Recombinant plasma-type platelet-activating factor acetylhydrolase attenuates NMDA-induced hippocampal neuronal apoptosis

Journal of Neuroscience Research

Volumn 53, Issue 6, 1998, Pages 677-684

  Ogden, Field ^a   DeCoster, Mark A ^a   Bazan, Nicolas G ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Neuroprotection; NMDA receptor; Platelet activating factor acetylhydrolase

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; DIZOCILPINE; DNA; FLUORESCEIN ISOTHIOCYANATE; HISTONE; N METHYL DEXTRO ASPARTIC ACID; PROPIDIUM IODIDE; RECOMBINANT ENZYME; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DEGENERATIVE DISEASE; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPILEPSY; FLUORESCENCE MICROSCOPY; HIPPOCAMPUS; NERVOUS SYSTEM INJURY; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; APOPTOSIS; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; OSMOLAR CONCENTRATION; PHOSPHOLIPASES A; RATS; RECOMBINANT PROTEINS;

EID: 0032530678     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19980915)53:6<677::AID-JNR6>3.0.CO;2-2     Document Type: Article

References (36)

1. Bazan NG (1995): Inflammation: A signal terminator. Nature 374:501-502.
2. Bazan NG (1997): Lipid messengers and prostaglandin endoperoxide synthase-2 in neuronal cell death. In Primer Cerebrovascular Diseases. M Welsh, L Chaplan, D Reis, B Siesjö, B Weir (eds), Academic Press, pp 1322-1326.
3. Bazan NG, Allan G (1998): Platelet-activating factor and other bioactive lipids. In Cerebrovascular Disease, Pathophysiology, Diagnosis and Management. MD Ginsberg, J Bogousslavsky (eds), Chapter 37, Maiden, Massachusetts: Blackwell Science Publishers, pp 532-555, 1998.
4. Bazan NG, Fletcher BS, Herschman HR, Mukherjee P (1994): Platelet-activating factor and retinoic acid synergistically activate the inducible prostaglandin synthase gene. Proc Natl Acad Sci USA 91: 5252-5256.
5. Bazan NG, Rodriguez de Turco EB, Allan G (1995): Mediators of injury in neurotrauma: Intracellular signal transduction and gene expression. J Neurotrauma 12:789-911.
6. Cao Y, Stafforini DM, Zimmerman GA, McIntyre TM, Prescott SM (1998): Expression of plasma platelet-activating factor acetylhydrolase is transcriptionally regulated by mediators of inflammation. J Biol Chem 273:4012-4020.
7. Clark GD, Happel LT, Zorumski CF, Bazan NG (1992): Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor. Neuron 9:1211-1216.
8. DeCoster MA, Yourick DL (1994): Development of glutamate-stimulated phosphoinositol metabolism in primary neuronal and primary astrocyte cultures. Int J Dev Neurosci 12:227-233.
9. Doucet JP, Squinto SP, Bazan NG (1990): FOS-JUN and the primary genomic response in the nervous system: Physiological role and pathophysiological significance. Mol Neurobiol 4:27-55.
10. Epstein L, Gendelman H (1993): Human immunodeficiency virus type 1 infection of the nervous system: Pathogenetic mechanisms. Ann Neurol 33:429-436.
11. Gelbard HA, Nottet HS, Swindells S, Jett M, Dzenko KA, Genis P, White R, Wang L, Choi YB, Zhang D (1994): Platelet-activating factor: A candidate human immunodeficiency virus type 1-induced neurotoxin. J Virol 4628-4635.
12. Gilboe DD, Kintner D, Fitzpatrick JH, Emoto SE, Esanu A, Braquet PG, Bazan NG (1991): Recovery of postischemic brain metabolism and function following treatment with a free radical scavenger and platelet-activating factor antagonists. J Neurochem 56: 311-319.
13. Hattori M, Arai H, Inoue K (1993): Purification and characterization of bovine brain platelet-activating factor acetylhydrolase. J Biol Chem 268:18748-18753.
14. Hattori M, Adachi H, Tsujimoto M, Arai H, Inoue K (1994a): Miller-Deiker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase. Nature 370:216-218.
15. Hattori M, Adachi H, Tsujimoto M, Arai H, Inoue K (1994b): The catalytic subunit of bovine brain platelet-activating factor acetylhydrolase is a novel type of serine esterase. J Biol Chem 269:23150-23155.
16. Heery JM, Kozak M, Stafforini DM, Jones DA, Zimmerman GA, McIntyre TM, Prescott SM (1995): Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells. J Clin Invest 96:2322-2330.
17. Izquierdo I, Fin C, Schmilz PK, DaSilva RC, Jerusalinsky D, Quillfeldt JA, Ferreira MBG, Medina JH, Bazan NG (1995): Memory enhancement by intrahippocampal, intraamygdala, or intraentorhinal infusion of platelet-activating factor measured in an inhibitory avoidance task. Proc Natl Acad Sci USA 92:5047-5051.
18. Kornecki E, Ehrlich YH (1988): Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor. Science 240:1792-1794.
19. Lipton SA (1994): HIV-related neuronal injury. Potential therapeutic intervention with calcium channel antagonists and NMDA antagonists. Mol Neurobiol 8:181-196.
20. Marcheselli VL, Bazan NG (1996): Sustained induction of prostaglandin endoperoxide synthase-2 by seizures in hippocampus: Inhibition by a platelet-activating factor antagonist. J Biol Chem 271:24794-24799.
21. Matsuzawa A, Hattori K, Aoki J, Arai H, Inoue K (1997): Protection against oxidative stress-induced cell death by intracellular platelet-activating factor-acetylhydrolase II. J Biol Chem 272: 32315-32320.
22. Ogden F, DeCoster MA, Bazan NG (1997a): Recombinant platelet-activating factor acetylhydrolase (rPAF-AH) decreases NMDA-induced apoptosis in primary hippocampal neurons. Experimental Biology, New Orleans, LA, Faseb J 11:2952.
23. Ogden F, DeCoster MA, Bazan NG (1997b): Neuroprotection by recombinant platelet-activating factor acetylhydrolase (rPAF-AH) on NMDA-induced excitotoxicity in hippocampal neurons. Soc Neurosci 23:1667.
24. Packard MG, Teather L, Bazan NG (1996): Intra-caudate nucleus injections of platelet-activating factor and the PAF antagonist BN 52021 on memory. Neurobiol Learn Mem 66:176-82.
25. Panetta T, Marcheselli VL, Braquet P, Spinnewyn B, Bazan NG (1987): Effects of a platelet-activating factor antagonist (BN 52021): on free fatty acids, diacylglycerols, polyphosphoinositides and blood now in the gerbil brain: Inhibition of ischemia-reperfusion induced cerebral injury. Biochem Biophys Res Comm 149:580-587.
26. Prehn JH, Krieglstein J (1993): Platelet-activating factor antagonists reduce excitotoxic damage in cultured neurons from embryonic chick telencephalon and protect the rat hippocampus and neocortex from ischemic injury in vivo. J Neurosci Res 34:179-188.
27. Prescott SM, Zimmerman GA, McIntyre TM (1990): Platelet-activating factor. J Biol Chem 265:17381-17384.
28. Smiley PL, Stremler KE, Prescott SM, Zimmerman GA, McIntyre TM (1991): Oxidatively-damaged phosphatidylcholines activate human neutrophils through the receptor for phosphatidylcholine. J Biol Chem 266:11104-11110.
29. Squinto SP, Block AL, Braquet P, Bazan NG (1989): Platelet-activating factor stimulates a Fos/Jun/AP-1 transcriptional signaling system in human neuroblastoma cells. J Neurosci Res 24:558-566.
30. Stafforini DM, Prescott SM, Zimmerman GA McIntyre TM (1991): PAF acetylhydrolase in human tissues and blood cells. Lipids 26:979-985.
31. Stafforini DM, Rollins EN, Prescott SM, McIntyre TM (1993): The platelet-activating factor acetylhydrolase from human erythrocytes. Purification and properties. J Biol Chem 268:3857-3865.
32. Stafforini DM, McIntyre TM, Zimmerman GA, Prescott SM (1997): Platelet-activating factor acetylhydrolases. J Biol Chem 272: 17895-17898.
33. Tjoelker LW, Wilder C, Eberhardt C, Stafforini DM, Dietsch G, Schimpf B, Hooper S, Trong HL, Cousens LS, Zimmerman GA, Yamada Y, McIntyre TM, Prescott SM, Gray PW (1995): Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature 374:549-553.
34. Tso MO, Zhang C, Abler AS, Chang C-J, Wong F, Chang G-Q, Lam TT (1994): Apoptosis leads to photoreceptor degeneration in inherited retinal dystrophy of RCS rats. Invest Ophthalmol Vis Sci 35:2693-2699.
35. Wieraszko A, Li G, Kornecki E, Hogan MV, Ehrlich YH (1993): Long-term potentiation in the hippocampus induced by platelet-activating factor. Neuron 10:553-557.
36. Zimmerman GA, Prescott S, McIntyre TM (1994): Oxidatively fragmented phospholipids as inflammatory mediators: The dark side of polyunsaturated lipids. J Nutr 125:1661S-1665S.