Symmetrical and asymmetrical bisphosphonate esters. Synthesis, selective hydrolysis, and isomerization

Monatshefte fur Chemie

Volumn 137, Issue 1, 2006, Pages 105-116

  Abdou, Wafaa M ^a   Ganoub, Neven A ^a   Fahmy, Amin F ^b   Shaddy, Abeer A ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b Ain Shams University   (Egypt)

Author keywords

Bone mineral affinity; Carbanions; Drug research; Methyl 1,1 bisphosphonates

Indexed keywords

EID: 29644432122     PISSN: 00269247     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00706-005-0403-y     Document Type: Article

References (27)

1. a) Lovdah MJ, Pietrzyk DJ (1999) J Chromatog A 850: 143;
2. b) van Beek ER, Löwik CWGM, Ebetino FH, Papapoulos SE (1998) Bone 23: 437;
3. c) Cermak DM, Wiemer DF, Lewis K, Hohl RJ (2000) Bioorg Med Chem 8: 2729;
4. d) Vincenzi B, Santini D, Avvisati G, Baldi A, La Cesa A, Tonini G (2003) Med Hypotheses 61: 98;
5. e) Troutman JM, Chehade KAH, Kiegel K, Andres DA, Spielmann HP (2004) Bioorg Med Chem Lett 14: 4979;
6. f) Russell RGG (1999) Phosph Sulfur Silicon 144-146: 793;
7. g) Dombrecht EJ, Cos P, Berghe DV, van Offel JF, Schnerwegh AJ, Bridts CH, Stevens WJ, Declerch LS (2004) Biochem Biophys Res Commun 314: 675
8. AJ Coukell A Markham 1998 Drug Aging 12 149
9. Abdou WM, Ganoub NAF, Elkhoshnieh YO (2003) Synlett 785
10. a) Elkhoshnieh YO, Hennawy IT, Abdou WM (1995) Heterocyclic Communs 1: 167;
11. b) Elkhoshnieh YO, Ibrahim YA, Abdou WM (1995) Phosph Sulfur Silicon 101: 67
12. WM Abdou AA Shaddy 2001 Synth Commun 31 13
13. a) Abdou WM, Elkhoshnieh YO, Kamel AA (1996) Phosph Sulfur Silicon 119: 225;
14. b) Abdou WM, Fahmy AFM, Kamel AA (2002) Heteroatom Chem 13: 357
15. a) Neidlein R, Eichinger T (1992) Monatsh Chem 123: 1037;
16. b) Dufau C, Sturtz G (1992) Phosph Sulfur Silicon 69: 93
17. a) Griffiths DV, Griffiths PA, Karim K, Harris JE (1997) J Chem Soc Perkin Trans 1, 2539;
18. b) Griffiths DV, Whitehead BJ, Tebby JC (1992) J Chem Soc Perkin Trans 1, 479
19. C Yuan C Li 1992 Phosph Sulfur Silicon 69 75
20. a) Ebetino FH, Dansereau SM (1995) In: Bijvoet O, Fleisch HA, Canfield RE, Russell RGG (eds) Bisphosphonate on Bones. Elsevier, Amesterdam, p 139;
21. b) Ebetino FH, Francis MD, Rogers MJ, Russell RGG (1998) Rev Contemp Pharmacother 9: 233
22. Ford-Moore AH, Williams JH (1947) J Chem Soc 1465
23. M Sahni HL Guenther H Fleisch P Collin TJ Martin 1993 J Clin Invest 91 2004
24. RC Muehlbauer F Bauss R Schenk M Janner E Bosies K Strein HA Fleisch 1991 J Bone Min Res 6 1003
25. PV Laakso R Robinson HP Vandrewala 1957 Tetrahedron 1 103
26. TB Johnson SH Clapp 1908 J Biol Chem 5 49
27. A Baeyer 1879 Chem Ber 12 456