Evaluation of pronuclear morphology as the only selection criterion for further embryo culture and transfer: Results of a prospective multicentre study

Human Reproduction

Volumn 16, Issue 11, 2001, Pages 2384-2389

  Montag, M ^a   Van Der Ven, H ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

ICSI; Implantation; IVF; Maternal age; Pronuclear morphology

Indexed keywords

ADULT; ARTICLE; CELL STRUCTURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; EMBRYO TRANSFER; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; INTRACYTOPLASMIC SPERM INJECTION; MATERNAL AGE; MULTICENTER STUDY; NIDATION; PREGNANCY; PRONUCLEUS; PROSPECTIVE STUDY; ZYGOTE;

EID: 0035152148     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/16.11.2384     Document Type: Article

References (19)

1. Oocyte polarity and cell determination in early mammalian embryos
2. Culture and transfer of human blastocysts increases implantation rates and reduces the need for multiple embryo transfers
3. Nucleolar structure
4. Implantation rates after in vitro fertilization and transfer of a maximum of two embryos that have undergone three to five days of culture
5. Clinical use of a pronuclear score following intracytoplasmic sperm injection: Impact on pregnancy rates under the conditions of the German embryo protection law
6. Timing of oocyte activation, pronucleus formation and cleavage in humans after intracytoplasmic sperm injection (ICSI) with testicular spermatozoa and after ICSI or in-vitro fertilization on sibling oocytes with ejaculated spermatozoa
7. Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography
8. The number of eight-cell embryos is a key determinant for selecting day 3 or day 5 transfer
9. Early cleavage of human embryos to the two-cell stage after intracytoplasmic sperm injection as an indicator of embryo viability
10. The successful use of pronuclear embryo transfers the day following oocyte retrieval
11. The morphology of human pronuclear embryos is positively related to blastocyst development and implantation
12. Predictive value of 72-hour blastomere cell number on blastocyst development and success of subsequent transfer based on the degree of blastocyst development
13. The cumulative embryo score: A predictive embryo scoring technique to select the optimal number of embryos to transfer in an in-vitro fertilization and embryo transfer programme
14. Development of human male pronucleus: Ultrastructure and timing
15. Assembly of the nucleolar precursor bodies in human male pronuclei is correlated with an early RNA synthetic activity
16. The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology
17. Embryos with high implantation potential after intracytoplasmic sperm injection can be recognized by a simple, non-invasive examination of pronuclear morphology
18. Nuclear and cytoplasmic dynamics of sperm penetration, pronuclear formation and microtubule organisation during fertilization and early preimplantation development in the human
19. Zygote evaluation: An efficient tool for embryo selection