Thiopurine S-methyltransferase polymorphisms and the relationship between the mutant alleles and the adverse effects in systemic lupus erythematosus patients taking azathioprine

Clinical and Experimental Rheumatology

Volumn 23, Issue 6, 2005, Pages 873-876

  Jun, Jae Bum ^a   Cho, Dae Yeon ^b   Kang, Changwon ^c   Bae, Sang Cheol ^a  

^a Hanyang University   (South Korea)

^b Doo San Engineering Center   (South Korea)

^c Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Azathioprine; Polymorphism; Systemic lupus erythematosus; Thiopurine methyltransferase

Indexed keywords

AZATHIOPRINE; MUTANT PROTEIN; THIOPURINE METHYLTRANSFERASE;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; BONE MARROW TOXICITY; CHILD; CORRELATION ANALYSIS; DISEASE SEVERITY; DRUG ERUPTION; DRUG RESPONSE; DRUG TOLERABILITY; FEMALE; GASTROINTESTINAL SYMPTOM; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOSITY; HUMAN; KOREA; LEUKOPENIA; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; NAUSEA; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADOLESCENT; ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; AZATHIOPRINE; CHILD; FEMALE; GENOTYPE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KOREA; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; METHYLTRANSFERASES; MIDDLE AGED; POLYMORPHISM, GENETIC; RETROSPECTIVE STUDIES;

EID: 29944443581     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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