Adaptation to pregnancy leads to attenuated rat uterine artery smooth muscle sensitivity to oxytocin

American Journal of Obstetrics and Gynecology

Volumn 194, Issue 1, 2006, Pages 252-260

  Vedernikov, Yuri P ^a   Betancourt, Ancizar ^a   Wentz, Melissa J ^a   Saade, George R ^a   Garfield, Robert E ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Oxytocin; Receptors; Uterine artery; Vascular adaptation to pregnancy; Vasopressin

Indexed keywords

OXYTOCIN;

ADAPTATION; ARTICLE; ATTENUATION; BLOOD VESSEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; SECOND TRIMESTER PREGNANCY; SMOOTH MUSCLE; THIRD TRIMESTER PREGNANCY; UTERINE ARTERY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; AORTA, THORACIC; ARGININE VASOPRESSIN; ARTERIES; COMPUTER SYSTEMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FEMORAL ARTERY; MUSCLE, SMOOTH, VASCULAR; OSMOLAR CONCENTRATION; OXYTOCICS; OXYTOCIN; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OXYTOCIN; RECEPTORS, VASOPRESSIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UTERUS; VASOCONSTRICTION; VASOPRESSINS;

EID: 29544438290     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2005.05.006     Document Type: Article

References (26)

1. G. Gimpl, and F. Fahrenholz The oxytocin receptor system: structure, function, and regulation Physiol Rev 181 2000 629 683
2. M.S. Soloff, M. Alexandrova, and M.J. Fernstrom Oxytocin receptors: triggers for parturition and lactation? Science 204 1979 1313 1315
3. A.R. Fuchs, F. Fuchs, P. Husslein, M.S. Soloff, and M. Fernstrom Oxytocin receptors and human parturition: a dual role for oxytocin in the initiation of human labor Science 215 1982 1396 1398
4. A.R. Fuchs, P. Husslein, and F. Fuchs Oxytocin and the initiation of parturition: II, stimulation of prostaglandin production in human decidua by oxytocin Am J Obstet Gynecol 141 1981 694 697
5. J. Gutkowska, M. Jankowski, S. Makaddam-Daher, and S.M. McCann Oxytocin as cardiovascular hormone Braz J Med Biol Res 6 2000 625 633
6. W. Jankowski, D. Wang, F. Hajjar, S. Mukaddam-Dahler, S.M. McCann, and J. Gutkowska Oxytocin and its receptors are synthesized in rat vasculature Proc Natl Acad Sci U S A 97 2000 6207 6211
7. N.J. Cicutti, C.E. Smyth, O.P. Rosaeg, and M. Wilkinson Oxytocin receptor binding in rat and human heart Can J Cardiol 15 1999 1267 1273
8. W.B. Stam, P.H. Van der Graaf, and P.R. Saxena Characterization of receptors mediating contraction of the rat isolated small mesenteric artery and aorta to arginine vasopressin and oxytocin Br J Pharmacol 25 1998 865 873
9. M. Thibonnier, D.M. Conarty, J.A. Preston, C.L. Plesnicher, R.A. Dweik, and S.C. Erzurum Human vascular endothelial cells express oxytocin receptors Endocrinology 140 1999 1301 1309
10. L.C. Michelini, M.C. Marcelo, J. Amico, and M. Morris Oxytocinergic regulation of cardiovascular function: studies in oxytocin deficient mice Am J Physiol 284 2003 H2269 H2276
11. B.F. Mitchell, and B. Schmid Oxytocin and its receptor in the process of parturition J Soc Gynecol Invest 8 2001 122 133
12. M. Petersson Cardiovascular effects of oxytocin Prog Brain Res 139 2002 281 288
13. R.E. Van Kesteren, and W.P.M. Geraerts Molecular evolution of ligand-binding specificity in the vasopressin/oxytocin receptor family Ann New York Acad Sci 839 1998 25 35
14. 1 vasopressin receptor antagonist SR49059 in hypertensive patients Hypertension 34 1999 1293 1300
15. W.Y. Chan, N.C. Wo, S. Stoev, L.L. Cheng, and M. Manning Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays Exp Physiol 85 2000 7S 18S
16. R. Acher Molecular evolution of biologically active polypeptides Proc R Soc Lond B Biol Sci 210 1980 21 43
17. Y.L. Chen, C. Shepherd, W. Spinelli, and F.M. Lai Oxytocin and vasopressin constrict rat isolated resistance arteries by activating vasopressin V1A receptors Eur J Pharmacol 376 1999 45 51
18. M.E. Miller, S.T. Davidge, and B.F. Mitchell Oxytocin does not directly affect vascular tone in vessels from non-pregnant and pregnant rats Am J Physiol 282 2002 H1223 H1228
19. A. Jovanovic, S. Jovanovic, and L. Grbovic Characterization of oxytocin actions in guinea pig isolated uterine artery: the effect of pregnancy Br J Pharmacol 343 1998 35 42
20. M. Ali, I. Buhimschi, K. Chwalisz, and R.E. Garfield Changes in expression of the nitric oxide synthase isoforms in rat uterus and cervix during pregnancy and parturition Mol Hum Reprod 3 1997 995 1003
21. K. Bankowski, M. Manning, J. Seto, J. Halder, and W.H. Sawyer Design and synthesis of potent in vivo antagonists of oxytocin Int J Pept Protein Res 16 1980 382 391
22. M. Kruszynski, B. Lammek, M. Manning, J. Seto, J. Haldar, and W.H. Sawyer [1-beta-Mercapto-beta, beta-cyclopentamethylenepropionic acid), 2-(O-methyl) tyrosin] arginine-vasoprtessin and [1-beta-mercapto-beta, beta- cyclopentamethylenepropionic acid)] arginine-vasopressin, two highly potent antagonists of the vasopressor response to arginine-vasopressin J Med Chem 23 1980 364 368
23. 1a vasopressin receptor differentiate agonist vs. antagonist ligand binding Eur J Biochem 267 2000 4253 4263
24. 1b receptor ligands for pharmacological, functional and structural investigations J Neuroendocrinol 16 2004 356 361
25. A. Jovanovic, L. Grbovic, S. Jovanovic, and I. Zicic Effect of pregnancy on vasopressin-mediated responses in guinea pig uterine arteries with intact and denuded endothelium Eur J Pharmacol 280 1995 101 111
26. T. Higuchi, Y. Tadokoro, K. Honda, and H. Negoro Detailed analysis of blood oxytocin levels during suckling and parturition in the rat J Endocrinol 110 1986 251 256