Proteases from Lonomia obliqua venomous secretions: Comparison of procoagulant, fibrin(ogen)olytic and amidolytic activities

Toxicon

Volumn 47, Issue 1, 2006, Pages 113-121

  Pinto, Antônio F M ^a   Silva, Kátia R L M ^a   Guimarães, Jorge A ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Bleeding disorder; Coagulation; Fibrinolysis; Hemostasis; Lonomia obliqua

Indexed keywords

DIVALENT CATION; FIBRINOGEN; INSECT VENOM; PROCOAGULANT; PROTEINASE;

ARTICLE; BUTTERFLY; CONTROLLED STUDY; ELECTROPHORESIS; ENVENOMATION; FIBRINOLYSIS; HEMOLYMPH; IMMUNOHISTOCHEMISTRY; INTEGUMENT; NONHUMAN; PRIORITY JOURNAL;

AMIDOHYDROLASES; ANIMALS; ARTHROPOD VENOMS; BLOOD COAGULATION; BLOOD COAGULATION TESTS; BRAZIL; FIBRINOGEN; FIBRINOLYSIS; HEMOLYSIS; LEPIDOPTERA; PEPTIDE HYDROLASES; TIME FACTORS;

INSECTA; LONOMIA;

EID: 29944443839     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2005.10.004     Document Type: Article

References (27)

1. H.B. Abella, J.B. Torres, M.G.B. Marques, A.C. Duarte, and E. Barros Manual de Diagnóstico e Tratamento de Acidentes por Lonomia 1998 CIT (Centro de Informação Toxicológica) Porto Alegre
2. C.L. Arocha-Piñango, and M. Layrisse Fibrinolysis produced by contact with a caterpillar The Lancet 1 1969 810 812
3. C.L. Arocha-Piñango, N.B. De Bosch, A. Torres, C. Goldstein, A. Nouel, A. Argüello, Z. Carvajal, B. Guerrero, A. Ojeda, A. Rodriguez, and S. Rodriguez Six new cases of a caterpillar-induced bleeding syndrome Thrombosis and Haemostasis 67 1992 402 407
4. P. Couppié, C. Marty, D. Sainte-Marie, and R. Pradinaud Chenilles venimeuses de Guyane Française: 5 observations Annales de Dermatologie et de Vénéréologie 125 1998 489 491
5. W.D. daSilva, A.C.M.R. Campos, L.R.C. Gonçalves, M.C.C. Souza-e-Silva, H.G. Higashi, I.K. Yamagushi, and E.M.A. Kelen Development of an antivenom against toxins of Lonomia obliqua caterpillars Toxicon 34 1996 1045 1049
6. G. Datta, A. Dong, J. Witt, and A.T. Tu Biochemical characterization of Basilase, a fibrinolytic enzyme from Crotalus basiliscus basiliscus Archives of Biochemistry and Biophysics 317 1995 365 373
7. J.L. Donato, R.A. Moreno, S. Hyslop, A. Duarte, E. Antunes, B.F. Le Bonniec, F. Rendu, and G. De Nucci Lonomia obliqua caterpillar spicules trigger human blood coagulation via activation of factor X and prothrombin Thrombosis and Haemostasis 79 1998 539 542
8. A.C. Duarte, J. Caovilla, I. Lorini, D. Lorini, G. Mantovani, J. Sumida, P.C. Manfre, R.C. Silveira, and S.P. Dr Moura Insuficiência renal aguda por acidentes com lagartas Jornal Brasileiro de Nefrologia 12 4 1990 184 186
9. Fraiha Neto, H., Amaral, I.M., Ballarini, A.J., 1985. Lonomia achelous (Cramer) (Lepidoptera, Saturniidae), o 'tapuru da seringueira', agente do acidente hemorrágico por contato com larvas de mariposa no território Federal do Amapá. Resumo do XX Congresso da Sociedade Brasileira de Medicina Tropical, São Paulo, p. 24.
10. M. Fritzen, M. Schattner, A.L.Q. Ribeiro, I.F.C. Batista, J. Ventura, B.C. Prezoto, and A.M. Chudzinski-Tavassi Lonomia obliqua venom action on fibrinolytic system Thrombosis Research 112 2003 105 110
11. B.A.G. Guerrero, C.L. Arocha-Piñango, and A. Gil Lonomia achelous caterpillar venom (LACV) selectively inactivates blood clotting factor XIII Thrombosis Research 87 1997 83 93
12. B.A.G. Guerrero, C.L. Arocha-Piñango, and A. Gil Degradation of human factor XIII by Lonomin V, a purified fraction of Lonomia achelous caterpillar venom Thrombosis Research 87 1997 171 181
13. B.A.G. Guerrero, J. Perales, A. Gil, and C.L. Arocha-Piñango Effect on platelet FXIII and partial characterization of Lonomin V, a proteolytic enzyme from Lonomia achelous caterpillars Thrombosis Research 93 1999 243 252
14. C. Hougie Fundamentals of Blood Coagulation and Clinical Medicine 1963 McGraw-Hill New York pp. 25-48
15. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
16. P.K. Ngai, and J.Y. Chang A novel one-step purification of human α-thrombin after direct activation of crude prothrombin enriched from plasma Biochemical Journal 280 1991 805 808
17. Pinto, A.F.M., Veiga, A.B.G., Blochtein, B., Guimarães, J.A., 2000. Proteases from different secretions are involved on the paradoxial (pro-coagulant and hemorrhagic) envenomation caused by Lonomia obliqua caterpillars. In: Ménez, A. et al. (Org.), Toxins from Animals, Plants and Microbes. Program and Abstracts Book - XIIIth World Congress of the International Society on Toxinology-IST, Paris, p. 178.
18. A.F.M. Pinto, R. Dobrovolski, A.B.G. Veiga, and J.A. Guimarães Lonofibrae, a novel α-fibrinogenase from Lonomia obliqua caterpillars Thrombosis Research 113 2004 147 154
19. ++ activated serine protease (LOPAP) could be responsible for the haemorrhagic syndrome caused by the caterpillar Lonomia obliqua The Lancet 353 1999 1942
20. C.V. Reis, F.C.V. Portaro, S.A. Andrade, M. Fritzen, B.L. Fernandes, C.A.M. Sampaio, A.C.M. Camargo, and A.M. Chudzinski-Tavassi A prothrombin activator serine protease from the Lonomia obliqua caterpillar venom (Lopap) biochemical characterization Thrombosis Research 102 2001 427 436
21. J.M. Ribeiro, M. Schneider, and J.A. Guimarães Purification and characterization of Prolixin S (Nitrofhorin 2), the salivary anticoagulant of the blood-sucking bug Rhodnius prolixus Biochemical Journal 308 1995 243 249
22. C.S. Seibert, E.M.G. Shinohara, and I.S. Sano-Martins In vitro hemolytic activity of Lonomia obliqua caterpillar bristle extract on human and Wistar rat erythrocytes Toxicon 41 2003 831 839
23. A.B.G. Veiga, B. Blochtein, and J.A. Guimarães Structures involved in production, secretion and injection of the venom produced by the caterpillar Lonomia obliqua (Lepidoptera, Saturniidae) Toxicon 39 2001 1343 1351
24. A.B.G. Veiga, A.F.M. Pinto, and J.A. Guimarães Fibrinogenolytic and procoagulant activities in the hemorrhagic syndrome caused by Lonomia obliqua caterpillars Thrombosis Research 111 2003 95 101
25. A.B.G. Veiga, J.M. Ribeiro, J.A. Guimarães, and I.M.B. Francischeti A catalog for the transcripts from the venomous structure of the caterpillar Lonomia obliqua: identification of the proteins potentially involved in the coagulation disorder and hemorrhagic syndrome Gene 355 2005 11 27
26. R. Von Ihering Estudo biologico das lagartas urticantes ou tatoranas Annaes Paulistas de Medicina e Cirurgia 3 1914 129 139
27. M. Zannin, D.M. Lourenço, G. Motta, L.R.D. Costa, M. Grando, G.P. Gamborgi, M.A. Noguti, and A.M. Chudzinski-Tavassi Blood coagulation and fibrinolytic factors in 105 patients with hemorrhagic syndrome caused by accidental contact with Lonomia obliqua caterpillar in Santa Catarina, Southern Brazil Thrombosis and Haemostatis 89 2003 355 364