Insulin-like growth factor I promoter polymorphism, risk of stroke, and survival after stroke: The Rotterdam study

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 77, Issue 1, 2006, Pages 24-27

  Van Rijn, M J E ^a   Slooter, A J C ^a   Bos, M J ^a   Catarino, C F B S ^a   Koudstaal, P J ^a   Hofman, A ^a   Breteler, M M B ^a   Van Duijn, C M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C;

ADULT; AGE DISTRIBUTION; AGED; ALLELE; ARTICLE; CEREBROVASCULAR ACCIDENT; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEATH; FEMALE; FOLLOW UP; GENDER; GENETIC POLYMORPHISM; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; SAMPLE SIZE; STATISTICAL SIGNIFICANCE; STROKE; SURVIVAL RATE; SURVIVAL TIME; WILD TYPE;

AGED; ALLELES; CEREBROVASCULAR ACCIDENT; FEMALE; FOLLOW-UP STUDIES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); REGRESSION ANALYSIS; RISK FACTORS; SURVIVAL RATE;

EID: 29644433696     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2005.067447     Document Type: Article

References (28)

1. Ferns GA, Motani AS, Anggard EE. The insulin-like growth factors: their putative role in atherogenesis. Artery 1991;18(4):197-225.
2. Janssen JA, Stolk RP, Pols HA, et al. Serum total IGF-I, free IGF-I, and IGFB-1 levels in an elderly population: relation to cardiovascular risk factors and disease. Arterioscler Thromb Vasc Biol 1998;18(2):277-82.
3. Bayes-Genis A, Conover CA, Schwartz RS. The insulin-like growth factor axis: a review of atherosclerosis and restenosis. Circ Res 2000;86(2):125-30.
4. Juul A, Scheike T, Davidsen M, et al. Low serum insulin-like growth factor I is associated with increased risk of ischaemic heart disease: a population-based case-control study. Circulation 2002;106(8):939-44.
5. Bai H, Pollman MJ, Inishi Y, et al. Regulation of vascular smooth muscle cell apoptosis. Modulation of bad by a phosphatidylinositol 3-kinase-dependent pathway. Circ Res 1999;85(3):229-37.
6. Foster J, Rich CB, Florini JR. Insulin-like growth factor I, somatomedin C, induces the synthesis of tropoelastin in aortic tissue. Coll Relat Res 1987;7(3):161-9.
7. Conn KJ, Rich CB, Jensen DE, et al. Insulin-like growth factor-I regulates transcription of the elastin gene through a putative retinoblastoma control element. A role for Sp3 acting as a repressor of elastin gene transcription. J Biol Chem 1996;271(46):28853-60.
8. Gluckman P, Klempt N, Guan J, et al. A role for IGF-I in the rescue of CNS neurons following hypoxic-ischaemic injury. Biochem Biophys Res Commun 1992;182(2):593-9.
9. Liu XF, Fawcett JR, Thorne RG, et al. Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion. Neurosci Lett 2001;308(2):91-4.
10. Schabitz WR, Hoffmann TT, Heiland S, et al. Delayed neuroprotective effect of insulin-like growth factor-I after experimental transient focal cerebral ischemia monitored with MRI. Stroke 2001;32(5):1226-33.
11. Denti L, Annoni V, Cattadori E, et al. Insulin-like growth factor 1 as a predictor of ischaemic stroke outcome in the elderly. Am J Med 2004;117(5):312-7.
12. Schwab S, Spranger M, Krempien S, et al. Plasma insulin-like growth factor I and IGF binding protein 3 levels in patients with acute cerebral ischaemic injury. Stroke 1997;28(9):1744-8.
13. Janssen JA, Lamberts SW. The role of IGF-I in the development of cardiovascular disease in type 2 diabetes mellitus: is prevention possible? Eur J Endocrinol 2002;146(4):467-77.
14. Vaessen N, Heutink P, Janssen JA, et al. A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction. Diabetes 2001;50(3):637-42.
15. Schut AF, Janssen JA, Deinum J, et al. Polymorphism in the promoter region of the insulin-like growth factor I gene is related to carotid intima-media thickness and aortic pulse wave velocity in subjects with hypertension. Stroke 2003;34(7):1623-7.
16. Hofman A, Grobbee DE, de Jong PT, et al. Determinants of disease and disability in the elderly: the Rotterdam Elderly Study. Eur J Epidemiol 1991;7(4):403-22.
17. Rietveld I, Janssen JA, Hofman A, et al. A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels. Eur J Endocrinol 2003;148(2):171-5.
18. Hollander M, Bots ML, Del Sol Al, et al. Carotid plaques increase the risk of stroke and subtypes of cerebral infarction in asymptomatic elderly: the Rotterdam study. Circulation 2002;105(24):2872-7.
19. Bots ML, Looman SJ, Koudstaal PJ, et al. Prevalence of stroke in the general population. The Rotterdam Study. Stroke 1996;27(9):1499-501.
20. Clark TG, Altman DG, De Stavola BL. Quantification of the completeness of follow-up, Lancet 2002;359(9314):1309-10.
21. Adams HP Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993;24(1):35-41.
22. WHO. International statistical classification of diseases and related health problems, 10th revision. WHO, Geneva, 1992.
23. Raymond M, Rousset F. GENEPOP-package, version 1.2. Montpelier, France: Laboratoire de Genetique et Environment, 1995.
24. Bronnum-Hansen H, Davidsen M, Thorvaldsen P. Long-term survival and causes of death after stroke. Stroke 2001;32(9):2131-6.
25. Hardie K, Hankey GJ, Jamrozik K, et al. Ten-year survival after first-ever stroke in the Perth community stroke study. Stroke 2003;34(8):1842-6.
26. Zackenfels K, Oppenheim RW, Rohrer H. Evidence for an important role of IGF-I and IGF-II for the early development of chick sympathetic neurons. Neuron 1995;14(4):731-41.
27. Liu XF, Fawcett JR, Thorne RG, et al. Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischaemic damage. J Neurol Sci 2001;187(1-2):91-7.
28. Tagami M, Ikeda K, Nara Y, et al. Insulin-like growth factor-I attenuates apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats. Lab Invest 1997;76(5):613-7.