvenisty. 2002. Integration and Differentiation of Human Embryonic Stem Cells Transplanted to the Chick Embryo. Development Dynamics 225: 80-86.
    • (2002) Development Dynamics , vol.225 , pp. 80-86
    • Goldstein, R.S.1    Drukker, M.2    Reubinoff, B.E.3    Nissam, B.4
  • 21
    • 1942422687 scopus 로고    scopus 로고
    • Is It Ethical to Transplant Human Stem Cells into Nonhuman Embryos
    • Karpowicz, Phillip; Cohen, Cynthia; and van der Kooy, Derek. 2004. Is It Ethical to Transplant Human Stem Cells into Nonhuman Embryos. Nature Medicine 10: 331-35.
    • (2004) Nature Medicine , vol.10 , pp. 331-335
    • Karpowicz, P.1    Cohen, C.2    Van Der Kooy, D.3
  • 22
    • 23744506082 scopus 로고    scopus 로고
    • Developing Human-Nonhuman Chimeras in Human Stem Cell Research: Ethical Issues and Boundaries
    • _. 2005. Developing Human-Nonhuman Chimeras in Human Stem Cell Research: Ethical Issues and Boundaries. Kennedy Institute of Ethics Journal 15: 107-34.
    • (2005) Kennedy Institute of Ethics Journal , vol.15 , pp. 107-134
  • 23
    • 30144437770 scopus 로고    scopus 로고
    • Scientists Put a Bit of Man into a Mouse
    • Krieger, Lisa. 2002. Scientists Put a Bit of Man into a Mouse. Mercury News. Available at http://www.mercurynews.com/mld/mercurynews/4698610.htm. Accessed 24 August 2004.
    • (2002) Mercury News
    • Krieger, L.1
  • 24
    • 0004247732 scopus 로고
    • ed. George Sher. Indianapolis: Hackett Publishing Company
    • Mill, John Stuart. 1979 [1861]. Utilitarianism, ed. George Sher. Indianapolis: Hackett Publishing Company.
    • (1861) Utilitarianism
    • Mill, J.S.1
  • 25
    • 0035016560 scopus 로고    scopus 로고
    • Chimeras and Mosaics for Dissecting Complex Mutant Phenotypes
    • Nagy, Andras, and Rossant, Janet. 2001. Chimeras and Mosaics for Dissecting Complex Mutant Phenotypes. International Journal of Developmental Biology 45: 577-82.
    • (2001) International Journal of Developmental Biology , vol.45 , pp. 577-582
    • Nagy, A.1    Rossant, J.2
  • 26
    • 30144441999 scopus 로고    scopus 로고
    • 12-13 October. Washington, DC
    • NAS. National Academy of Sciences. Committee on Guidelines for Human Embryonic Stem Cell Research. 2004. Workshop on Guidelines for Human Embryonic Stem Cell Research, 12-13 October. Washington, DC.
    • (2004) Workshop on Guidelines for Human Embryonic Stem Cell Research
  • 30
    • 30144435211 scopus 로고    scopus 로고
    • Human Embryonic Stem Cells: A Primer on the Technology and Its Medical Applications
    • ed. Suzanne Holland, Karen Lebacqz, and Laurie Zoloth, Cambridge, MA: MIT Press
    • Okarma, Thomas. 2001. Human Embryonic Stem Cells: A Primer on the Technology and Its Medical Applications. In The Human Embryonic Stem Cell Debate, ed. Suzanne Holland, Karen Lebacqz, and Laurie Zoloth, pp. 3-13. Cambridge, MA: MIT Press.
    • (2001) The Human Embryonic Stem Cell Debate , pp. 3-13
    • Okarma, T.1
  • 32
    • 30144438624 scopus 로고
    • Fox's Critique of Animal Liberation
    • Regan, Tom. 1978. Fox's Critique of Animal Liberation. Ethics 88: 126-33.
    • (1978) Ethics , vol.88 , pp. 126-133
    • Regan, T.1
  • 34
    • 0002550429 scopus 로고    scopus 로고
    • On Telos and Genetic Engineering
    • ed. Alan Holland and Andrew Johnson, London: Chapman and Hall
    • Rollin, Bernard E. 1998. On Telos and Genetic Engineering. In Animal Biotechnology and Ethics, ed. Alan Holland and Andrew Johnson, pp. 156-71. London: Chapman and Hall.
    • (1998) Animal Biotechnology and Ethics , pp. 156-171
    • Rollin, B.E.1
  • 36
    • 30144440171 scopus 로고    scopus 로고
    • The Other Stem-Cell Debate
    • 10 April
    • Shreeve, Jamie. 2005. The Other Stem-Cell Debate. New York Times Magazine (10 April): 42-47.
    • (2005) New York Times Magazine , pp. 42-47
    • Shreeve, J.1
  • 37
    • 30144438993 scopus 로고
    • An Inherited Delayed Amelanosis with Associated Blindness in the Domestic Fowl
    • Smyth, J. R., Jr.; Boissey, R. E.; Gawron, M. F. 1977. An Inherited Delayed Amelanosis with Associated Blindness in the Domestic Fowl. Poultry Science 56: 1758.
    • (1977) Poultry Science , vol.56 , pp. 1758
    • Smyth Jr., J.R.1    Boissey, R.E.2    Gawron, M.F.3
  • 38
    • 85012457748 scopus 로고    scopus 로고
    • In Defense of the Moral Relevance of Species Boundaries
    • Streiffer, Robert. 2003. In Defense of the Moral Relevance of Species Boundaries. American Journal of Bioethics 3 (3): 37-38.
    • (2003) American Journal of Bioethics , vol.3 , Issue.3 , pp. 37-38
    • Streiffer, R.1
  • 39
    • 22844449291 scopus 로고    scopus 로고
    • The Political Import of Intrinsic Objections to Genetically Engineered Food
    • _, and Thomas Hedemann. 2005. The Political Import of Intrinsic Objections to Genetically Engineered Food. Journal of Agricultural and Environmental Ethics 18: 191-210.
    • (2005) Journal of Agricultural and Environmental Ethics , vol.18 , pp. 191-210
    • Hedemann, T.1
  • 40
    • 30144432064 scopus 로고    scopus 로고
    • Stem Cells
    • ed. Justine Burley and John Harris, Malden, MA: Blackwell Publishing Ltd.
    • Svendsen, Clive. 2002. Stem Cells. In A Companion to Genethics, ed. Justine Burley and John Harris, pp. 7-17. Malden, MA: Blackwell Publishing Ltd.
    • (2002) A Companion to Genethics , pp. 7-17
    • Svendsen, C.1
  • 41
    • 0033517366 scopus 로고    scopus 로고
    • Genetic Enhancement of Learning and Memory in Mice
    • Tang, Ya-Ping; Shimizu, Eiji; Dube, Gilles Ru.; et al. 1999. Genetic Enhancement of Learning and Memory in Mice. Nature 401: 63-69.
    • (1999) Nature , vol.401 , pp. 63-69
    • Tang, Y.-P.1    Shimizu, E.2    Dube, G.Ru.3
  • 43
    • 30144435211 scopus 로고    scopus 로고
    • Human Embryonic Stem Cells
    • ed. Suzanne Holland, Karen Lebacqz, and Laurie Zoloth, Cambridge, MA: MIT Press
    • Thomson, James. 2001. Human Embryonic Stem Cells. In The Human Embryonic Stem Cell Debate, ed. Suzanne Holland, Karen Lebacqz, and Laurie Zoloth, pp. 14-26. Cambridge, MA: MIT Press.
    • (2001) The Human Embryonic Stem Cell Debate , pp. 14-26
    • Thomson, J.1
  • 44
    • 30144439938 scopus 로고
    • Ruminations on an Account of Personal Identity
    • ed. Judith Jarvis Thomson, Cambridge, MA: MIT Press
    • Thomson, Judith Jarvis. 1987. Ruminations on an Account of Personal Identity. In On Being and Saying: Essays for Richard Cartwright, ed. Judith Jarvis Thomson, pp. 215-40. Cambridge, MA: MIT Press.
    • (1987) On Being and Saying: Essays for Richard Cartwright , pp. 215-240
    • Thomson, J.J.1
  • 45
    • 23644435656 scopus 로고    scopus 로고
    • People and their Bodies
    • ed. Jonathan Dancy, Oxford: Blackwell Publishers
    • _. 1997. People and their Bodies. In Reading Parfit, ed. Jonathan Dancy, pp. 202-29. Oxford: Blackwell Publishers.
    • (1997) Reading Parfit , pp. 202-229
  • 48
    • 84947851566 scopus 로고
    • Interspecific Justice
    • VanDeVeer, Donald. 1979. Interspecific Justice. Inquiry 22: 55-70.
    • (1979) Inquiry , vol.22 , pp. 55-70
    • VanDeVeer, D.1
  • 49
    • 0037183884 scopus 로고    scopus 로고
    • Little Evidence of Developmental Plasticity of Adult Hematopoietic Stem Cells
    • Wagers, Amy; Sherwood, Richard; Christensen, Julie, and Weissman, Irving. 2002. Little Evidence of Developmental Plasticity of Adult Hematopoietic Stem Cells. Science 297: 2256-59.
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.1    Sherwood, R.2    Christensen, J.3    Weissman, I.4
  • 50
    • 16644388209 scopus 로고    scopus 로고
    • Of Mice, Men and In-Between: Scientists Debate Blending of Human, Animal Forms
    • 20 November
    • Weiss, Rick. 2004. Of Mice, Men and In-Between: Scientists Debate Blending of Human, Animal Forms. Washington Post (20 November): A01.
    • (2004) Washington Post
    • Weiss, R.1
  • 51
    • 0004118270 scopus 로고    scopus 로고
    • Princeton, NJ: Princeton University Press
    • Wertheimer, Alan. 1996. Exploitation. Princeton, NJ: Princeton University Press.
    • (1996) Exploitation
    • Wertheimer, A.1
  • 52
    • 33644497182 scopus 로고    scopus 로고
    • WiCell. 2001. Memorandum of Understanding. Available at http://www.news.wisc.edu/story.php?get=6457. Accessed 25 October 2005.
    • (2001) Memorandum of Understanding
  • 53
    • 0035200623 scopus 로고    scopus 로고
    • In Vitro Differentiation of Transplantable Neural Precursors from Human Embryonic Stem Cells
    • Zhang, Su-Chun; Wernig, Marius; Duncan, Ian; et al. 2001. In Vitro Differentiation of Transplantable Neural Precursors from Human Embryonic Stem Cells. Nature Biotechnology 19: 1129-33.
    • (2001) Nature Biotechnology , vol.19 , pp. 1129-1133
    • Zhang, S.-C.1    Wernig, M.2    Duncan, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.