NC100668, a new tracer for imaging of venous thromboembolism: Disposition and metabolism in rats

Drug Metabolism and Disposition

Volumn 34, Issue 1, 2006, Pages 111-120

  Skotland, Tore ^a,b   Hustvedt, Svein Olaf ^a   Oulie, Inger ^a   Jacobsen, Petter Balke ^a   Friisk, Grete Arneberg ^a   Langøy, Ann Svendsen ^a   Uran, Steinar ^a   Sandosham, Jessie ^a   Cuthbertson, Alan ^a   Toft, Kim Gunnar ^a  

^a GE Healthcare   (United States)

^b BIACORE AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; CARBON 14; DRUG METABOLITE; GLYCINE; LYSINE; NC 100668; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG; URANIUM;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DRUG ABSORPTION; DRUG DISPOSITION; DRUG IDENTIFICATION; DRUG METABOLISM; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; ISOTOPE LABELING; KIDNEY CORTEX; KIDNEY TUBULE ABSORPTION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM; RADIOACTIVITY; RADIOASSAY; RAT; URINALYSIS; VENOUS THROMBOEMBOLISM;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, OUTBRED STRAINS; AUTORADIOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FECES; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IMAGE ENHANCEMENT; INJECTIONS; MALE; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN BINDING; RADIOACTIVE TRACERS; RADIOPHARMACEUTICALS; RATS; THROMBOEMBOLISM; TISSUE DISTRIBUTION; VENOUS THROMBOSIS;

ANIMALIA;

EID: 29944437977     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.105.006239     Document Type: Article

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