Anesthesia and analgesia in reptiles

Seminars in Avian and Exotic Pet Medicine

Volumn 14, Issue 4, 2005, Pages 243-262

  Mosley, Craig A E ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Analgesia; Anesthesia; Cardiopulmonary physiology; Monitoring; Perianesthetic support; Reptiles

Indexed keywords

ANIMALIA; REPTILIA;

EID: 29444447275     PISSN: 1055937X     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.saep.2005.09.005     Document Type: Article

References (138)

1. G.R. Ultsch D.C. Jackson Long-term submergence at 3 degrees C of the turtle Chrysemys picta bellii in normoxic and severely hypoxic water. III. Effects of changes in ambient PO2 and subsequent air breathing J Exp Biol 97 1982 87-99
2. J.W. Hicks A.F. Bennett Eat and run: Prioritization of oxygen delivery during elevated metabolic states Respir Physiol Neurobiol 144 2004 215-224
3. R.M. Andrews F.H. Pough Metabolism of squamate reptiles: Allometric and ecological relationships Physiol Zool 58 1985 214-231
4. L.A. Baker F.N. White Redistribution of cardiac output in response to heating in Iguana iguana Comp Biochem Physiol 35 1970 253-262
5. J.W. Hicks T. Wang Hypometabolism in reptiles: Behavioural and physiological mechanisms that reduce aerobic demands Respir Physiol Neurobiol 141 2004 261-271
6. J.W. Hicks T. Wang Hypoxic hypometabolism in the anesthetized turtle, Trachemys scripta Am J Physiol 277 1999 R18-R23
7. M. Ladyman D. Bradshaw The influence of dehydration on the thermal preferences of the Western tiger snake, Notechis scutatus J Comp Physiol [B] 173 2003 239-246
8. L.H.S. Van Mierop M. Kutsche Comparitive anatomy of the ventricular septum In: A.C.G. Wenick (ed.) The Ventricular Septum in the Heart 1981 Martinus Nijhoff Boston, MA 35-46
9. L.H.S. Van Mierop M. Kutsche Some aspects of comparative anatomy of the heart In: K. Johansen W.W. Burggren (eds.) Cardiovascular Shunts Phylogenetic, Ontogenic and Clinical Aspects 1985 Munksgaard Copenhagen 38-56
10. S.G. Comeau J.W. Hicks Regulation of central vascular blood flow in the turtle Am J Physiol 267 1994 R569-R578
11. J. Herman T. Wang A.W. Smits et al. The effects of artificial lung inflation on pulmonary blood flow and heart rate in the turtle, Trachemys scripta J Exp Biol 200 1997 2539-2545
12. J.W. Hicks A. Ishimatsu S. Molloi The mechanism of cardiac shunting in reptiles: A new synthesis J Exp Biol 199 1996 1435-1446
13. N. Heisler P. Neumann G.M. Maloiy The mechanism of intracardiac shunting in the lizard, Varanus exanthematicus J Exp Biol 105 1983 15-31
14. A. Ishimatsu J.W. Hicks N. Heisler Analysis of intracardiac shunting in the lizard, Varanus niloticus: A new model based on blood oxygen levels and microsphere distribution Respir Physiol 71 1988 83-100
15. J.W. Hicks G.M. Malvin Mechanism of intracardiac shunting in the turtle, Pseudemys scripta Am J Physiol 262 1992 R986-R992
16. P.J. Berger G. Burnstock Autonomic nervous system In: C. Gans (ed.) Biology of the Reptilia 1979 Academic Press New York, NY 1-57
17. W.W. Burggren M.L. Glass K. Johansen Pulmonary ventilation: Perfusion relationships in terrestrial and aquatic chelonian reptiles Can J Zool 55 1977 2024-2034
18. H.B. Lillywhite J.A. Donald Pulmonary blood flow regulation in an aquatic snake Science 245 1989 293-295
19. A.B. Luckhardt A.J. Carlson Studies on the visceral sensory nervous system Am J Physiol 56 1921 72-112
20. W.K. Milsom B.L. Langille D.R. Jones Vagal control of pulmonary vascular resistance in the turtle, Chrysemys scripta Can J Zool 55 1977 359-367
21. F.N. White Circulation In: C. Gans W.R. Dawson (eds.) Biology of the Reptilia, Physiology A 1976 Academic Press New York, NY 275-334
22. W. Burggren A. Farrell H.B. Lillywhite Vertebrate cardiovascular systems In: W.H. Dantzler (ed.) Handbook of Physiology. Section 13: Comparative Physiology 1997 Oxford University Press New York, NY 254-267
23. P.J. Berger The reptilian baroreceptor and its role in cardiovascular control Am Zool 27 1987 111-120
24. J.N. Stinner Cardiovascular and metabolic responses to temperature in, Coluber constrictor Am J Physiol 253 1987 R222-R227
25. J.N. Stinner D.L. Ely Blood pressure during routine activity, stress, and feeding in black racer snakes, (Coluber constrictor) Am J Physiol 264 1993 R79-R84
26. A.P. Farrell Introduction to cardica scope in lower vertebrates Can J Zool 69 1991 1981-1984
27. R.S. Seymour H.B. Lillywhite Blood pressure in snakes from different habitats Nature 264 1976 664-666
28. H.B. Lillywhite K.P. Gallagher Hemodynamic adjustments to head-up posture in the partly arboreal snake, Elaphe obsoleta J Exp Zool 235 1985 325-334
29. H.B. Lillywhite F.H. Pough Control of arterial pressure in aquatic sea snakes Am J Physiol 244 1983 R66-R73
30. R.E. Seymour Scaling of cardiovascular physiology in snakes Am Zool 27 1987 97-109
31. N.L. Anderson R.F. Wack L. Calloway et al. Cardiopulmonary effects and efficacy of propofol as an anesthetic in brown tree snakes (Boiga irregularis) Bull Assoc Reptilian Amphibian Vet 9 1999 9-15
32. P.C. Arena K.C. Richardson L.K. Cullen Anaesthesia in two species of large Australian skink Vet Rec 123 1988 155-158
33. R.A. Bennett J. Schumacher K. Hedjazi-Haring et al. Cardiopulmonary and anesthetic effects of propofol administered intraosseously to green iguanas J Am Vet Med Assoc 212 1998 93-98
34. K. Bonath Halothane inhalation anaesthesia in reptiles and its clinical control Intl Zoo Yearbook 19 1979 112-125
35. R.S. Custer M. Bush Physiologic and acid-base measures of gopher snakes during ketamine or halothane-nitrous oxide anesthesia J Am Vet Med Assoc 177 1980 870-874
36. C.A. Mosley D. Dyson D.A. Smith The cardiovascular dose-response effects of isoflurane alone and combined with butorphanol in the green iguana, (Iguana iguana) Vet Anaesth Analg 31 2004 64-72
37. M.B. Rooney G. Levine J. Gaynor et al. Sevoflurane anesthesia in desert tortoises, (Gopherus agassizii) J Zoo Wildl Med 30 1999 64-69
38. J. Schumacher H.B. Lillywhite W.M. Norman et al. Effects of ketamine HCl on cardiopulmonary function in snakes Copeia 1997 395-400
39. R. Stirl K.H. Bonath Cardiovascular, pulmonary and acid-base measurements in boa constrictors during tiletamine-zolazepam sedation 1994 5th International Congress of Veterinary Anesthesia, Guelph, Canada, Scientific Abstract 55
40. W.K. Milsom Mechanoreceptor modulation of endogenous respiratory rhythms in vertebrates Am J Physiol 259 1990 R898-R910
41. N.J. Smatresk Chemoreceptor modulation of endogenous respiratory rhythms in vertebrates Am J Physiol 259 1990 R887-R897
42. T. Wang A.W. Smits W. Burggren Pulmonary function in reptiles In: C. Gans A.S. Gaunt (eds.) Biology of the Reptilia 1998 Society for the Study of Amphibians and Reptiles Ithaca, NY 319
43. G. Shelton D.R. Jones W.K. Milsom Control of breathing in ectothermic vertebrates In: S.R. Geiger J.G. (eds.) Widdicombe Handbook of Physiology. Section 3: The Respiratory System 1986 American Physiological Society Bethesda, MD
44. S.C. Wood C.J.M. Lenfant Respiration mechanics, control and gas exchange In: C. Gans W.R. Dawson (eds.) Biology of the Reptilia, Physiology A 1976 Academic Press New York, NY 225-274
45. M.L. Glass S.C. Wood Gas exchange and control of breathing in reptiles Physiol Rev 63 1983 232-260
46. K. Johansen D. Hanson C. Lenfant Respiration in a primitive air breather, Amia calva Respir Physiol 9 1970 162-174
47. F.N. White Redistribution of cardiac output in the diving alligator Copeia 1969 567-570
48. G. Shelton W. Burggren Cardiovascular dynamics of the chelonia during apnoea and lung ventilation J Exp Biol 64 1976 323-343
49. S.F. Perry Structure and function of the reptilian respiratory system In: C. Lenfant C.M. Wood (eds.) Comparative Pulmonary Physiology. Current Concepts 1989 Marcel Dekker New York, NY 193-236
50. M.L. Glass K. Johansen Control of breathing in Acrochordus javanicus, an aquatic snake Physiol Zool 49 1976 328-340
51. J.R. Templeton W.R. Dawson Respiration in the lizard Crotaphytus collaris Physiol Zool 36 1963 104-121
52. M.L. Glass W. Burggren K. Johansen Ventilation in an aquatic and a terrestrial chelonian reptile J Exp Biol 72 1978 165-179
53. D.C. Jackson D.R. Kraus H.D. Prange Ventilatory response to inspired CO2 in the sea turtle: Effects of body size and temperature Respir Physiol 38 1979 71-81
54. D.C. Jackson S.E. Palmer W.L. Meadow The effects of temperature and carbon dioxide breathing on ventilation and acid-base status of turtles Respir Physiol 20 1974 131-146
55. D.R. Boyer Comparative effects of hypoxia on respiratory and cardiac function in reptiles Physiol Zool 39 1966 307-316
56. 2 Am J Physiol 249 1985 R323-R328
57. D.C. Jackson Ventilatory response to hypoxia in turtles at various temperatures Respir Physiol 18 1973 178-187
58. G. Benchetrit J. Armand P. Dejours Ventilatory chemoreflex drive in the tortoise, Testudo horsfieldi Respir Physiol 31 1977 183-191
59. 2 drive in the tortoise, Testudo horsfieldi J Exp Biol 87 1980 229-236
60. H.M. Frankel A. Spitzer J. Blaine et al. Respiratory response of turtles (Pseudemys scripta) to changes in arterial blood gas composition Comp Biochem Physiol 31 1969 535-546
61. 2) on recovery times in the green iguana (Iguana iguana) 2001 Zurich University of Zurich
62. M.F. Bertelsen C.A. Mosley G.J. Crawshaw et al. Inhalation anesthesia in Dumeril's monitor (Varanus dumerili) with isoflurane, sevoflurane, and nitrous oxide: Effects of inspired gases on inducion and recovery J Zoo Wildl Med 36 2005 62-68
63. N.J. Berner Oxygen consumption by mitochondria from an endotherm and an ectotherm Comp Biochem Physiol B Biochem Mol Biol 124 1999 25-31
64. D.N. Penick F.V. Paladino A.C. Steyermark et al. Thermal dependence of tissue metabolism in the green turtle (Chelonia mydas) Comp Biochem Physiol 113A 1996 293-296
65. D.J. Heard Reptile anesthesia Vet Clin North Am Exot Anim Pract 4 2001 83-117
66. P. Holz I.K. Barker J.P. Burger et al. The effect of the renal portal system on pharmacokinetic parameters in the red-eared slider, (Trachemys scripta elegans) J Zoo Wildl Med 28 1997 386-393
67. P. Holz I.K. Barker G.J. Crawshaw H. Dobson The anatomy and perfusion of the renal portal system in the red-eared slider, (Trachemys scripta elegans) J Zoo Wildl Med 28 1997 378-385
68. E.J. Chittick M.A. Stamper J.F. Beasley et al. Medetomidine, ketamine, and sevoflurane for anesthesia of injured loggerhead sea turtles 13 cases (1996-2000) J Am Vet Med Assoc 221 2002 1019-1025
69. J.F.X. Wellehan M. Lafortune C. Gunkel et al. Coccygeal vascular catheterization in lizards and crocodilians J Herpetological Med Surg 14 2004 26-28
70. L.K. Maxwell E.R. Jacobson Allometric scaling of kidney function in green iguanas Comp Biochem Physiol A Mol Integr Physiol 138 2004 383-390
71. B.R. Whitaker H. Krum Medical management of sea turtles In: M.E. Fowler R.E. Miller (eds.) Zoo and Wild Animal Medicine (ed 4) 1999 W. B. Saunders Philadelphia, PA 217
72. D. Malley Reptiles In: C. Seymour R. Gleed (eds.) Manual of Small Animal Anaesthesia and Analgesia 1999 British Small Animal Veterinary Medical Association Shurdington, United Kingdom 271-281
73. S. Redrobe Anaesthesia and analgesia In: S. Girling P. Raiti (eds.) BSAVA Manual of Reptiles 2004 British Small Animal Veterinary Association Shurdington, United Kingdom 131-146
74. J.E. Cooper Ketamine hydrochloride as an anaesthetic for East African reptiles Vet Rec 95 1974 37-41
75. J.L. Glenn R. Straight C.C. Snyder Clinical use of ketamine hydrochloride as an anesthetic agent for snakes Am J Vet Res 33 1972 1901-1903
76. F.E. Wood K.H. Critchley J.R. Wood Anesthesia in the green sea turtle, Chelonia mydas Am J Vet Res 43 1982 1882-1883
77. W.J. Boever F. Caputo Telazol (CI 744) as an anesthetic agent in reptiles J Zoo An Med 13 1982 59-61
78. V.L. Clyde P.T. Cardeilhac E.R. Jacobson Chemical restraint of american alligators (Alligator mississippiensis) with atracurium or tiletamine-zolazepam J Zoo Wildl Med 25 1994 525-530
79. C.W. Gray M. Bush C.C. Beck Clinical experience using CI-744 in chemical restraint and anesthesia of exotic specimens J Zoo An Med 5 1974 12-21
80. D. Bienzle C.J. Boyd Sedative effects of ketamine and midazolam in snapping turtles (Chelydra serpentina) J Zoo Wildl Med 23 1992 201-204
81. Y.V. Oppenheim P.F. Moon Sedative effects of midazolam in red-eared slider turtles (Trachemys scripta elegans) J Zoo Wildl Med 26 1995 409-413
82. C. Harvey-Clark Midazolam fails to sedate painted turtles (Chrysemys picta) Bull Assoc Reptilian Amphibian Vet 3 1993 7-8
83. P. Holz R.M. Holz Evaluation of ketamine, ketamine/xylazine, and ketamine/midazolam anesthesia in red-eared sliders (Trachemys scripta elegans) J Zoo Wildl Med 25 1994 531-537
84. J.M. Sleeman J. Gaynor Sedative and cardiopulmonary effects of medetomidine and reversal with atipamezole in desert tortoises, (Gopherus agassizii) J Zoo Wildl Med 31 2000 28-35
85. P.M. Dennis D.J. Heard Cardiopulmonary effects of a medetomidine-ketamine combination administered intravenously in gopher tortoises J Am Vet Med Assoc 220 2002 1516-1519
86. B.A. Lock D.J. Heard P. Dennis Preliminary evaluation of medetomidine/ ketamine combinations for immobilization and reversal with atipamezole in three tortoise species Bull Assoc Reptilian Amphibian Vet 8 1998 6-9
87. L.L. Greer K.J. Jenne H.E. Diggs Medetomidine-ketamine anesthesia in red-eared slider turtles, (Trachemys scripta elegans) Contemp Top Lab Anim Sci 40 2001 9-11
88. M.R. Read Evaluation of the use of anesthesia and analgesia in reptiles J Am Vet Med Assoc 224 2004 547-552
89. M. Mauthe von Degerfeld Personal experiences in the use of association tiletamine/zolazepam for anaesthesia of the green iguana, (Iguana iguana) Vet Res Commun 28 suppl 1 2004 351-353
90. C.A. Mosley D. Dyson D.A. Smith Minimum alveolar concentration of isoflurane in green iguanas and the effect of butorphanol on minimum alveolar concentration J Am Vet Med Assoc 222 2003 1559-1564
91. L.L. Brisaben Reactions of the American alligator to several immobilizing drugs Copeia 1966 129-130
92. A.M. Klide L.V. Klein Chemical restraint if three reptilean species J Zoo An Med 4 1973 8-11
93. H. Messel D.R. Stephens Drug immobilization of crocodiles J Wildl Manage 44 1980 295-296
94. R.A. Spiegel T.J. Lane R.E. Larsen et al. Diazepam and succinylcholine chloride for restraint of the American alligator J Am Vet Med Assoc 185 1984 1335-1336
95. G.E. Kaufman R.E. Seymour B.B. Bonner et al. Use of rocuronium for endotracheal intubation of North American Gulf Coast box turtles J Am Vet Med Assoc 222 2003 1111-1115
96. D.A. Belkin Anoxia tolerance: In reptiles Science 139 1963 492-493
97. M.F. Bertelsen C.A. Mosley G.J. Crawshaw et al. Anesthetic potency of sevoflurane and nitrous oxide in mechanically ventilated Dumeril's monitors (Varanus dumerili) J Am Vet Med Assoc 2005 (in press)
98. M.F. Bertelsen C.A. Mosley G.J. Crawshaw et al. Minimum alveolar concentration of isoflurane in mechanically ventilated Dumeril monitors J Am Vet Med Assoc 226 2005 1098-1101
99. A. Maas D. Brunson Comparison of anesthetic potency and cardiopulmonary effects of isoflurane and sevoflurane in colubrid snakes Am Assoc Zoo Vet 2002 306-308
100. C.A. Mosley D. Dyson D.A. Smith The cardiac anesthetic index of isoflurane in green iguanas J Am Vet Med Assoc 222 2003 1565-1568
101. H.W. Calderwood Anesthesia for reptiles J Am Vet Med Assoc 159 1971 1618-1625
102. H.M. Kaplan Anesthesia in amphibians and reptiles Fed Proc 28 1969 1541-1546
103. A.A. Bello A. Bello-Klein A technique to anesthetize turtles with ether Physiol Behav 50 1991 847-848
104. M.J. Murray Cardiology and circulation In: D.R. Mader (ed.) Reptile Medicine and Surgery 1996 W. B. Saunders Toronto, Canada 95-103
105. R.A. Bennett S.J. Divers J. Schumacher et al. Anesthesia Bull Assoc Reptilian Amphibian Vet 9 1999 20-27
106. J. Schumacher Reptiles and amphibians In: J.C. Thurmon W.J. Tranquilli G.J. Benson (eds.) Lumb and Jones' Veterinary Anesthesia (ed 3) 1996 Williams & Wilkins Philadelphia, PA 670-685
107. J.L. Jarchow Hospital care of the reptile patient In: E.R. Jacobson G.V. Kollias (eds.) Exotic Animals 1988 Churchill Livingstone New York, NY 28-30
108. J.J. Kona-Boun A. Silim E. Troncy Immunologic aspects of veterinary anesthesia and analgesia J Am Vet Med Assoc 226 2005 355-363
109. W.W. Muir Pain and stress in: J. Gaynor W.W. Muir (eds.) Handbook of Veterinary Pain Management 2002 Mosby Toronto, Canada 46-59
110. B.D. Lascelles A.E. Waterman P.J. Cripps et al. Central sensitization as a result of surgical pain: Investigation of the pre-emptive value of pethidine for ovariohysterectomy in the rat Pain 62 1995 201-212
111. C.J. Woolf M.S. Chong Preemptive analgesia-treating postoperative pain by preventing the establishment of central sensitization Anesth Analg 77 1993 362-379
112. P.J. Pascoe E.P. Steffey W.D. Black et al. Evaluation of the effect of alfentanil on the minimum alveolar concentration of halothane in horses Am J Vet Res 54 1993 1327-1332
113. E.P. Steffey J.D. Baggot J.H. Eisele et al. Morphine-isoflurane interaction in dogs, swine and rhesus monkeys J Vet Pharmacol Ther 17 1994 202-210
114. E.P. Steffey R. Martucci D. Howland et al. Meperidine-halothane interaction in dogs Can Anaesth Soc J 24 1977 459-467
115. Y.F. Liang S. Terashima Physiological properties and morphological characteristics of cutaneous and mucosal mechanical nociceptive neurons with A-delta peripheral axons in the trigeminal ganglia of crotaline snakes J Comp Neurol 328 1993 88-102
116. M.K. Stoskopf Pain and analgesia in birds, reptiles, amphibians, and fish Invest Ophthalmol Vis Sci 35 1994 775-780
117. C. Gans A.S. Gaunt Muscle architecture and control demands Brain Behav Evol 40 1992 70-81
118. M.D. Mauk R.D. Olson G.J. LaHoste et al. Tonic immobility produces hyperalgesia and antagonizes morphine analgesia Science 213 1981 353-354
119. T.I. Kanui K. Hole Morphine and pethidine antinociception in the crocodile J Vet Pharmacol Ther 15 1992 101-103
120. T.I. Kanui K. Hole J.O. Miaron Nociception in crocodiles: Capsaicin instillation, formalin and hot plate tests Zool Sci 7 1990 537-540
121. H.J. ten Donkelaar R. de Boer-van Huizen A possible pain control system in a non-mammalian vertebrate (a lizard, Gekko gecko) Neurosci Lett 83 1987 65-70
122. J.A. de la Iglesia F.I. Martinez-Guijarro C. Lopez-Garcia Neurons of the medial cortex outer plexiform layer of the lizard, Podarcis hispanica Golgi and immunocytochemical studies J Comp Neurol 341 1994 184-203
123. A. Reiner The distribution of proenkephalin-derived peptides in the central nervous system of turtles J Comp Neurol 259 1987 65-91
124. I. Lindberg L. White Reptilian enkephalins: Implications for the evolution of proenkephalin Arch Biochem Biophys 245 1986 1-7
125. T.B. Ng W.K. Hon C.H. Cheng et al. Evidence for the presence of adrenocorticotropic and opiate-like hormones in the brains of two sea snakes, Hydrophis cyanocinctus and Lapemis hardwickii Gen Comp Endocrinol 63 1986 31-37
126. P.A. Flecknell The relief of pain in laboratory animals Lab Anim 18 1984 147-160
127. D.B. Morton Assessment of pain Vet Rec 119 1986 435
128. A. Polzonetti-Magni F. Facchinetti O. Carnevali et al. Presence and steroidogenetic activity of beta-endorphin in the ovary of the lizard, Podarcis s. sicula raf Biol Reprod 50 1994 1059-1065
129. I.S. Zagon J.W. Sassani G. Allison et al. Conserved expression of the opioid growth factor, [Met5]enkephalin, and the zeta (zeta) opioid receptor in vertebrate cornea Brain Res 671 1995 105-111
130. H. Hinsch C.P. Gandal The effects of etorphine (M-99), oxymorphone hydrochloride and meperidine hydrochloride in reptiles Copeia 1969 404-405
131. A.E. Waterman A. Livingston A. Amin Analgesic activity and respiratory effects of butorphanol in sheep Res Vet Sci 51 1991 19-23
132. R.A. Bennett Anesthesia in: D.R. Mader (eds.) Reptile Medicine and Surgery 1996 W. B. Saunders Toronto, Canada 241-247
133. R.A. Bennett Reptile anesthesia Sem Avian Exot Pet Med 7 1998 30-40
134. K.L. Machin Fish, amphibian, and reptile analgesia Vet Clin North Am Exot Anim Pract 4 2001 19-33
135. D. Malley Reptile anaesthesia and the practicing veterinarian In Practice 19 1997 351-368
136. P.L. Liu H.S. Feldman R. Giasi et al. Comparative CNS toxicity of lidocaine, etidocaine, bupivacaine, and tetracaine in awake dogs following rapid intravenous administration Anesth Analg 62 1983 375-379
137. C.W. Stevens D.N. MacIver L.C. Newman Testing and comparison of non-opioid analgesics in amphibians Contemp Top Lab Anim Sci 40 2001 23-27
138. L.A. Terril-Robb M. Suckow C.F. Grigdesby Evaluation of the analgesic effects of butorphanol tartarate, xylazine hydrochloride, and flunixin meglumine in leopard frogs (Rana pipiens) Contemp Top Lab Anim Sci 35 1996 54-56