Extended embryo culture reduces the implantation rate on day 4 and day 5 when only a maximum of three embryos are cultured beyond the pronuclear stage

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 124, Issue 1, 2006, Pages 65-69

  Montag, Markus ^a   Ven, Katrin Van Der ^a   Dorn, Christoph ^a   Ven, Hans Van Der ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Embryo transfer; Human; In vitro fertilization; Sequential culture medium; Transfer on day 3, 4, 5

Indexed keywords

ADULT; ANALYSIS OF VARIANCE; ARTICLE; CHI SQUARE TEST; CONTROLLED STUDY; EMBRYO CULTURE; FEMALE; FERTILIZATION IN VITRO; HUMAN; MAJOR CLINICAL STUDY; NIDATION; PREGNANCY RATE; PRIORITY JOURNAL; PROSPECTIVE STUDY; ZYGOTE;

EID: 29644445149     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2005.08.022     Document Type: Article

References (28)

1. R.G. Edwards S.A. Brody Principles and practice of assisted human reproduction 1995 Saunders Philadelphia 425 518
2. K. Bertheussen, F. Forsdahl, and J.M. Maltau In vitro fertilization. New media for embryo culture to blastocyst stage Proceedings of the Xth Congress on In Vitro Fertilization and Assisted Reproduction Vancouver 1997 199 204
3. G.M. Jones, A.O. Trounson, and D.K. Gardner Evolution and culture protocol for successful blastocyst development and pregnancy Hum Reprod 13 1998 169 177
4. D.K. Gardner, W.B. Schoolcraft, and L. Wagley A prospective randomized trial of blastocyst culture and transfer in in vitro fertilization Hum Reprod 13 1998 3434 3440
5. B. Balaban, B. Urman, and A. Sertac Blastocyst quality affects the success of blastocyst-stage embryo transfer Fertil Steril 74 2000 282 287
6. A.A. Milki, M.D. Hinckley, and J.D. Fisch Comparison of blastocyst transfer with day 3 embryo transfer in similar patient populations Fertil Steril 73 2000 126 129
7. M. Plachot, J. Belaisch-Allart, and J.M. Mayenga Blastocyst stage transfer: the real benefits compared with early embryo transfer Hum Reprod 6 15 Suppl. 2000 24 30
8. I. Van Der Auwera, S. Debrock, and C. Spiessens A prospective randomized study: day 2 versus day 5 embryo transfer Hum Reprod 17 2002 1507 1512
9. S. Coskun, J. Hollanders, and S. Al-Hassan Day 5 versus day 3 embryo transfer: a controlled randomized trial Hum Reprod 15 2000 1947 1952
10. G.J. Huisman, Fauser BCJM, and J.C. Eijkemans Implantation rates after in vitro fertilization and transfer of a maximum of two embryos that have undergone three to five days of culture Fertil Steril 73 2000 117 122
11. M. Bungum, L. Bungum, P. Humaidan, and C. Yding Andersen Day 3 versus day 5 embryo transfer: a prospective randomized study Reprod Biomed Online 7 2003 98 104
12. M. Montag, K. van der Ven, and S. Ved Success of intracytoplasmic sperm injection in couples with male and/or female chromosome aberrations Hum Reprod 12 1997 2635 2640
13. M. Montag, M. Kupka, K. van der Ven, and H. van der Ven Embryo transfer on day 3 using low versus high fluid volume Eur J Obstet Gynecol Reprod Biol 102 2002 57 60
14. J. Tesarik, and E. Greco The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology Hum Reprod 14 1999 1318 1323
15. M. Montag, H. van der Ven on behalf of the German Pronuclear Morphology Study Group Evaluation of pronuclear morphology as the only selection criterion for further embryo culture and transfer: results of a prospective multicentre study Hum Reprod 16 2001 2384 2389
16. C.V. Steer, C.L. Mills, and S.L. Tan The cumulative embryo score: a predictive embryo scoring technique to select the optimal number of embryos to transfer in an in-vitro fertilization and embryo transfer programme Hum Reprod 7 1992 117 119
17. S. Ziebe, K. Petersen, and S. Lindenberg Embryo morphology or cleavage stage: how to select the best embryo for transfer after in-vitro fertilization Hum Reprod 12 1997 1545 1549
18. P.M. Rijnders, and CA.M. Jansen The predictive value of day 3 embryo morphology regarding blastocyst formation, pregnancy and implantation rate after day 5 transfer following in-vitro fertilization or intracytoplasmic sperm injection Hum Reprod 13 1998 2869 2873
19. J. Graham, T. Han, and R. Porter Day 3 morphology is a poor predictor of blastocyst quality in extended culture Fertil Steril 74 2000 495 497
20. B.S. Shapiro, D.C. Harris, and K.S. Richter Predictive value of 72-h blastomere cell number on blastocyst development and success of subsequent transfer based on the degree of blastocyst development Fertil Steril 73 2000 582 586
21. R. Boostanfar, J.K. Jain, and C.C. Slater The prognostic significance of day 3 embryo cleavage stage on subsequent blastocyst development in a sequential culture system J Assist Reprod Genet 18 2001 548 550
22. C. Racowsky, K.V. Jackson, and N.A. Cekleniak The number of eight-cell embryos is a key determinant for selecting day 3 or day 5 transfer Fertil Steril 73 2000 558 564
23. B. Balaban, B. Urman, and C. Alatas Blastocyst transfer of poor-quality cleavage-stage embryos results in higher implantation rates Fertil Steril 75 2001 514 518
24. U. Zollner, K.P. Zollner, and G. Hartl The use of a detailed zygote score after IVF/ICSI to obtain good quality balstocysts: the German experience Hum Reprod 17 2002 1327 1333
25. L. Scott, R. Alvero, M. Leondires, and B. Miller The morphology of human pronuclear embryos is positively related to blastocyst development and implantation Hum Reprod 15 2000 2394 2403
26. D.K. Gardner, P. Vella, and M. Lane Culture and transfer of human blastocysts increases implantation rates and reduces the need for multiple embryo transfers Fertil Steril 69 1998 84 88
27. G.M. Jones, A.O. Trounson, N. Lolatgis, and C. Wood Factors affecting the success of human blastocyst development and pregnancy following in vitro fertilization and embryo transfer Fertil Steril 70 1998 1022 1029
28. B. Kovacic, V. Vlaisavljevic, M. Reljic, and V. Gavric Lovrec Clinical outcome of day 2 versus day 5 transfer in cycles with one or two developed embryos Fertil Steril 77 2002 529 536