Enhanced growth in NS0 cells expressing aminoglycoside phosphotransferase is associated with changes in metabolism, productivity, and apoptosis

Biotechnology and Bioengineering

Volumn 92, Issue 5, 2005, Pages 589-599

  Veraitch, Farlan S ^a   Al Rubeai, Mohamed ^a,b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Aminoglycoside phosphotransferase; Apoptosis; BCL 2; Cell cycle; G418; Metabolism; Neo; NS0 myeloma cells

Indexed keywords

BIOTECHNOLOGY; CELLS; ENZYMES; GENES; GLUCOSE; METABOLISM;

AMINOGLYCOSIDE PHOSPHOTRANSFERASE; APOPTOSIS; BCL-2; CELL CYCLE; G418; NEO; NS0 MYELOMA CELLS;

CYTOLOGY;

AMINOGLYCOSIDE PHOSPHOTRANSFERASE; CHIMERIC ANTIBODY; GENE PRODUCT; GLUCOSE; GLUTAMIC ACID; INHIBITOR OF APOPTOSIS PROTEIN; PHOSPHOTRANSFERASE; PROTEIN BCL 2; RECOMBINANT ENZYME; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BATCH CELL CULTURE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CLONAL VARIATION; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENETIC TRANSFECTION; GROWTH CURVE; MARKER GENE; MOUSE; NEO GENE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; GENE EXPRESSION REGULATION; GENETIC ENHANCEMENT; GENETIC MARKERS; KANAMYCIN KINASE; METABOLIC CLEARANCE RATE; MICE; MULTIPLE MYELOMA; PROTEIN ENGINEERING; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS;

ANIMALIA; MURINAE;

EID: 29544432560     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20632     Document Type: Article

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