A Ca++ activated serine protease (LOPAP) could be responsible for the haemorrhagic syndrome caused by the caterpillar Lonomia obliqua

Lancet

Volumn 353, Issue 9168, 1999, Pages 1942-

  Reis, C V ^a   Kelen, E M A ^a   Farsky, S H P ^a   Portaro, F C V ^a   Sampaio, C A M ^a   Fernandes, B L ^a   Camargo, A C M ^a   Chudzinski Tavassi, A M ^a  

^a INSTITUTO BUTANTAN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

SERINE PROTEINASE; TOXIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING DISORDER; BLOOD CLOTTING; CONTROLLED STUDY; LARVA; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; TOXIN ANALYSIS;

EID: 0033526561     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(99)01777-8     Document Type: Article

References (4)

1. Killer Brazilian Caterpillars. In Daily inScight. Science 12 October, 1996.
2. Duarte AC, Crusius PS, Pires CAL, Schilling MA, Fan HW. Intracerebral hemorrhage after contact with Lonomia caterpillar. Lancet 1996; 348: 1033.
3. Kelen EMA, Picarelli ZP, Duarte AC. Hemorrhagic syndrome induced by contact with caterpillars of the genus Lonomia (Saturniidae, Hemolleucinae). J Toxicol-Toxin Ver 1995; 14: 283-308.
4. Kelen EMA, Duarte AC, Tomy SC, et al. Acquired haemorrhagic syndrome from contact with a caterpillar (Lonomia obliqua Walker 1855, Saturniidae). Toxicon 1996; 34: 146 (abstr).