Calcineurin localization in skeletal muscle offers insights into potential new targets

Journal of Histochemistry and Cytochemistry

Volumn 54, Issue 1, 2006, Pages 119-128

  Torgan, Carol E ^a   Daniels, Mathew P ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Calcineurin; Myoblast; Nucleolus; Nucleus; Ryanodine receptor; Skeletal muscle; Triad

Indexed keywords

CALCINEURIN; CALCIUM CALMODULIN ACTIVATED PROTEIN PHOSPHATASE; CALMODULIN DERIVATIVE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE (CALCIUM,CALMODULIN); UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CELL STRAIN COS7; CELLULAR DISTRIBUTION; CLINICAL PATHWAY; COMPLEX FORMATION; CONTROLLED STUDY; FETUS; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOREACTIVITY; MUSCLE DEVELOPMENT; MUSCLE FIBRIL; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RAT; SARCOPLASMIC RETICULUM; SENSITIVITY AND SPECIFICITY; SKELETAL MUSCLE;

ANIMALS; CALCINEURIN; CELL NUCLEOLUS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CYTOPLASM; MICE; MUSCLE FIBERS; MUSCLE, SKELETAL; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

ANIMALIA;

EID: 30044447811     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.5A6769.2005     Document Type: Article

References (39)

1. Alto N, Carlisle Michel JJ, Dodge KL, Langeberg LK, Scott JD (2002) Intracellular targeting of protein kinases and phosphatases. Diabetes 51:8385-388
2. Aramburu J, Rao A, Klee CB (2000) Calcineurin: from structure to function. Curr Top Cell Regul 36:237-295
3. Arevalo-Rodriguez M, Heitman J (2005) Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyccs cerevisiae. Eukaryot Cell 4:17-29
4. 2+-release channels: regulation or association: Biochem Biophys Res Commun 311:1181-1193
5. Burkard N, Becher J, Heindl C, Neyses L, Schuli K, Ritter O (2005) Targeted proteolysis sustains calcineurin activation. Circulation 111:1045-1053
6. 2+ flux. Cell 83:463-472
7. Carmody M, Mackrill JJ, Sorrentino V, O'Neill C (2001) FKBP12 associates tightly with the skeletal muscle type 1 ryanodine receptor, but not with other intracellular calcium release channels. FEBS Lett 505:97-102
8. Delling U, Tureckova J, Lim HW, De Windt LJ, Rotwein P, Molkentin JD (2000) A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression. Mol Cell Biol 20:6600-6611
9. 2+ response amplitude and duration. Nature 386:855-858
10. Dundr M, Hofmann-Rohrer U, Hu Q, Grummt I, Rothblum LI, Phair RD, Misteli T (2002) A kinetic framework for a mammalian RNA polymerase in vivo. Science 298:1623-1626
11. Dundr M, Misteli T (2001) Functional architecture in the cell nucleus. Biochem J 356:297-310
12. Dutton EK, Uhm C-S, Samuelsson SJ, Schaffner AE, Fitzgerald SC, Daniels MP (1995) Acetylcholine receptor aggregation at nerve-muscle contacts in mammalian cultures: induction by ventral spinal cord neurons is specific to axons. J Neurosci 15:7401-7416
13. Echevarria W, Leite MF, Guerra MT, Zipfel WR, Nathanson MH (2003) Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum. Nat Cell Biol 5:440-446
14. Flucher BE, Andrews SB, Daniels MP (1994) Molecular organization of transverse tubule/sarcoplasmic reticulum junctions during development of excitation-contraction coupling in skeletal muscle. Mol Biol Cell 5:1105-1118
15. Forrest ARR, Ravasi T, Taylor D, Huber T, Hume DA, Grimmond S. RIKEN GER Group, GSL members (2003) Phosphoregulators: protein kinases and protein phosphatases of mouse. Genome Res 13:1443-1454
16. 2+ release units in skeletal and cardiac muscle. Ann NY Acad Sci 853:20-30
17. Frey N, Richardson JA, Olson EA (2000) Calsarcins, a novel family of sarcomeric calcineurin-binding proteins. Proc Natl Acad Sci USA 97:14632-14637
18. Friday BB, Horsley V, Pavlath GK (2000) Calcineurin activity is required for the initiation of skeletal muscle differentiation. J Cell Biol 149:657-665
19. Friday BK, Pavlath GK (2001) A calcineurin- and NFAT-dcpendent pathway regulates Myf5 gene expression in skeletal muscle reserve cells. J Cell Sci 114:303-310
20. Heincke J, Ruetten H, Willenbockel C, Gross SC, Naguib M, Schaefer A, Kempf T, et al. (2005) Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcinenrin signaling at the sarcomeric Z-disc. Proc Natl Acad Sci USA 102:1655-1660
21. 2+ signals in cultured skeletal muscle. Am J Physiol Cell Physiol 278:C998-1010
22. Leeson TS (1980) T-tubules, couplings and myofibrillar arrangements in rat atrial myocardium. Acta Anat (Basel) 108:374-388
23. 2+ signaling with the involvement of mitochondria. Biochem Biophys Res Commun 308:826-833
24. Mitchell PO, Pavlath GK (2002) Multiple roles of calcineurin in skeletal muscle growth. Clin Orthop Relat Res 403S:S197-S202
25. Musaro A, McCullagh KJA, Naya FJ, Olson EN, Rosenthal N (1999) IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Nature 400:581-585
26. Ochs RL, Lischwe MA, Spohn WH, Busch H (1985) Fibrillarin: a new protein of the nucleolus identified by autoimmune sera. Biol Cell 54:123-133
27. Olson RN, Williams RS (2000) Remodeling muscles with calcineurin. Bioessays 22:510-519
28. Pombo A, Cuello P, Schul W, Yoon J-B, Roeder RG, Cook PR, Murphy S (1998) Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle. EMBO J 17:1768-1778
29. Portoles M, Faura M, Renau-Piqueras J, Iborra FJ, Saez R, Guerri C, Serratosa J, et al. (1994) Nuclear calmodulin/62 kDa calmodulin-binding protein complexes in interphasic and mitotic cells. J Cell Sci 107:3601-3614
30. Rusnak F, Mertz P (2000) Calcineurin: form and function. Physiol Rev 80:1483-1521
31. Sacchetto R, Damiani E, Margreth A (2002) Clues to calcineurin function in mammalian fast-twitch muscle. J Muscle Res Cell Motil 22:545-559
32. 2+- dependent calcineurin signaling pathway. Nature 400:576-581
33. Shibasaki F, Price ER, Milan D, McKeon F (1996) Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4. Nature 382:370-373
34. 2+ release channel in skeletal muscle. Biophys J 83:2539-2549
35. Spector DL (2001) Nuclear domains. J Cell Sci 114:2891-2893
36. 2+ signals and immunosuppression. Nature 383:837-840
37. Torgan CE, Daniels MP (2001) Regulation of myosin heavy chain expression during rat skeletal muscle development in vitro. Mol Biol Cell 12:1499-1508
38. Wilkins BJ, Molkentin JD (2004) Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun 322:1178-1191
39. Zou Y, Yao A, Zhu W, Kudoh S, Hiroi Y, Shimoyama M, Uozumi H, et al. (2001) Isoproterenol activates extracellular signal-regulated protein kinases in cardiomyocytes through calcineurin. Circulation 104:102-108