메뉴 건너뛰기




Volumn 132, Issue 3, 2006, Pages 184-192

Cyclooxygenase-2 (COX-2) is directly involved but not decisive in proliferation of human hepatocellular carcinoma cells

Author keywords

Cyclooxygenase 2; Growth inhibition; Hepatocellular carcinoma; siRNA

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; SMALL INTERFERING RNA;

EID: 29544432032     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-005-0060-x     Document Type: Article
Times cited : (20)

References (31)
  • 2
    • 0036554862 scopus 로고    scopus 로고
    • Expressions of cyclooxygenase-2 and prostaglandin E receptors in carcinoma of the gallbladder: Crucial role of arachidonate metabolism in tumor growth and progression
    • Asano T, Shoda J, Ueda T, Kawamoto T, Todoroki T, Shimonishi M, Tanabe T et al (2002) Expressions of cyclooxygenase-2 and prostaglandin E receptors in carcinoma of the gallbladder: crucial role of arachidonate metabolism in tumor growth and progression. Clin Cancer Res 8:1157-1167
    • (2002) Clin Cancer Res , vol.8 , pp. 1157-1167
    • Asano, T.1    Shoda, J.2    Ueda, T.3    Kawamoto, T.4    Todoroki, T.5    Shimonishi, M.6    Tanabe, T.7
  • 3
    • 0034905269 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398
    • Bae SH, Jung ES, Park YM, Kim BS, Kim BK, Kim DG, Ryu WS (2001) Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398. Clin Cancer Res 7:1410-1418
    • (2001) Clin Cancer Res , vol.7 , pp. 1410-1418
    • Bae, S.H.1    Jung, E.S.2    Park, Y.M.3    Kim, B.S.4    Kim, B.K.5    Kim, D.G.6    Ryu, W.S.7
  • 4
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 5
    • 0033021515 scopus 로고    scopus 로고
    • Inhibition of prostaglandin synthesis up-regulates cyclooxygenase-2 indueced by lipopolysaccharide and peroxisomal proliferators
    • Callejas NA, Castrillo A, Bosca L, Martin-Sanz P (1999) Inhibition of prostaglandin synthesis up-regulates cyclooxygenase-2 indueced by lipopolysaccharide and peroxisomal proliferators. J Phar Exp Ther 288:1235-1241
    • (1999) J Phar Exp Ther , vol.288 , pp. 1235-1241
    • Callejas, N.A.1    Castrillo, A.2    Bosca, L.3    Martin-Sanz, P.4
  • 6
    • 0036100517 scopus 로고    scopus 로고
    • NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines
    • Cheng J, Imanishi H, Amuro Y, Hada T (2002a) NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines. Int J Cancer 99(5):755-761
    • (2002) Int J Cancer , vol.99 , Issue.5 , pp. 755-761
    • Cheng, J.1    Imanishi, H.2    Amuro, Y.3    Hada, T.4
  • 9
    • 0346993513 scopus 로고    scopus 로고
    • Induction of G0/G1 cell cycle arrest in ovarian carcinoma 1cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference
    • Denkert C, Furstenberg A, Daniel PT, Koch I, Kobel M, Weichert W, Siegert A et al (2003) Induction of G0/G1 cell cycle arrest in ovarian carcinoma 1cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference. Oncogene 22:8653-8661
    • (2003) Oncogene , vol.22 , pp. 8653-8661
    • Denkert, C.1    Furstenberg, A.2    Daniel, P.T.3    Koch, I.4    Kobel, M.5    Weichert, W.6    Siegert, A.7
  • 10
    • 0036208533 scopus 로고    scopus 로고
    • The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line
    • Fantappie O, Masini E, Sardi I, Raimondi L, Bani D, Solazzo M, Vannacci A, et al. (2002) The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line. Hepatology 35:843-852
    • (2002) Hepatology , vol.35 , pp. 843-852
    • Fantappie, O.1    Masini, E.2    Sardi, I.3    Raimondi, L.4    Bani, D.5    Solazzo, M.6    Vannacci, A.7
  • 11
    • 0034471496 scopus 로고    scopus 로고
    • Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia
    • Fosslien E (2000) Biochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia. Crit Rev Clin Lab Sci 37(5):431-502
    • (2000) Crit Rev Clin Lab Sci , vol.37 , Issue.5 , pp. 431-502
    • Fosslien, E.1
  • 12
    • 0141963117 scopus 로고    scopus 로고
    • Inhibitors of cyclo-ocygenase 2: A new class of anticancer agents
    • Gasparini G, Longo R, Sarmiento R, Morabito A (2003) Inhibitors of cyclo-ocygenase 2: a new class of anticancer agents. Lancet Oncol 4:605-615
    • (2003) Lancet Oncol , vol.4 , pp. 605-615
    • Gasparini, G.1    Longo, R.2    Sarmiento, R.3    Morabito, A.4
  • 13
    • 0034120120 scopus 로고    scopus 로고
    • The molecular perspective: Cyclooxygenase-2
    • Goodsell DS (2000) The molecular perspective: cyclooxygenase-2. Stem Cells 18:227-229
    • (2000) Stem Cells , vol.18 , pp. 227-229
    • Goodsell, D.S.1
  • 14
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ (2002) RNA interference. Nature 418:244-251
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 16
    • 0034802512 scopus 로고    scopus 로고
    • Differential expression of cyclooxygenase-2 in human bile duct epithelial cells and bile duct neoplasm
    • Hayashi N, Yamamoto H, Hiraoka N, Dono K, Ito Y, Okami J, Kondo M, et al. (2001) Differential expression of cyclooxygenase-2 in human bile duct epithelial cells and bile duct neoplasm. Hepatology 34:638-650
    • (2001) Hepatology , vol.34 , pp. 638-650
    • Hayashi, N.1    Yamamoto, H.2    Hiraoka, N.3    Dono, K.4    Ito, Y.5    Okami, J.6    Kondo, M.7
  • 17
    • 0036014815 scopus 로고    scopus 로고
    • Rationale and feasibility of Chemoprevention of hepatocellular carcinoma by cycloocygenase-2 inhibitors
    • Hu KQ (2002) Rationale and feasibility of Chemoprevention of hepatocellular carcinoma by cycloocygenase-2 inhibitors. J Lab Clin Med 139:234-243
    • (2002) J Lab Clin Med , vol.139 , pp. 234-243
    • Hu, K.Q.1
  • 18
    • 0036788542 scopus 로고    scopus 로고
    • Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells
    • Kern MA, Schubert D, Sahi D, Schoneweiss MM, Moll I, Haugg AM, Dienes HP, et al. (2002) Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells. Hepatology 36(4 Pt 1):885-894
    • (2002) Hepatology , vol.36 , Issue.4 PART 1 , pp. 885-894
    • Kern, M.A.1    Schubert, D.2    Sahi, D.3    Schoneweiss, M.M.4    Moll, I.5    Haugg, A.M.6    Dienes, H.P.7
  • 19
    • 3242809061 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice
    • Kern MA, Schoneweiss MM, Sahi D, Bahlo M, Haugg AM, Kasper HU, Dienes HP, et al. (2004) Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice. Carcinogenesis 25(7):1193-1199
    • (2004) Carcinogenesis , vol.25 , Issue.7 , pp. 1193-1199
    • Kern, M.A.1    Schoneweiss, M.M.2    Sahi, D.3    Bahlo, M.4    Haugg, A.M.5    Kasper, H.U.6    Dienes, H.P.7
  • 20
    • 0043073254 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Is there a potential for chemoprevention using cyclooxygenase-2 inhibitors?
    • Koga H (2003) Hepatocellular carcinoma: is there a potential for chemoprevention using cyclooxygenase-2 inhibitors? Cancer 98:661-667
    • (2003) Cancer , vol.98 , pp. 661-667
    • Koga, H.1
  • 21
    • 0032978469 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in human hepatocellular carcinoma; relevance to tumor dedifferentiation
    • Koga H, Sakisaka S, Ohishi M, Kawaguchi T, Taniguchi E, Sasatomi K, Harada M, et al. (1999) Expression of cyclooxygenase-2 in human hepatocellular carcinoma; relevance to tumor dedifferentiation. Hepatology 29:688-696
    • (1999) Hepatology , vol.29 , pp. 688-696
    • Koga, H.1    Sakisaka, S.2    Ohishi, M.3    Kawaguchi, T.4    Taniguchi, E.5    Sasatomi, K.6    Harada, M.7
  • 22
    • 0036955336 scopus 로고    scopus 로고
    • The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression
    • Lara-Pezzi E, Gomez-Gaviro MV, Galvez BG, Mira E, Iniguez MA, Fresno M, Martinez-A C et al (2002) The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. J Clin Invest 110:1831-1838
    • (2002) J Clin Invest , vol.110 , pp. 1831-1838
    • Lara-Pezzi, E.1    Gomez-Gaviro, M.V.2    Galvez, B.G.3    Mira, E.4    Iniguez, M.A.5    Fresno, M.6    Martinez-A, C.7
  • 23
    • 0041822007 scopus 로고    scopus 로고
    • Cyclooxygenase-2 promotes hepatocellular caricoma cell growth through AKT activation: Evidence of AKT inhibition in celecoxib-induced apoptosis
    • Leng J, Han C, Demetris AJ, Michalopoulos GK, Wu T (2003) Cyclooxygenase-2 promotes hepatocellular caricoma cell growth through AKT activation: evidence of AKT inhibition in celecoxib-induced apoptosis. Hepatology 38:756-768
    • (2003) Hepatology , vol.38 , pp. 756-768
    • Leng, J.1    Han, C.2    Demetris, A.J.3    Michalopoulos, G.K.4    Wu, T.5
  • 25
    • 0034906314 scopus 로고    scopus 로고
    • Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: Possible involvement of COX-2 in the angiogenesis of hepatitis C virus-positive cases
    • Rahman MA, Dhar DK, Yamaguchi E, Maruyama S, Sato T, Hayashi H, Ono T, et al. (2001) Coexpression of inducible nitric oxide synthase and COX-2 in hepatocellular carcinoma and surrounding liver: possible involvement of COX-2 in the angiogenesis of hepatitis C virus-positive cases. Clin Cancer Res 7:1325-1332
    • (2001) Clin Cancer Res , vol.7 , pp. 1325-1332
    • Rahman, M.A.1    Dhar, D.K.2    Yamaguchi, E.3    Maruyama, S.4    Sato, T.5    Hayashi, H.6    Ono, T.7
  • 29
    • 0036725378 scopus 로고    scopus 로고
    • Altered expression of E-caderin in hepatocellular carcinoma: Correlation with genetic alterations, beta-catenin expression, and clinical features
    • Wei Y, Van Nhieu JT, Prigent S, Srivatanakul P, Tiollais P, Buendia MA (2002) Altered expression of E-caderin in hepatocellular carcinoma: correlation with genetic alterations, beta-catenin expression, and clinical features. Hepatology 36:692-701
    • (2002) Hepatology , vol.36 , pp. 692-701
    • Wei, Y.1    Van Nhieu, J.T.2    Prigent, S.3    Srivatanakul, P.4    Tiollais, P.5    Buendia, M.A.6
  • 30
    • 0033590207 scopus 로고    scopus 로고
    • The role of cyclooxygenases in inflammation, cancer, and development
    • Williams CS, Mann M, DuBois RN (1999) The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 18:7908-7916
    • (1999) Oncogene , vol.18 , pp. 7908-7916
    • Williams, C.S.1    Mann, M.2    DuBois, R.N.3
  • 31
    • 1542460449 scopus 로고    scopus 로고
    • IARC Press, Lyon
    • World Health Organization (2003) World cancer report 2003, IARC Press, Lyon
    • (2003) World Cancer Report 2003


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.