Endotoxin-induced heart dysfunction in rats: Assessment of myocardial perfusion and permeability and the role of fluid resuscitation

Critical Care Medicine

Volumn 34, Issue 1, 2006, Pages 127-133

  Chagnon, Frederic ^a   Bentourkia, M'hamed ^a   Lecomte, Roger ^a   Lessard, Michel ^a   Lesur, Olivier ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Capillary permeability; Myocardial dysfunction; Positron emission tomography; Sepsis; Septic shock

Indexed keywords

ENDOTOXIN; LACTIC ACID; TROPONIN I;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLOID; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ESCHERICHIA COLI; EVALUATION; FLUID RESUSCITATION; HEART DISEASE; HEART MUSCLE PERFUSION; HEART OUTPUT; LABORATORY TEST; MALE; NONHUMAN; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SEPTIC SHOCK;

EID: 29744460916     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000190622.02222.DF     Document Type: Article

References (39)

1. Angus DC, Linde-Zwirble WT, Lidicker J, et al: Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29:1303-1310
2. Bernard GR, Vincent JL, Laterre PF, et al: Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709
3. Annane D, Sebille V, Charpentier C, et al: Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002; 288:862-871
4. Krishnagopalan S, Kumar A, Parrillo JE, et al: Myocardial dysfunction in the patient with sepsis. Curr Opin Crit Care 2002; 8:376-388
5. Lee K, van der Zee H, Dziuban SW Jr, et al: Cardiac function and coronary flow in chronic endotoxemic pigs. Proceedings of the Society for E.B.M. 1988; 189:245-252
6. Solomon MA, Correa R, Alexander HR, et al: Myocardial energy metabolism and morphology in a canine model of sepsis. Am J Physiol 1994; 266:H757-H768
7. Stahl TJ, Alden PB, Ring WS, et al: Sepsis-induced diastolic dysfunction in chronic canine peritonitis. Am J Physiol 1990; 258:H625-H633
8. Kumar A, Bunnell E, Lynn M, et al: Experimental human endotoxemia is associated with depression of load-independent contractility indices. Chest 2004; 126:860-867
9. Parker MM, Shelhamer JH, Bacharach SL, et al: Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med 1984; 100:483-490
10. Vincent JL, Gris P, Coffernils M, et al: Myocardial depression characterizes the fatal course of septic shock, Surgery 1992; 111:660-667
11. Cunnion RE, Schaer GL, Parker MM, et al: The coronary circulation in human septic shock. Circulation 1986; 73:637-644
12. Dhainaut JF, Huyghebaert MF, Monsallier JF, et al: Coronary hemodynamics and myocardial metabolism of lactate, free fatty acids, glucose, and ketones in patients with septic shock. Circulation 1987; 3:533-541
13. Wu AH: Increased troponin in patients with sepsis and septic shock: Myocardial necrosis or reversible myocardial depression? Intensive Care Med 2001; 27:959-961
14. Turner A, Tsamitros M, Bellomo R: Myocardial cell injury in septic shock. Crit Care Med 1999; 27:1775-1780
15. Mehta NJ, Khan IA, Gupta V, et al: Cardiac troponin I predicts myocardial dysfunction and adverse outcome in septic shock. Int J Cardiol 2004; 95:13-17
16. Raeburn CD, Calkins CM, Zimmerman MA, et al: Vascular cell adhesion molecule-1 expression is obligatory for endotoxin-induced myocardial neutrophil accumulation and contractile dysfunction. Surgery 2001; 130:319-325
17. Knuefermann P, Nemoto S, Misra A, et al: CD14-deficient mice are protected against LPS-induced cardiac inflammation and left ventricular dysfunction. Circulation 2002; 106:2608-2615
18. Favory R, Lancel S, Marchetti P, et al: Endotoxin-induced myocardial dysfunction: Evidence for a role of sphingosine production. Crit Care Med 2004; 32:495-501
19. Chagnon F, Metz CN, Bucala R, et al: Endotoxin-induced myocardial dysfunction: Effects of macrophage migration inhibitory factor (MIF) neutralization. Circ Res 2005; 96:1095-1102
20. Saito H, Patterson C, Hu Z, et al: Expression and self-regulatory function of cardiac interleukin-6 during endotoxemia. Am J Physiol 2000; 279:H2241-H2248
21. Neviere R, Fauvel H, Chopin C, et al: Caspase inhibition prevents cardiac dysfunction and heart apoptosis in a rat model of sepsis. Am J Respir Crit Care Med 2002; 165:449-455
22. Hersch M, Gnidec AA, Bersten AD, et al: Histologic and ultrastructural changes in nonpulmonary organs during early hyperdynamic sepsis. Surgery 1990; 107:397-410
23. Yu P, Boughner DR, Sibbald WJ, et al: Myocardial collagen changes and edema in rats with hyperdynamic sepsis. Crit Care Med 1997; 25:657-662
24. Marik PE, Varon J: Sepsis: State of the art. Dis Mon 2001; 47:461-532
25. Bianchi C, Araujo EG, Sato K, et al: Biochemical and structural evidence for pig myocardium adherens junction disruption by cardiopulmonary bypass. Circulation 2001, 104(Suppl 1):I319-I324
26. Camici PG, Dutka DP: Repetitive stunning, hibernation, and heart failure: Contribution of PET to establishing a link. Am J Physiol 2001; 280:H929-H936
27. Boldt J, Mueller M, Menges T, et al: Influence of different volume therapy regimens on regulators of the circulation in the critically ill. Br J Anaesth 1996; 77:480-487
28. Choi PT, Yip G, Quinonez LG, et al: Crystalloids versus colloids in fluid resuscitation: A systematic review. Crit Care Med 1999; 27:200-210
29. Canadian Council of Animal Care: Guide to the Care and Use of Experimental Animals. Second Edition. Ottawa, Ontario, Canada, Canadian Council of Animal Care, 1993
30. Sahn DJ, DeMaria A, Kisslo J, et al: Recommendations regarding quantitation in M-Mode echocardiography: Results of a survey of echocardiographic measurements. Circulation 1978; 58:1072-1083
31. Levy B, Vallee C, Lauzier F, et al: Comparative effects of vasopressin, norepinephrine and L-Canavanine, a selective inhibitor of inducible nitric oxide synthase in endotoxic shock. Am J Physiol 2004; 287:H209-H215
32. Lehr HA, Mankoff DA, Corwin D, et al: Application of photoshop-based image analysis to quantification of hormone receptor expression in breast cancer. J Histochem Cytochem 1997; 45:1559-1565
33. Bentourkia M, Croteau E, Langlois R, et al: Coupling of 11C-acetate and 13N-ammonia for measurement of myocardial blood flow in normal and ischemic rats using the Sherbrooke PET scanner. IEEE Trans Nucl Sci 2002; 49:2322-2327
34. Bertichant JP, Polge A, Juan JM, et al: Evaluation of cardiac troponin I and T levels as markers of myocardial damage in doxorubicin-induced cardiomyopathy rats, and their relationship with echocardiographic and histological findings. Clin Chim Acta 2003; 329:39-51
35. Lamontagne F, Bénard F, Lesur O. Positron emission tomography: Anticipated usefulness in critical care settings. In: Yearbook of Intensive Care and Emergency Medicine. New York, JL Vincent (Ed). 2003, pp 737-746
36. Lewis DH: The effects of multiple organ failure on the regulation of the circulation with special reference to the circulation. In: Microcirculation in Circulatory Disorders. Manabe H, Zweifach BW, Messmer K (Eds). Tokyo, Berlin, Heidelberg, Springer, 1988, pp 103-108
37. Walley KR, McDonald TE, Wang Y, et al: Albumin resuscitation increases cardiomyocyte contractility and decreases nitric oxide synthase II expression in rat endotoxemia. Crit Care Med 2003; 31:187-194
38. Boldt J, Muller M, Mentges D, et al: Volume therapy in the critically ill: Is there a difference. Intensive Care Med 1998; 24:28-36
39. Boldt J, Heesen M, Muller M, et al: The effects of albumin versus hydroxyethyl starch solution on cardiorespiratory and circulatory variables in critically ill patients. Anesth Analg 1996; 83:254-261