Towards the rational design of MRI contrast agents: A practical approach to the synthesis of gadolinium complexes that exhibit optimal water exchange

Dalton Transactions

Volumn , Issue 24, 2005, Pages 3829-3837

  Woods, Mark ^a,b   Botta, Mauro ^c   Avedano, Stefano ^c   Wang, Jing ^b   Sherry, A Dean ^b  

^a Macrocyclics   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM; MAGNETIC RESONANCE IMAGING; REACTION KINETICS; SYNTHESIS (CHEMICAL); WATER;

COORDINATION GEOMETRY; OPTIMAL WATER EXCHANGE; STERIC ENCUMBRANCE; TWISTED SQUARE ANTIPRISMATIC (TSAP);

COMPLEXATION;

1,4,7,10 TETRAAZACYCLODODECANE; 2 (4 NITROBENZYL) 1,4,7,10 TETRAAZACYCLODODECANE N,N',N'',N''' TETRAACETIC ACID; 2-(4-NITROBENZYL)-1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETIC ACID; ALKYLATING AGENT; CONTRAST MEDIUM; GADOLINIUM 1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE; GADOTERIC ACID; HETEROCYCLIC COMPOUND; LIGAND; NITROBENZENE DERIVATIVE; ORGANOMETALLIC COMPOUND; WATER;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; STEREOISOMERISM; SYNTHESIS; TEMPERATURE;

ALKYLATING AGENTS; CONTRAST MEDIA; HETEROCYCLIC COMPOUNDS; KINETICS; LIGANDS; MAGNETIC RESONANCE IMAGING; MOLECULAR STRUCTURE; NITROBENZENES; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM; TEMPERATURE; WATER;

EID: 29644444021     PISSN: 14779226     EISSN: 14779234     Source Type: Journal    
DOI: 10.1039/b510778d     Document Type: Article

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